Search Results - "Jean-louis Sebedio"

Development of a Quantitative Metabolomic Approach to Study Clinical Human Fecal Water Metabolome Based on Trimethylsilylation Derivatization and GC/MS Analysis by Gao, Xianfu, Pujos-Guillot, Estelle, Sébédio, Jean-Louis

“…Metabolomic analysis of human fecal water recently aroused increasing attention with the importance of fecal metabolome in exploring the relationships between…”
Get full text

Formation Kinetics of Monomeric Cyclic Fatty Acid Methyl Esters of Alpha‐Linolenic Acid: Effects of Mono cis/trans Isomers by Desmarais, Amélie, Sébédio, Jean‐Louis, Belkacemi, Khaled, Arul, Joseph, Angers, Paul

“…Cyclic fatty acid monomers (CFAM) are formed at low levels in edible oils during thermal processing operations such as frying or refining, and inevitably…”
Get full text

Colonic Transit Time Is a Driven Force of the Gut Microbiota Composition and Metabolism: In Vitro Evidence by Tottey, William, Feria-Gervasio, David, Gaci, Nadia, Laillet, Brigitte, Pujos, Estelle, Martin, Jean-François, Sebedio, Jean-Louis, Sion, Benoit, Jarrige, Jean-François, Alric, Monique, Brugère, Jean-François

“…Human gut microbiota harbors numerous metabolic properties essential for the host's health. Increased intestinal transit time affects a part of the population…”
Get full text

Metabolic syndrome and dairy product consumption: Where do we stand? by Sébédio, Jean-Louis, Malpuech Brugere, Corinne

“…Shifts in food composition and in dietary pattern as well as a modification in physical activity have led to increasing prevalence of overweight and obesity…”
Get full text

Resistant starch intake partly restores metabolic and inflammatory alterations in the liver of high-fat-diet-fed rats by Polakof, Sergio, Díaz-Rubio, María Elena, Dardevet, Dominique, Martin, Jean-François, Pujos-Guillot, Estelle, Scalbert, Augustin, Sebedio, Jean-Louis, Mazur, Andrzej, Comte, Blandine

“…Insulin resistance (IR) constitutes the most important feature of the metabolic syndrome, whose prevalence is highly associated to the consumption of Western…”
Get full text

Alterations of HDL particle phospholipid composition and role of inflammation in rheumatoid arthritis by Giraud, Charlotte, Tournadre, Anne, Pereira, Bruno, Dutheil, