Search Results - "Jendrusch, Michael"
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1
Spatially resolved electrical impedance methods for cell and particle characterization
Published in Electrophoresis (01-01-2020)“…Electrical impedance is an established technique used for cell and particle characterization. The temporal and spectral resolution of electrical impedance have…”
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The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution
Published in Nature communications (21-09-2020)“…The immune system can recognize and attack cancer cells, especially those with a high load of mutation-induced neoantigens. Such neoantigens are abundant in…”
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Impact and characterization of serial structural variations across humans and great apes
Published in Nature communications (13-09-2024)“…Modern sequencing technology enables the systematic detection of complex structural variation (SV) across genomes. However, extensive DNA rearrangements…”
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4
Self-Learning Microfluidic Platform for Single-Cell Imaging and Classification in Flow
Published in Micromachines (Basel) (09-05-2019)“…Single-cell analysis commonly requires the confinement of cell suspensions in an analysis chamber or the precise positioning of single cells in small channels…”
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Deep learning detects genetic alterations in cancer histology generated by adversarial networks
Published in The Journal of pathology (01-05-2021)“…Deep learning can detect microsatellite instability (MSI) from routine histology images in colorectal cancer (CRC). However, ethical and legal barriers impede…”
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A simple approach for detecting HLA‐A 02 alleles in archival formalin‐fixed paraffin‐embedded tissue samples and an application example for studying cancer immunoediting
Published in HLA : immune response genetics (01-01-2023)“…The HLA system represents a central component of the antigen presentation machinery. As every patient possesses a defined set of HLA molecules, only certain…”
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THER-01. Precision brain tumor therapy by AAV-mediated oncogene editing
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Abstract Pediatric high-grade glioma is a heterogeneous group of highly malignant tumors of the central nervous system, with a median overall survival of less…”
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Using histopathology latent diffusion models as privacy-preserving dataset augmenters improves downstream classification performance
Published in Computers in biology and medicine (01-06-2024)“…Latent diffusion models (LDMs) have emerged as a state-of-the-art image generation method, outperforming previous Generative Adversarial Networks (GANs) in…”
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A simple approach for detecting HLA‐A02 alleles in archival formalin‐fixed paraffin‐embedded tissue samples and an application example for studying cancer immunoediting
Published in HLA (01-01-2023)“…The HLA system represents a central component of the antigen presentation machinery. As every patient possesses a defined set of HLA molecules, only certain…”
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Abstract 571: The shared mutation and neo antigen landscape of MMR-deficient colorectal cancers suggests immunoediting during tumor evolution
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract The immune system can recognize and attack cancer cells and their precursors, especially those with a high load of mutation-induced neoantigens. Such…”
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Leveraging implicit knowledge in neural networks for functional dissection and engineering of proteins
Published in Nature machine intelligence (01-05-2019)“…Proteins are nature’s most versatile molecular machines. Deep neural networks trained on large protein datasets have recently been used to tackle the unmet…”
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Publisher Correction: Leveraging implicit knowledge in neural networks for functional dissection and engineering of proteins
Published in Nature machine intelligence (01-06-2019)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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