Search Results - "Jee, Wona"
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The Antitumor Effect of Timosaponin A3 through c-Myc Inhibition in Colorectal Cancer Cells and Combined Treatment Effect with 5-FU or Doxorubicin
Published in International journal of molecular sciences (07-10-2022)“…Timosaponin A3 (TA3), extracted from the rhizome of Anemarrhenaasphodeloides Bunge, has been reported to affect various diseases, such as cancer, Alzheimer’s…”
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2
Antitumor Effect of Cycloastragenol in Colon Cancer Cells via p53 Activation
Published in International journal of molecular sciences (02-12-2022)“…Colorectal cancer cell (CRC) is the fourth most common cancer in the world. There are several chemotherapy drugs available for its treatment, though they have…”
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3
Viscum album Induces Apoptosis by Regulating STAT3 Signaling Pathway in Breast Cancer Cells
Published in International journal of molecular sciences (26-07-2023)“…In this study, we investigated the potential anticancer effects of , a parasitic plant that grows on (VaM) on breast cancer cells, and explored the underlying…”
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4
Anti-Obesity Effect of Polygalin C Isolated from Polygala japonica Houtt. via Suppression of the Adipogenic and Lipogenic Factors in 3T3-L1 Adipocytes
Published in International journal of molecular sciences (01-10-2021)“…Obesity is a risk factor for metabolic diseases including type 2 diabetes, nonalcoholic steatohepatitis (NASH), heart diseases, and cancer. This study aimed to…”
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5
Lycium chinense Mill Induces Anti-Obesity and Anti-Diabetic Effects In Vitro and In Vivo
Published in International journal of molecular sciences (06-08-2024)“…This study investigated the effects of Mill (LCM) extract on obesity and diabetes, using both in vitro and high-fat diet (HFD)-induced obesity mouse models. We…”
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6
Momordicae Semen inhibits migration and induces apoptotic cell death by regulating c-Myc and CNOT2 in human pancreatic cancer cells
Published in Scientific reports (07-08-2023)“…Pancreatic cancer(PC) is less common than other cancers; however, it has a poor prognosis. Therefore, studying novel target signaling and anticancer agents is…”
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Anti-inflammatory Effect of Symplocos prunifolia Extract in an In Vitro Model of Acute Pneumonia
Published in Plant foods for human nutrition (Dordrecht) (01-12-2024)“…Acute pneumonia is a respiratory disease characterized by inflammation within the lung tissue, exhibiting higher morbidity rates and mortality rates among…”
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Ophiopogonin D increase apoptosis by activating p53 via ribosomal protein L5 and L11 and inhibiting the expression of c-Myc via CNOT2
Published in Frontiers in pharmacology (09-12-2022)“…Ophiopogonin D (OP-D), which is extracted from the root tuber of , is well known for its anti-inflammatory, anti-oxidant, and anti-cancer effects. It is also…”
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9
Euonymus sachalinensis Induces Apoptosis by Inhibiting the Expression of c-Myc in Colon Cancer Cells
Published in Molecules (Basel, Switzerland) (14-04-2023)“…We hypothesized that (ES) induces apoptosis by inhibiting the expression of c-Myc in colon cancer cells, and this study proved that the methanol extract of ES…”
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10
Acetylcorynoline Induces Apoptosis and G2/M Phase Arrest through the c-Myc Signaling Pathway in Colon Cancer Cells
Published in International journal of molecular sciences (18-12-2023)“…Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide, and despite advances in treatment, survival rates are still low; therefore, the…”
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11
Isosinensetin Stimulates Glucagon-like Peptide-1 Secretion via Activation of hTAS2R50 and the G βγ -Mediated Signaling Pathway
Published in International journal of molecular sciences (12-02-2023)“…Bitter taste receptors (TAS2Rs) are G protein-coupled receptors localized in the taste buds of the tongue. They may also be present in non-lingual organs,…”
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12
Timosaponin A3 Induces Anti-Obesity and Anti-Diabetic Effects In Vitro and In Vivo
Published in International journal of molecular sciences (01-03-2024)“…Obesity is a serious global health challenge, closely associated with numerous chronic conditions including type 2 diabetes. Bunge (AA) known as Jimo has been…”
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13
Timosaponin A3 Inhibits Palmitate and Stearate through Suppression of SREBP-1 in Pancreatic Cancer
Published in Pharmaceutics (27-04-2022)“…Timosaponin A3 (TA3) was demonstrated as a potent anticancer chemical by several studies. Although the effects of inhibiting growth, metastasis, and…”
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14
Identification of allergens in Acorus gramineus using protein analysis
Published in Molecular & cellular toxicology (2024)“…Background Food allergy reactions have been increasing over the past 5 years. In addition, we are always exposed to the risk of allergies because the herbal…”
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15
Gancaonin N from Glycyrrhiza uralensis Attenuates the Inflammatory Response by Downregulating the NF-κB/MAPK Pathway on an Acute Pneumonia In Vitro Model
Published in Pharmaceutics (06-07-2021)“…Acute pneumonia is an inflammatory disease caused by several pathogens, with symptoms such as fever and chest pain, to which children are particularly…”
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Rosa laevigata Attenuates Allergic Asthma Exacerbated by Water-Soluble PM by Downregulating the MAPK Pathway
Published in Frontiers in pharmacology (28-06-2022)“…Exposure to water-soluble particulate matter (WPM) containing heavy metals can cause severe inflammatory responses and trigger and exacerbate the onset of…”
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17
Anti-inflammatory and relaxation effects of Ulmus pumilla L. on EGF-inflamed bronchial epithelial and asthmatic bronchial smooth muscle cells
Published in Molecular & cellular toxicology (2024)“…Background Ulmus Pumila L. (UPL), the roots of a tree species of elm, has been prescribed for immunity-related diseases, such as dermatitis, mastitis, and…”
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18
Helixor-M Suppresses Immunostimulatory Activity through TLR4-Dependent NF-κB Pathway in RAW 264.7 Cells
Published in Life (Basel, Switzerland) (01-02-2023)“…Inflammation causes a protective immune response, which can be observed by examining the inflammatory responses of macrophages. Macrophages release various…”
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Isosinensetin Stimulates Glucagon-like Peptide-1 Secretion via Activation of hTAS2R50 and the G[sub.βγ]-Mediated Signaling Pathway
Published in International journal of molecular sciences (01-02-2023)“…Bitter taste receptors (TAS2Rs) are G protein-coupled receptors localized in the taste buds of the tongue. They may also be present in non-lingual organs,…”
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20
IEuonymus sachalinensis/I Induces Apoptosis by Inhibiting the Expression of c-Myc in Colon Cancer Cells
Published in Molecules (Basel, Switzerland) (01-04-2023)“…We hypothesized that Euonymus sachalinensis (ES) induces apoptosis by inhibiting the expression of c-Myc in colon cancer cells, and this study proved that the…”
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