Search Results - "Jen, Emily"

FDA Approval: Blinatumomab for Patients with B-cell Precursor Acute Lymphoblastic Leukemia in Morphologic Remission with Minimal Residual Disease by Jen, Emily Y, Xu, Qing, Schetter, Aaron, Przepiorka, Donna, Shen, Yuan Li, Roscoe, Donna, Sridhara, Rajeshwari, Deisseroth, Albert, Philip, Reena, Farrell, Ann T, Pazdur, Richard

“…On March 29, 2018, the FDA granted accelerated approval for blinatumomab (Blincyto; Amgen, Inc.) for the treatment of adults and children with B-cell precursor…”
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FDA Approval: Gemtuzumab Ozogamicin for the Treatment of Adults with Newly Diagnosed CD33-Positive Acute Myeloid Leukemia by Jen, Emily Y, Ko, Chia-Wen, Lee, Jee Eun, Del Valle, Pedro L, Aydanian, Antonina, Jewell, Charles, Norsworthy, Kelly J, Przepiorka, Donna, Nie, Lei, Liu, Jiang, Sheth, Christopher M, Shapiro, Marjorie, Farrell, Ann T, Pazdur, Richard

“…On September 1, 2017, the FDA granted approval for gemtuzumab ozogamicin (Mylotarg; Pfizer Inc.) in combination with daunorubicin and cytarabine and as a…”
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FDA Approval Summary: Tagraxofusp-erzs For Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm by Jen, Emily Y, Gao, Xin, Li, Liang, Zhuang, Luning, Simpson, Natalie E, Aryal, Baikuntha, Wang, Rong, Przepiorka, Donna, Shen, Yuan Li, Leong, Ruby, Liu, Chao, Sheth, Christopher M, Bowen, Steven, Goldberg, Kirsten B, Farrell, Ann T, Blumenthal, Gideon M, Pazdur, Richard

“…Tagraxofusp-erzs (Elzonris, Stemline) is a cytotoxin that targets CD123-expressing cells. On December 21, 2018, FDA approved tagraxofusp-erzs for the treatment…”
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FDA Approval Summary: Oral Azacitidine for Continued Treatment of Adults with Acute Myeloid Leukemia Unable to Complete Intensive Curative Therapy by Jen, Emily Y, Wang, Xin, Li, Meng, Li, Hongshan, Lee, Shwu-Luan, Ni, Nina, Przepiorka, Donna, Vallejo, Jonathon, Leong, Ruby, Ma, Lian, Gehrke, Brenda J, McLamore, Sherita, Theoret, Marc R, de Claro, R Angelo

“…On September 1, 2020, the FDA granted approval for oral azacitidine (Onureg, CC-486) for continued treatment of adult patients with acute myeloid leukemia…”
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Minimal Residual Disease Data in Hematologic Malignancy Drug Applications and Labeling: An FDA Perspective by Baines, Andrea C, Yazdy, Maryam Sarraf, Kasamon, Yvette L, Ershler, Rachel, Jen, Emily Y, Kanapuru, Bindu, Richardson, Nicholas C, Lane, Ashley, Carioti, Theresa, Theoret, Marc R, Pazdur, Richard, Gormley, Nicole J

“…Minimal residual disease (MRD) is increasingly used as a prognostic biomarker, a measure of clinical efficacy, and a guide for treatment decisions in various…”
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Considerations for Drug Development in Myelodysplastic Syndromes by Sekeres, Mikkael A, Kim, Nina, DeZern, Amy E, Norsworthy, Kelly J, Garcia, Jacqueline S, de Claro, R Angelo, Theoret, Marc R, Jen, Emily Y, Ehrlich, Lori A, Zeidan, Amer M, Komrokji, Rami S

“…Myelodysplastic syndromes (MDS) have historically been challenging diseases for drug development due to their biology, preclinical modeling, and the affected…”
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Sonic Hedgehog Induces Epidermal Growth Factor Dependent Matrix Infiltration in HaCaT Keratinocytes by Bigelow, Rebecca L.H., Jen, Emily Y., Delehedde, Maryse, Chari, Nikhil S., McDonnell, Timothy J.

