Search Results - "Jenal, Mathias"

The Poly(A)-Binding Protein Nuclear 1 Suppresses Alternative Cleavage and Polyadenylation Sites by Jenal, Mathias, Elkon, Ran, Loayza-Puch, Fabricio, van Haaften, Gijs, Kühn, Uwe, Menzies, Fiona M., Vrielink, Joachim A.F. Oude, Bos, Arnold J., Drost, Jarno, Rooijers, Koos, Rubinsztein, David C., Agami, Reuven

“…Alternative cleavage and polyadenylation (APA) is emerging as an important layer of gene regulation. Factors controlling APA are largely unknown. We developed…”
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Scavenger Chemokine (CXC Motif) Receptor 7 (CXCR7) Is a Direct Target Gene of HIC1 (Hypermethylated in Cancer 1) by Van Rechem, Capucine, Rood, Brian R., Touka, Majid, Pinte, Sébastien, Jenal, Mathias, Guérardel, Cateline, Ramsey, Keri, Monté, Didier, Bégue, Agnès, Tschan, Mario P., Stephan, Dietrich A., Leprince, Dominique

“…The tumor suppressor gene HIC1 (Hypermethylated in Cancer 1) that is epigenetically silenced in many human tumors and is essential for mammalian development…”
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The Tumor Suppressor Gene Hypermethylated in Cancer 1 Is Transcriptionally Regulated by E2F1 by Jenal, Mathias, Trinh, Emmanuelle, Britschgi, Christian, Britschgi, Adrian, Roh, Vincent, Vorburger, Stephan A, Tobler, Andreas, Leprince, Dominique, Fey, Martin F, Helin, Kristian, Tschan, Mario P

“…The Hypermethylated in Cancer 1 ( HIC1 ) gene encodes a zinc finger transcriptional repressor that cooperates with p53 to suppress cancer development. We and…”
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The Clinical Effectiveness of Denosumab (Prolia®) for the Treatment of Osteoporosis in Postmenopausal Women, Compared to Bisphosphonates, Selective Estrogen Receptor Modulators (SERM), and Placebo: A Systematic Review and Network Meta-Analysis by Moshi, Magdalena Ruth, Nicolopoulos, Konstance, Stringer, Danielle, Ma, Ning, Jenal, Mathias, Vreugdenburg, Thomas

“…To assess the effectiveness and safety of denosumab (Prolia®) compared to bisphosphonates (alendronate, ibandronate, risedronate, zoledronate), selective…”
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Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening by McDonald, E. Robert, de Weck, Antoine, Schlabach, Michael R., Billy, Eric, Mavrakis, Konstantinos J., Hoffman, Gregory R., Belur, Dhiren, Castelletti, Deborah, Frias, Elizabeth, Gampa, Kalyani, Golji, Javad, Kao, Iris, Li, Li, Megel, Philippe, Perkins, Thomas A., Ramadan, Nadire, Ruddy, David A., Silver, Serena J., Sovath, Sosathya, Stump, Mark, Weber, Odile, Widmer, Roland, Yu, Jianjun, Yu, Kristine, Yue, Yingzi, Abramowski, Dorothee, Ackley, Elizabeth, Barrett, Rosemary, Berger, Joel, Bernard, Julie L., Billig, Rebecca, Brachmann, Saskia M., Buxton, Frank, Caothien, Roger, Caushi, Justina X., Chung, Franklin S., Cortés-Cros, Marta, deBeaumont, Rosalie S., Delaunay, Clara, Desplat, Aurore, Duong, William, Dwoske, Donald A., Eldridge, Richard S., Farsidjani, Ali, Feng, Fei, Feng, JiaJia, Flemming, Daisy, Forrester, William, Galli, Giorgio G., Gao, Zhenhai, Gauter, François, Gibaja, Veronica, Haas, Kristy, Hattenberger, Marc, Hood, Tami, Hurov, Kristen E., Jagani, Zainab, Jenal, Mathias, Johnson, Jennifer A., Jones, Michael D., Kapoor, Avnish, Korn, Joshua, Liu, Jilin, Liu, Qiumei, Liu, Shumei, Liu, Yue, Loo, Alice T., Macchi, Kaitlin J., Martin, Typhaine, McAllister, Gregory, Meyer, Amandine, Mollé, Sandra, Pagliarini, Raymond A., Phadke, Tanushree, Repko, Brian, Schouwey, Tanja, Shanahan, Frances, Shen, Qiong, Stamm, Christelle, Stephan, Christine, Stucke, Volker M., Tiedt, Ralph, Varadarajan, Malini, Venkatesan, Kavitha, Vitari, Alberto C., Wallroth, Marco, Weiler, Jan, Zhang, Jing, Mickanin, Craig, Myer, Vic E., Porter, Jeffery A., Lai, Albert, Bitter, Hans, Lees, Emma, Keen, Nicholas, Kauffmann, Audrey, Stegmeier, Frank, Hofmann, Francesco, Schmelzle, Tobias, Sellers, William R.

