Cytotoxic effect of some medicinal plants from Asteraceae family on J-45.01 leukemic cell line--pilot study

In this study the in vitro cytotoxic properties of ethanol extracts from the herbs, inflorescents and roots of selected Asteraceae species: Arctium lappa, Artemisia absinthium, Calendula officinalis, Centaurea cyanus, Tanacetum vulgare and Tragopogon pratensis on J-45.01 human acute T leukemia cell...

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Bibliographic Details
Published in:	Acta Poloniae pharmaceutica Vol. 69; no. 2; pp. 263 - 268
Main Authors:	Wegiera, Magdalena, Smolarz, Helena D, Jedruch, Marcin, Korczak, Magdalena, Koproń, Kamila
Format:	Journal Article
Language:	English
Published:	Poland 01-03-2012
Subjects:	Antineoplastic Agents, Phytogenic - pharmacology Apoptosis - drug effects Asteraceae - chemistry Humans Jurkat Cells Pilot Projects Plant Extracts - pharmacology Plants, Medicinal - chemistry
Online Access:	Get full text
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Summary:	In this study the in vitro cytotoxic properties of ethanol extracts from the herbs, inflorescents and roots of selected Asteraceae species: Arctium lappa, Artemisia absinthium, Calendula officinalis, Centaurea cyanus, Tanacetum vulgare and Tragopogon pratensis on J-45.01 human acute T leukemia cell line was examined. All tested samples possess antileukemic properties and induce cells death via apoptosis. The correlation between antileukemic activity and total polyphenol content was determined.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0001-6837