Search Results - "Jen, S."

Multiple activities of Arl1 GTPase in the trans-Golgi network by Yu, Chia-Jung, Lee, Fang-Jen S

“…ADP-ribosylation factors (Arfs) and ADP-ribosylation factor-like proteins (Arls) are highly conserved small GTPases that function as main regulators of…”
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ARF GTPases and their GEFs and GAPs: concepts and challenges by Sztul, Elizabeth, Chen, Pei-Wen, Casanova, James E, Cherfils, Jacqueline, Dacks, Joel B, Lambright, David G, Lee, Fang-Jen S, Randazzo, Paul A, Santy, Lorraine C, Schürmann, Annette, Wilhelmi, Ilka, Yohe, Marielle E, Kahn, Richard A

“…Detailed structural, biochemical, cell biological, and genetic studies of any gene/protein are required to develop models of its actions in cells. Studying a…”
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Phosphorylation of Arl4A/D promotes their binding by the HYPK chaperone for their stable recruitment to the plasma membrane by Lin, Ming-Chieh, Yu, Chia-Jung, Lee, Fang-Jen S.

“…The Arl4 small GTPases participate in a variety of cellular events, including cytoskeleton remodeling, vesicle trafficking, cell migration, and neuronal…”
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Endosomal Arl4A attenuates EGFR degradation by binding to the ESCRT-II component VPS36 by Lin, Shin-Jin, Lin, Ming-Chieh, Liu, Tsai-Jung, Tsai, Yueh-Tso, Tsai, Ming-Ting, Lee, Fang-Jen S.

“…Ligand-induced epidermal growth factor receptor (EGFR) endocytosis followed by endosomal EGFR signaling and lysosomal degradation plays important roles in…”
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ADP-ribosylation factor-like 4C binding to filamin-A modulates filopodium formation and cell migration by Chiang, Tsai-Shin, Wu, Hsu-Feng, Lee, Fang-Jen S

“…Changes in cell morphology and the physical forces that occur during migration are generated by a dynamic filamentous actin cytoskeleton. The ADP-ribosylation…”
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AMPK promotes Arf6 activation in a kinase-independent manner upon glucose starvation by Chen, Kuan-Jung, Hsu, Jia-Wei, Lee, Fang-Jen S.

“…AMP-activated protein kinase (AMPK) is a crucial cellular nutrient and energy sensor that maintains energy homeostasis. AMPK also governs cancer cell invasion…”
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Plastic contamination of a Galapagos Island (Ecuador) and the relative risks to native marine species by Jones, Jen S., Porter, Adam, Muñoz-Pérez, Juan Pablo, Alarcón-Ruales, Daniela, Galloway, Tamara S., Godley, Brendan J., Santillo, David, Vagg, Jessica, Lewis, Ceri

“…Ecuador's Galapagos Islands and their unique biodiversity are a global conservation priority. We explored the presence, composition and environmental drivers…”
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Sea surface microplastics in the Galapagos: Grab samples reveal high concentrations of particles <200 μm in size by Deakin, Katie, Savage, Georgie, Jones, Jen S., Porter, Adam, Muñoz-Pérez, Juan Pablo, Santillo, David, Lewis, Ceri

“…Plastic pollution in the oceans is increasing, yet most global sea surface data is collected using plankton nets which limits our knowledge of the smaller and…”
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The SNARE-associated protein Sft2 functions in Imh1-mediated SNARE recycling transport upon ER stress by Lai, Chun-Chi, Chiu, Wan-Yun, Chen, Yan-Ting, Wu, Chia-Lu, Lee, Fang-Jen S

“…Vesicular trafficking involving SNARE proteins play a crucial role in the delivery of cargo to the target membrane. Arf-like protein 1 (Arl1) is an important…”
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Arl4D-EB1 interaction promotes centrosomal recruitment of EB1 and microtubule growth by Lin, Shin-Jin, Huang, Chun-Fang, Wu, Tsung-Sheng, Li, Chun-Chun, Lee, Fang-Jen S

“…ADP-ribosylation factor (Arf)-like 4D (Arl4D), one of the Arf-like small GTPases, functions in the regulation of cell morphology, cell migration, and actin…”
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Arl1p regulates spatial membrane organization at the trans-Golgi network through interaction with Arf-GEF Gea2p and flippase Drs2p by Tsai, Pei-Chin, Hsu, Jia-Wei, Liu, Ya-Wen, Chen, Kuan-Yu, Lee, Fang-Jen S

