Search Results - "Jefferies, Johanna M C"

Declining serotype coverage of new pneumococcal conjugate vaccines relating to the carriage of Streptococcus pneumoniae in young children by Tocheva, Anna S, Jefferies, Johanna M.C, Rubery, Henry, Bennett, Jessica, Afimeke, Geraldine, Garland, Joanna, Christodoulides, Myron, Faust, Saul N, Clarke, Stuart C

“…Abstract Background Asymptomatic carriage of the opportunistic pathogen Streptococcus pneumoniae is known to precede the development of invasive disease. Young…”
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Identification of Invasive Serotype 1 Pneumococcal Isolates That Express Nonhemolytic Pneumolysin by Kirkham, Lea-Ann S, Jefferies, Johanna M. C, Kerr, Alison R, Jing, Yu, Clarke, Stuart C, Smith, Andrew, Mitchell, Tim J

“…Recently, there has been an increase in invasive pneumococcal disease (IPD) caused by serotype 1 Streptococcus pneumoniae throughout Europe. Serotype 1 IPD is…”
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Distribution of carried pneumococcal clones in UK children following the introduction of the 7-valent pneumococcal conjugate vaccine: A 3-year cross-sectional population based analysis by Tocheva, Anna S, Jefferies, Johanna M.C, Christodoulides, M, Faust, Saul N, Clarke, Stuart C

“…Highlights • PCV-7 related pneumococcal clones decreased in paediatric carriage after vaccine implementation. • PCV-7 implementation coincided with the…”
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Genetic Analysis of Diverse Disease-Causing Pneumococci Indicates High Levels of Diversity within Serotypes and Capsule Switching by JEFFERIES, Johanna M. C, SMITH, Andrew, CLARKE, Stuart C, DOWSON, Chris, MITCHELL, Timothy J

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types by INVERARITY, Donald, LAMB, Karen, EDWARDS, Giles F. S, DIGGLE, Mathew, ROBERTSON, Chris, GREENHALGH, David, MITCHELL, Tim J, SMITH, Andrew, JEFFERIES, Johanna M. C, CLARKE, Stuart C, MCMENAMIN, Jim

“…We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus…”
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The rise and fall of pneumococcal serotypes carried in the PCV era by Devine, Vanessa T, Cleary, David W, Jefferies, Johanna M.C, Anderson, Rebecca, Morris, Denise E, Tuck, Andrew C, Gladstone, Rebecca A, O'Doherty, Grace, Kuruparan, Priyasharmila, Bentley, Stephen D, Faust, Saul N, Clarke, Stuart C

“…Abstract Streptococcus pneumoniae is a major cause of meningitis, sepsis and pneumonia worldwide. Vaccination using pneumococcal conjugate vaccines (PCV) has…”
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PclA, a pneumococcal collagen-like protein with selected strain distribution, contributes to adherence and invasion of host cells by Paterson, Gavin K., Nieminen, Leena, Jefferies, Johanna M.C., Mitchell, Tim J.

“…Abstract Analysis of Streptococcus pneumoniae sequenced genomes revealed a region present only in selected strains consisting of two ORFs: a putative cell wall…”
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Current methods for capsular typing of Streptococcus pneumoniae by Jauneikaite, Elita, Tocheva, Anna S., Jefferies, Johanna M.C., Gladstone, Rebecca A., Faust, Saul N., Christodoulides, Myron, Hibberd, Martin L., Clarke, Stuart C.

“…Streptococcus pneumoniae is a major respiratory tract pathogen causing pneumococcal disease mainly in children aged less than five years and in the elderly…”
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Genomic Diversity between Strains of the Same Serotype and Multilocus Sequence Type among Pneumococcal Clinical Isolates by Silva, Nuno A, McCluskey, Jackie, Jefferies, Johanna M.C, Hinds, Jason, Smith, Andrew, Clarke, Stuart C, Mitchell, Tim J, Paterson, Gavin K

“…The important human pathogen Streptococcus pneumoniae is known to be a genetically diverse species. We have used comparative genome hybridization (CGH)…”
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13-valent pneumococcal conjugate vaccine (PCV13) by Jefferies, Johanna MC, Macdonald, Emily, Faust, Saul N, Clarke, Stuart C

“…The thirteen valent pneumococcal conjugate vaccine (PCV13, Prevenar 13Ô) is the broader coverage successor to the highly effective seven valent vaccine (PCV7,…”
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Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine by Loman, Nicholas J, Gladstone, Rebecca A, Constantinidou, Chrystala, Tocheva, Anna S, Jefferies, Johanna M C, Faust, Saul N, O'Connor, Leigh, Chan, Jacqueline, Pallen, Mark J, Clarke, Stuart C

“…Streptococcus pneumoniae causes invasive infections, primarily at the extremes of life. A seven-valent conjugate vaccine (PCV7) is used to protect against…”
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Presence of Nonhemolytic Pneumolysin in Serotypes of Streptococcus pneumoniae Associated with Disease Outbreaks by Jefferies, Johanna M. C., Johnston, Calum H. G., Kirkham, Lea-Ann S., Cowan, Graeme J. M., Ross, Kirsty S., Smith, Andrew, Clarke, Stuart C., Brueggemann, Angela B., George, Robert C., Pichon, Bruno, Pluschke, Gerd, Pflüger, Valentin, Mitchell, Tim J.

