Search Results - "Jeffry, Joseph"
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Pain Inhibits GRPR Neurons via GABAergic Signaling in the Spinal Cord
Published in Scientific reports (01-11-2019)“…It has been known that algogens and cooling could inhibit itch sensation; however, the underlying molecular and neural mechanisms remain poorly understood…”
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2
Selective targeting of TRPV1 expressing sensory nerve terminals in the spinal cord for long lasting analgesia
Published in PloS one (15-09-2009)“…Chronic pain is a major clinical problem and opiates are often the only treatment, but they cause significant problems ranging from sedation to deadly…”
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3
Distinct roles of NMB and GRP in itch transmission
Published in Scientific reports (13-11-2017)“…A key question in our understanding of itch coding mechanisms is whether itch is relayed by dedicated molecular and neuronal pathways. Previous studies…”
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4
Unidirectional Cross-Activation of GRPR by MOR1D Uncouples Itch and Analgesia Induced by Opioids
Published in Cell (14-10-2011)“…Spinal opioid-induced itch, a prevalent side effect of pain management, has been proposed to result from pain inhibition. We now report that the μ-opioid…”
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5
Descending Control of Itch Transmission by the Serotonergic System via 5-HT1A-Facilitated GRP-GRPR Signaling
Published in Neuron (Cambridge, Mass.) (19-11-2014)“…Central serotonin (5-hydroxytryptophan, 5-HT) modulates somatosensory transduction, but how it achieves sensory modality-specific modulation remains unclear…”
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6
Chronic itch development in sensory neurons requires BRAF signaling pathways
Published in The Journal of clinical investigation (01-11-2013)“…Chronic itch, or pruritus, is associated with a wide range of skin abnormalities. The mechanisms responsible for chronic itch induction and persistence remain…”
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7
Activation characteristics of transient receptor potential ankyrin 1 and its role in nociception
Published in American Journal of Physiology: Cell Physiology (01-09-2011)“…Transient receptor potential (TRP) ankyrin 1 (TRPA1) is a Ca(2+)-permeant, nonselective cationic channel. It is predominantly expressed in the C afferent…”
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8
Sumatriptan Inhibits TRPV1 Channels in Trigeminal Neurons
Published in Headache (01-05-2012)“…(Headache 2012;52:773‐784) Objective.— To understand a possible role for transient potential receptor vanilloid 1 (TRPV1) ion channels in sumatriptan relief of…”
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Strained agricultural farming under the stress of youths’ career selection tendencies: a case study from Hokkaido (Japan)
Published in Humanities & social sciences communications (20-01-2021)“…Abstract Although job availability in Japan is at its highest in 24 years, the unemployment rate has remained unchanged. On one hand, certain fields are…”
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10
Non-canonical Opioid Signaling Inhibits Itch Transmission in the Spinal Cord of Mice
Published in Cell reports (Cambridge) (17-04-2018)“…Chronic itch or pruritus is a debilitating disorder that is refractory to conventional anti-histamine treatment. Kappa opioid receptor (KOR) agonists have been…”
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Protective effect of iridoid glycosides from Paederia scandens (LOUR.) MERRILL (Rubiaceae) on uric acid nephropathy rats induced by yeast and potassium oxonate
Published in Food and chemical toxicology (01-02-2014)“…[Display omitted] •IGPS is isolated from traditional Chinese herb P. scandens (LOUR.) MERRILL.•Protective effects of IGPS on UAN rats induced by yeast and PO…”
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The right information for the right career selection: can it assist Japan to achieve agricultural sustainability?
Published in Environment, development and sustainability (09-01-2024)Get full text
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Timely explantation of tobramycin-impregnated beads and bone cement to avoid haemodialysis in a patient with worsening renal failure
Published in BMJ case reports (07-02-2022)“…A male patient with right total knee arthroplasty complicated by prosthetic joint infection on intravenous antimicrobials developed an acute kidney injury…”
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14
Itch signaling in the nervous system
Published in Physiology (Bethesda, Md.) (01-08-2011)“…Itch is a major somatic sensation, along with pain, temperature, and touch, detected and relayed by the somatosensory system. Itch can be an acute sensation,…”
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Synergistic activation of Src, ERK and STAT pathways in PBMCs for Staphylococcal enterotoxin A induced production of cytokines and chemokines
Published in Asian Pacific journal of allergy and immunology (01-03-2020)“…Staphylococcal enterotoxin A (SEA) is a well-known superantigen and stimulates human peripheral blood mononuclear cells (PBMCs) involving in the pathogenesis…”
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Modulation of synaptic transmission by TRP channels
Published 01-01-2010“…The first sensory synapse is the site where sensory afferent fibers make synaptic connections with second order neurons. Somatic and craniofacial afferents…”
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Dissertation -
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lewallen, ann‐elise. The fabric of Indigeneity: Ainu identity, gender, and settler colonialism in Japan. xvii, 289 pp., plates, bibliogr. Santa Fe, N.M.: SAR Press, 2016. £45.95 (paper)
Published in Journal of the Royal Anthropological Institute (01-09-2018)Get full text
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Design and fabrication of the polysilicon resonating beam force transducer
Published 01-01-1991“…Doubly clamped beams display a shift in resonant frequency with applied load. Miniaturization and batch fabrication on silicon substrates has been accomplished…”
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Dissertation -
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TRADITIONAL INDIAN 'PNEUMATOLOGY' AS EXPOUNDED BY A. K. COOMARASWAMY
Published 01-01-1985Get full text
Dissertation -
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Is Rx couponing a viable direct-marketing technique?
Published in American pharmacy (01-01-1992)Get more information
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