“…ADP ribosylation factors (Arfs) are the central regulators of vesicle trafficking from the Golgi complex. Activated Arfs facilitate vesicle formation through…”
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Cooperative recruitment of Arl4A and Pak1 to the plasma membrane contributes to sustained Pak1 activation for cell migration by Chen, Kuan-Jung, Chiang, Tsai-Chen, Yu, Chia-Jung, Lee, Fang-Jen S

“…Cell migration requires the coordination of multiple signaling pathways involved in membrane dynamics and cytoskeletal rearrangement. The Arf-like small GTPase…”
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Microplastic distribution and composition on two Galápagos island beaches, Ecuador: Verifying the use of citizen science derived data in long-term monitoring by Jones, Jen S., Guézou, Anne, Medor, Sara, Nickson, Caitlin, Savage, Georgie, Alarcón-Ruales, Daniela, Galloway, Tamara S., Muñoz-Pérez, Juan Pablo, Nelms, Sarah E., Porter, Adam, Thiel, Martin, Lewis, Ceri

“…Monitoring beach plastic contamination across space and time is necessary for understanding its sources and ecological effects, and for guiding mitigation…”
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Bottle with a message: The role of story writing as an engagement tool to explore children's perceptions of marine plastic litter by Praet, Estelle, Baeza-Álvarez, Jostein, De Veer, Diamela, Holtmann-Ahumada, Geraldine, Jones, Jen S., Langford, Sarah, Dearte, Jessica Michel, Schofield, John, Thiel, Martin, Wyles, Kayleigh J.

“…As human behaviors play a crucial role in addressing the global threat of plastic pollution, it is vital to understand perceptions about marine plastic litter…”
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Golgin Imh1 and GARP complex cooperate to restore the impaired SNARE recycling transport induced by ER stress by Wang, Yi-Hsun, Chiu, Wan-Yun, Chen, Yan-Ting, Cai, Pei-Juan, Wu, Yu-Chieh, Wu, Jia-Lu, Chen, Bo-Han, Liu, Ya-Wen, Yu, Chia-Jung, Lee, Fang-Jen S.

“…The accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces the unfolded protein response (UPR), which acts through various mechanisms to…”
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ADP-ribosylation factor-like 4A interacts with Robo1 to promote cell migration by regulating Cdc42 activation by Chiang, Tsai-Shin, Lin, Ming-Chieh, Tsai, Meng-Chen, Chen, Chieh-Hsin, Jang, Li-Ting, Lee, Fang-Jen S

“…Cell migration is a highly regulated event that is initiated by cell membrane protrusion and actin reorganization. Robo1, a single-pass transmembrane receptor,…”
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Arl4A and Pak1 cooperative recruitment to plasma membrane contributes to sustained Pak1 activation for cell migration by Chen, Kuan-Jung, Chiang, Tsai-Chen, Yu, Chia-Jung, Lee, Fang-Jen S

“…Cell migration requires the coordination of multiple signaling pathways involved in membrane dynamics and cytoskeletal rearrangement. The Arf-like small GTPase…”
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Action of Arl1 GTPase and golgin Imh1 in Ypt6-independent retrograde transport from endosomes to the trans-Golgi network by Chen, Yan-Ting, Wang, I-Hao, Wang, Yi-Hsun, Chiu, Wan-Yun, Hu, Jen-Hao, Chen, Wen-Hui, Lee, Fang-Jen S

“…The Arf and Rab/Ypt GTPases coordinately regulate membrane traffic and organelle structure by regulating vesicle formation and fusion. Ample evidence has…”
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Snf1/AMP-activated protein kinase activates Arf3p to promote invasive yeast growth via a non-canonical GEF domain by Hsu, Jia-Wei, Chen, Kuan-Jung, Lee, Fang-Jen S.

“…Active GTP-bound Arf GTPases promote eukaryotic cell membrane trafficking and cytoskeletal remodelling. Arf activation is accelerated by guanine…”
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Unfolded protein response regulates yeast small GTPase Arl1p activation at late Golgi via phosphorylation of Arf GEF Syt1p by Hsu, Jia-Wei, Tang, Pei-Hua, Wang, I-Hao, Liu, Chia-Lun, Chen, Wen-Hui, Tsai, Pei-Chin, Chen, Kuan-Yu, Chen, Kuan-Jung, Yu, Chia-Jung, Lee, Fang-Jen S.

“…ADP ribosylation factor (Arf) GTPases are key regulators of membrane traffic at the Golgi complex. In yeast, Arf guanine nucleotide-exchange factor (GEF) Syt1p…”
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