“…Pneumolysin is an important virulence factor of the human pathogen Streptococcus pneumoniae. Sequence analysis of the ply gene from 121 clinical isolates of S…”
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Risk of Red Queen dynamics in pneumococcal vaccine strategy by Jefferies, Johanna M.C, Clarke, Stuart C, Webb, Jeremy S, Kraaijeveld, Alex R

“…Pathogens increasingly evade current vaccines, and new strategies to control them are needed. There is mounting evidence that replacement of vaccine serotypes…”
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Vaccine preventable meningitis in Malaysia: epidemiology and management by McNeil, Hannah C, Jefferies, Johanna M C, Clarke, Stuart C

“…Worldwide bacterial meningitis accounts for more than one million cases and 135,000 deaths annually. Profound, lasting neurological complications occur in…”
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Pneumococci causing invasive disease in children prior to the introduction of pneumococcal conjugate vaccine in Scotland by Clarke, Stuart C, Jefferies, Johanna M. C, Smith, Andrew J, McMenamin, Jim, Mitchell, Timothy J, Edwards, Giles F. S

“…1 Scottish Meningococcus and Pneumococcus Reference Laboratory, Stobhill Hospital, Balornock Road, Glasgow G21 3UW, UK 2 Division of Infection and Immunity,…”
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Patients with Chronic Obstructive Pulmonary Disease harbour a variation of Haemophilus species by Osman, Karen L., Jefferies, Johanna M. C., Woelk, Christopher H., Devos, Nathalie, Pascal, Thierry G., Mortier, Marie-Cécile, Devaster, Jeanne-Marie, Wilkinson, Tom M. A, Cleary, David W., Clarke, Stuart C.

“…H. haemolyticus is often misidentified as NTHi due to their close phylogenetic relationship. Differentiating between the two is important for correct…”
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Increase in serotype 6C pneumococcal carriage, United Kingdom by Tocheva, Anna S, Jefferies, Johanna M C, Christodoulides, Myron, Faust, Saul N, Clarke, Stuart C

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Comparative Genomics of Carriage and Disease Isolates of Streptococcus pneumoniae Serotype 22F Reveals Lineage-Specific Divergence and Niche Adaptation by Cleary, David W, Devine, Vanessa T, Jefferies, Johanna M C, Webb, Jeremy S, Bentley, Stephen D, Gladstone, Rebecca A, Faust, Saul N, Clarke, Stuart C

“…Streptococcus pneumoniae is a major cause of meningitis, sepsis, and pneumonia worldwide. Pneumococcal conjugate vaccines have been part of the United…”
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Pneumococcal conjugate vaccine implementation in middle-income countries by Tricarico, Serena, McNeil, Hannah C, Cleary, David W, Head, Michael G, Lim, Victor, Yap, Ivan Kok Seng, Wie, Chong Chun, Tan, Cheng Siang, Norazmi, Mohd Nor, Aziah, Ismail, Cheah, Eddy Seong Guan, Faust, Saul N, Jefferies, Johanna M C, Roderick, Paul J, Moore, Michael, Yuen, Ho Ming, Newell, Marie-Louise, McGrath, Nuala, Doncaster, C Patrick, Kraaijeveld, Alex R, Webb, Jeremy S, Clarke, Stuart C

“…Since 2000, the widespread adoption of pneumococcal conjugate vaccines (PCVs) has had a major impact in the prevention of pneumonia. Limited access to…”
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Carriage of upper respiratory tract pathogens in rural communities of Sarawak, Malaysian Borneo by Morris, Denise E, McNeil, Hannah, Hocknell, Rebecca E, Anderson, Rebecca, Tuck, Andrew C, Tricarico, Serena, Norazmi, Mohd Nor, Lim, Victor, Siang, Tan Cheng, Lim, Patricia Kim Chooi, Wie, Chong Chun, Cleary, David W, Yap, Ivan Kok Seng, Clarke, Stuart C

“…Pneumonia is a leading cause of death in Malaysia. Whilst many studies have reported the aetiology of pneumonia in Western countries, the epidemiology of…”
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