“…Elucidation of the mutational landscape of human cancer has progressed rapidly and been accompanied by the development of therapeutics targeting mutant…”
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The clinical effectiveness of denosumab (Prolia®) in patients with hormone-sensitive cancer receiving endocrine therapy, compared to bisphosphonates, selective estrogen receptor modulators (SERM), and placebo: a systematic review and network meta-analysis by Nicolopoulos, Konstance, Moshi, Magdalena Ruth, Stringer, Danielle, Ma, Ning, Jenal, Mathias, Vreugdenburg, Thomas

“…Summary This systematic review (SR) assessed the use of denosumab (Prolia®) to treat osteoporosis in cancer patients receiving endocrine therapy. Denosumab was…”
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E2F mediates enhanced alternative polyadenylation in proliferation by Elkon, Ran, Drost, Jarno, van Haaften, Gijs, Jenal, Mathias, Schrier, Mariette, Vrielink, Joachim A Oude, Agami, Reuven

“…BACKGROUND: The majority of mammalian genes contain multiple poly(A) sites in their 3' UTRs. Alternative cleavage and polyadenylation are emerging as an…”
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CLEC5A (MDL-1) is a novel PU.1 transcriptional target during myeloid differentiation by Batliner, Jasmin, Mancarelli, Maria Michela, Jenal, Mathias, Reddy, Venkateshwar A., Fey, Martin F., Torbett, Bruce E., Tschan, Mario P.

“…C-type lectin domain family 5, member A (CLEC5A), also known as myeloid DNAX activation protein 12 (DAP12)-associating lectin-1 (MDL-1), is a cell surface…”
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Transcriptional regulation of MIR29B by PU.1 (SPI1) and MYC during neutrophil differentiation of acute promyelocytic leukaemia cells by Batliner, Jasmin, Buehrer, Emanuel, Federzoni, Elena A., Jenal, Mathias, Tobler, Andreas, Torbett, Bruce E., Fey, Martin F., Tschan, Mario P.

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Mir-29c and Mir-424 Are Novel Myeloid Differentiation-Associated MicroRNAs in Acute Promyelocytic Leukemia by Batliner, Jasmin, Jenal, Mathias, Fey, Martin F., Tschan, Mario P.

“…MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression at the post-transcriptional level. Recent studies showed that they are…”
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HIC1 tumour suppressor gene is suppressed in acute myeloid leukaemia and induced during granulocytic differentiation by Britschgi, Christian, Jenal, Mathias, Rizzi, Mattia, Mueller, Beatrice U., Torbett, Bruce E., Andres, Anne‐Catherine, Tobler, Andreas, Fey, Martin F., Tschan, Mario P.

“…Summary A hallmark of acute myeloid leukaemia (AML) is a block in differentiation caused by deregulated gene expression. The tumour suppressor Hypermethylated…”
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The Anti-Apoptotic Gene BCL2A1 Is Transcriptionally Regulated by PU.1 by Jenal, Mathias, Reddy, Venkateshwar A., Laedrach, Judith, Shan, Deborah, Tobler, Andreas, Torbett, Bruce E., Fey, Martin F., Tschan, Mario P.

“…PU.1 is a hematopoietic transcriptional regulator that is necessary for the development of both myeloid and B cells. To identify new PU.1 target genes in…”
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Inactivation of the hypermethylated in cancer 1 tumour suppressor--not just a question of promoter hypermethylation? by Jenal, Mathias, Britschgi, Christian, Fey, Martin F, Tschan, Mario P

“…The chromosomal region 17p13.3 is frequently deleted or epigenetically silenced in a variety of human cancers. It includes the hypermethylated in cancer 1…”
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