Ewing's sarcoma with metachronous pulmonary metastasis after successful treatment of osteosarcoma in a child

A rare case of duplicate tumor, osteosarcoma and Ewing's sarcoma, complicated by metachronous pulmonary metastasis in a child is reported. A nine-year-old girl's osteosarcoma was treated by neoadjuvant chemotherapy followed by surgery and adjuvant chemotherapy. Four years later, resection...

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Bibliographic Details
Published in:	Tumori Vol. 95; no. 6; pp. 815 - 818
Main Authors:	Stebnicky, Milan, Belak, Jozef, Bohus, Peter, Gmitter, Frantisek, Jenco, Igor, Tkacova, Ruzena
Format:	Journal Article
Language:	English
Published:	United States 01-11-2009
Subjects:	Adolescent Amputation Antineoplastic Combined Chemotherapy Protocols - therapeutic use Chemotherapy, Adjuvant Child Female Femoral Neoplasms - drug therapy Femoral Neoplasms - pathology Femoral Neoplasms - surgery Femoral Neoplasms - therapy Humans Lung Neoplasms - drug therapy Lung Neoplasms - pathology Lung Neoplasms - surgery Neoadjuvant Therapy - methods Neoplasms, Second Primary - drug therapy Neoplasms, Second Primary - pathology Neoplasms, Second Primary - surgery Osteosarcoma - drug therapy Osteosarcoma - pathology Osteosarcoma - surgery Osteosarcoma - therapy Radiotherapy, Adjuvant Sarcoma, Ewing - drug therapy Sarcoma, Ewing - pathology Sarcoma, Ewing - surgery Thoracic Wall Thoracotomy Treatment Outcome
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Summary:	A rare case of duplicate tumor, osteosarcoma and Ewing's sarcoma, complicated by metachronous pulmonary metastasis in a child is reported. A nine-year-old girl's osteosarcoma was treated by neoadjuvant chemotherapy followed by surgery and adjuvant chemotherapy. Four years later, resection of the chest wall to remove an Ewing's sarcoma had to be performed, followed by chemotherapy and radiotherapy. At the age of 17, the girl underwent a metastasectomy of Ewing's sarcoma metastasis to the lung. Five years later, the patient is free from any recognizable malignant disease. We conclude that after the complete surgical removal of two primary tumors, metastasectomy is an optimal treatment procedure in case of a solitary pulmonary metastasis.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0300-8916 2038-2529
DOI:	10.1177/030089160909500628