Search Results - "Jeneson, J A"

Altered Energetics of Exercise Explain Risk of Rhabdomyolysis in Very Long-Chain Acyl-CoA Dehydrogenase Deficiency by Diekman, E F, Visser, G, Schmitz, J P J, Nievelstein, R A J, de Sain-van der Velden, M, Wardrop, M, Van der Pol, W L, Houten, S M, van Riel, N A W, Takken, T, Jeneson, J A L

“…Rhabdomyolysis is common in very long-chain acyl-CoA dehydrogenase deficiency (VLCADD) and other metabolic myopathies, but its pathogenic basis is poorly…”
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Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects by SCHRAUWEN-HINDERLING, V. B, KOOI, M. E, HESSELINK, M. K. C, JENESON, J. A. L, BACKES, W. H, VAN ECHTELD, C. J. A, VAN ENGELSHOVEN, J. M. A, MENSINK, M, SCHRAUWEN, P

“…Mitochondrial dysfunction and increased intramyocellular lipid (IMCL) content have both been implicated in the development of insulin resistance and type 2…”
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Unchanged muscle fiber conduction velocity relates to mild acidosis during exhaustive bicycling by Schmitz, J. P. J., van Dijk, J. P., Hilbers, P. A. J., Nicolay, K., Jeneson, J. A. L., Stegeman, D. F.

“…Muscle fiber conduction velocity (MFCV) has often been shown to decrease during standardized fatiguing isometric contractions. However, several studies have…”
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A metabolic control analysis of kinetic controls in ATP free energy metabolism in contracting skeletal muscle by Jeneson, J A, Westerhoff, H V, Kushmerick, M J

“…A system analysis of ATP free energy metabolism in skeletal muscle was made using the principles of metabolic control theory. We developed a network model of…”
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Treadmill but not wheel running improves fatigue resistance of isolated extensor digitorum longus muscle in mice by Jeneson, J. A. L., De Snoo, M. W., Verlinden, N. A. T., Joosten, B. J. L. J., Doornenbal, A., Schot, A., Everts, M. E.

“…Aim:  The present study is the first to compare the physiological impact of either forced treadmill or voluntary wheel running exercise on hindlimb muscle in…”
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Efficiency of oxidative work performance of skeletal muscle in patients with cystic fibrosis by de Meer, K, Jeneson, J A, Gulmans, V A, van der Laag, J, Berger, R

“…BACKGROUND--Exercise intolerance in patients with cystic fibrosis is commonly attributed to reduced pulmonary and nutritional status. The possible role of…”
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Combined in vivo and in silico investigations of activation of glycolysis in contracting skeletal muscle by Schmitz, J P J, Groenendaal, W, Wessels, B, Wiseman, R W, Hilbers, P A J, Nicolay, K, Prompers, J J, Jeneson, J A L, van Riel, N A W

“…The hypothesis was tested that the variation of in vivo glycolytic flux with contraction frequency in skeletal muscle can be qualitatively and quantitatively…”
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Increased mitochondrial content rescues in vivo muscle oxidative capacity in long-term high-fat-diet-fed rats by van den Broek, N.M.A, Ciapaite, J, De Feyter, H.M.M.L, Houten, S.M, Wanders, R.J.A, Jeneson, J.A.L, Nicolay, K, Prompers, J.J

“…Mitochondria are thought to play a crucial role in the etiology of muscle insulin resistance (IR). The aim of this study was to gain more insight into the…”
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Quasi-linear relationship between Gibbs free energy of ATP hydrolysis and power output in human forearm muscle by Jeneson, J A, Westerhoff, H V, Brown, T R, Van Echteld, C J, Berger, R

“…The postulated strictly linear descriptions of the rate dependence of oxidative phosphorylation in skeletal muscle on the free energy of ATP hydrolysis (delta…”
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Robust homeostatic control of quadriceps pH during natural locomotor activity in man by Jeneson, J. A. L., Bruggeman, F. J.

