Search Results - "Jeevakumar, Vivek"
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Schizophrenia-Like Dopamine Release Abnormalities in a Mouse Model of NMDA Receptor Hypofunction
Published in Schizophrenia bulletin (01-01-2019)“…Abstract Amphetamine-induced augmentation of striatal dopamine and its blunted release in prefrontal cortex (PFC) is a hallmark of schizophrenia…”
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Neuropsychiatric Phenotypes Produced by GABA Reduction in Mouse Cortex and Hippocampus
Published in Neuropsychopharmacology (New York, N.Y.) (06-12-2017)Get full text
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Spatial and temporal boundaries of NMDA receptor hypofunction leading to schizophrenia
Published in NPJ schizophrenia (03-02-2017)“…The N -methyl- d -aspartate receptor hypofunction is one of the most prevalent models of schizophrenia. For example, healthy subjects treated with…”
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Ketamine Administration During the Second Postnatal Week Alters Synaptic Properties of Fast-Spiking Interneurons in the Medial Prefrontal Cortex of Adult Mice
Published in Cerebral cortex (New York, N.Y. 1991) (01-03-2016)“…The N-methyl-D-aspartic acid (NMDA)-hypofunction theory of schizophrenia suggests that schizophrenia is associated with a loss of NMDA receptors, specifically…”
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Peroxynitrite Contributes to Behavioral Responses, Increased Trigeminal Excitability, and Changes in Mitochondrial Function in a Preclinical Model of Migraine
Published in The Journal of neuroscience (01-03-2023)“…Administration of a nitric oxide (NO) donor triggers migraine attacks, but the mechanisms by which this occurs are unknown. Reactive nitroxidative species,…”
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IL-6 induced upregulation of T-type Ca2+ currents and sensitization of DRG nociceptors is attenuated by MNK inhibition
Published in Journal of neurophysiology (01-07-2020)“…Phosphorylation of the 5′ cap-binding protein eIF4E by MAPK-interacting kinases (MNK1/2) is important for nociceptor sensitization and the development of…”
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Convergence of peptidergic and non‐peptidergic protein markers in the human dorsal root ganglion and spinal dorsal horn
Published in Journal of comparative neurology (1911) (01-07-2021)“…Peripheral sensory neurons are characterized by their size, molecular profiles, and physiological responses to specific stimuli. In mouse, the peptidergic and…”
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Ketamine administration during the second postnatal week induces enduring schizophrenia-like behavioral symptoms and reduces parvalbumin expression in the medial prefrontal cortex of adult mice
Published in Behavioural brain research (01-04-2015)“…•Ketamine administration in mice on PND 7, 9 and 11.•Characterization of schizophrenia-like behavioral phenotype in adulthood.•Loss of parvalbumin…”
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IL-6 induced upregulation of T-type Ca 2+ currents and sensitization of DRG nociceptors is attenuated by MNK inhibition
Published in Journal of neurophysiology (01-07-2020)“…In this study, we show that the MNK inhibitor and anti-tumor agent eFT508 (tomivosertib) is effective in attenuating IL-6 induced sensitization of dorsal root…”
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Neuropsychiatric Phenotypes Produced by GABA Reduction in Mouse Cortex and Hippocampus
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2018)“…Whereas cortical GAD67 reduction and subsequent GABA level decrease are consistently observed in schizophrenia and depression, it remains unclear how these…”
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Antioxidant Treatment in Male Mice Prevents Mitochondrial and Synaptic Changes in an NMDA Receptor Dysfunction Model of Schizophrenia
Published in eNeuro (01-07-2017)“…Glutamate theories of schizophrenia suggest that the disease is associated with a loss of NMDA receptors, specifically on GABAergic parvalbumin-expressing…”
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Electroencephalography theta differences between object nouns and action verbs when identifying semantic relations
Published in Language, cognition and neuroscience (03-07-2015)“…Nouns and verbs differ in their semantic properties and relationships with other words in the lexicon. This study uses electroencephalography (EEG) to…”
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