“…The deregulation of the sonic hedgehog (shh) signaling pathway in epidermal keratinocytes is a primary event leading to the formation of basal cell carcinoma…”
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IL-2 regulates the expression of the tumor suppressor IL-24 in melanoma cells by Jen, Emily Y, Poindexter, Nancy J, Farnsworth, Elizabeth S, Grimm, Elizabeth A

“…Melanoma is notoriously resistant to chemotherapy, but variable responses to biotherapies, including the IFNs and IL-2, provide intriguing avenues for further…”
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Parvovirus infection mimicking a myeloproliferative neoplasm in a toddler with sickle cell disease by Jen, Emily Y., Jackups, Ronald

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The Amplified Voice of Athletes: Measuring the Influence and Efficacy of Sports-Based Activism by Dirks, Emily Jen

“…This research offers an in-depth exploration of athlete activism, through the lens of social identity theory and social cognitive theory as well as advancing…”
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Minimal Residual Disease (MRD) Data in Hematologic Malignancy Drug Applications and Prescribing Information: FDA Analysis by Sarraf Yazdy, Maryam, Baines, Andrea C., Carioti, Theresa, Ershler, Rachel, Jen, Emily Y., Kanapuru, Bindu, Kasamon, Yvette L., Lane, Ashley, Richardson, Nicholas, Theoret, Marc, Gormley, Nicole J.

“…Introduction: In the past decade, multiple studies have reported the prognostic and predictive value of MRD status in specific hematologic malignancies (HM)…”
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Using administrative laboratory result data to describe adverse events by Miller, Tamara P., Getz, Kelly D., Jen, Emily, Huang, Yuan-Shung, Przepiorka, Donna, Li, Yimei, Bagatell, Rochelle, Seif, Alix Eden, Fisher, Brian, Aplenc, Richard

“…Abstract only…”
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IL-24 is expressed during wound repair and inhibits TGFα-induced migration and proliferation of keratinocytes by Poindexter, Nancy J., Williams, Ryan R., Powis, Garth, Jen, Emily, Caudle, Abigail S., Chada, Sunil, Grimm, Elizabeth A.

“…Please cite this paper as: IL‐24 is expressed during wound repair and inhibits TGFα ‐induced migration and proliferation of keratinocytes. Experimental…”
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Interleukin-2 regulates the expression of the tumor suppressor Interleukin-24 in melanoma cells by Jen, Emily Y., Poindexter, Nancy J., Farnsworth, Elizabeth S., Grimm, Elizabeth A.

“…Melanoma is notoriously resistant to chemotherapy, but variable responses to biotherapies, including the IFNs and IL-2, provide intriguing avenues for further…”
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IL-24 is expressed during wound repair and inhibits TGFalpha-induced migration and proliferation of keratinocytes by Poindexter, Nancy J, Williams, Ryan R, Powis, Garth, Jen, Emily, Caudle, Abigail S, Chada, Sunil, Grimm, Elizabeth A

“…Interleukin (IL)-24 is the protein product of melanoma differentiation-associated gene 7 (MDA-7). Originally identified as a tumor suppressor molecule, MDA-7…”
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Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice by Beier, Eric E, Sheu, Tzong-Jen, Resseguie, Emily A, Takahata, Masahiko, Awad, Hani A, Cory-Slechta, Deborah A, Puzas, J Edward

“…Stress during prenatal development is correlated with detrimental cognitive and behavioral outcomes in offspring. However, the long-term impact of prenatal…”
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Anger and depression among incarcerated juvenile delinquents: A pilot intervention by Tellier, Jen Emily

“…This study of incarcerated juvenile delinquents used a pre- and post-test approach for evaluating the efficacy of a 12-week cognitive-behavioral program in the…”
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ColdFusion MX Developer's Handbook by Raymond Camden, Arman Danesh, Hal Helms, Guy Rish, Emily Kim, Shlomy Gantz, Jen deHaan, Peter deHaan, Charles Mohnike, Selene Bainum, John Colasante, William Baum, Kenneth N. Fricklas, Matt Liotta

“…ColdFusion is an extremely powerful web-development tool. Despite its short initial learning curve, attributed to its accessible HTML-like, tag-based syntax,…”
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