“…ABSTRACT It is generally thought that intracellular pH (pHi) of skeletal muscle falls at least 0.5 units during intense activity, but evidence on natural…”
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In vivo 31P MRS detection of an alkaline inorganic phosphate pool with short T1 in human resting skeletal muscle by Kan, H. E., Klomp, D. W. J., Wong, C. S., Boer, V. O., Webb, A. G., Luijten, P. R., Jeneson, J. A.

“…Non‐invasive determination of mitochondrial content is an important objective in clinical and sports medicine. 31P MRS approaches to obtain information on this…”
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Vitamin‐responsive complex I deficiency in a myopathic patient with increased activity of the terminal respiratory chain and lactic acidosis by Bakker, H. D., Scholte, H. R., Jeneson, J. A. L., Busch, H. F. M., Abeling, N. G. G. M., Gennip, A. H.

“…Summary An 11‐year‐old gril with exercise intolerance, fatiguability from early childhood, had high blood lactate levels. Histochemistry showed increased…”
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Computational modelling identifies the impact of subtle anatomical variations between amphibian and mammalian skeletal muscle on spatiotemporal calcium dynamics by Groenendaal, W, Jeneson, J A L, Verhoog, P J, van Riel, N A W, Ten Eikelder, H M M, Nicolay, K, Hilbers, P A J

“…The physical sites of calcium entry and exit in the skeletal muscle cell are distinct and highly organised in space. It was investigated whether the highly…”
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31P-MRS and simultaneous quantification of dynamic human quadriceps exercise in a whole body MR scanner by Rodenburg, J B, de Boer, R W, Jeneson, J A, van Echteld, C J, Bär, P R

“…An ergometer for dynamic quadriceps exercise in a magnetic resonance (MR) scanner is physiologically validated, and its technical aspects are presented. The…”
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Experimental design of 31P MRS assessment of human forearm muscle function: restrictions imposed by functional anatomy by Jeneson, J A, van Dobbenburgh, J O, van Echteld, C J, Lekkerkerk, C, Janssen, W J, Dorland, L, Berger, R, Brown, T R

“…The restrictions imposed by the functional anatomy of the finger flexor muscles on the experimental design of 31P MRS assessment of human forearm muscle…”
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The impact of exogenous ketone body suppletion on energy and pH balance in skeletal muscle during exercise in chronic heart failure patients: a prospective randomized double-blind cross-over study by Voorrips, S N, Jeneson, J A L, Renken, R J, Vijver, M A T, Sibeijn-Kuiper, A J, Zijlstra, S N, Van Veldhuisen, D J, Van Der Meer, P, Westenbrink, B D

“…Abstract Background Heart Failure (HF) is characterized by impediments in exercise capacity. Disruptions in the energy metabolism of skeletal muscle contribute…”
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Two-dimensional 31P-chemical shift imaging of intramuscular heterogeneity in exercising human forearm muscle by Jeneson, J A, Nelson, S J, Vigneron, D B, Taylor, J S, Murphy-Boesch, J, Brown, T R

“…Two-dimensional phosphorus chemical shift imaging (2D-31P-CSI) was used to investigate macroscopic heterogeneity within the flexor digitorum profundus (FDP)…”
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Resting oxygen consumption and in vivo ADP are increased in myopathy due to complex I deficiency by ROEF, M. J, REIJNGOUD, D.-J, JENESON, J. A. L, BERGER, R, DE MEER, K

“…Patients with isolated complex I deficiency (CID) in skeletal muscle mitochondria often present with exercise intolerance as their major clinical symptom. To…”
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1H MR imaging of anatomical compartments within the finger flexor muscles of the human forearm by Jeneson, J A, Taylor, J S, Vigneron, D B, Willard, T S, Carvajal, L, Nelson, S J, Murphy-Boesch, J, Brown, T R

“…Fast T2-weighted 1H MRI following exercise allows investigation of the location of muscle fiber activity within skeletal muscle. Using this method, we have…”
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Body fat distribution in pubertal girls quantified by magnetic resonance imaging by de Ridder, C M, de Boer, R W, Seidell, J C, Nieuwenhoff, C M, Jeneson, J A, Bakker, C J, Zonderland, M L, Erich, W B

“…We examined body fat distribution in relation to anthropometrically derived variables in 24 girls in early and late stages of puberty. The amounts of…”
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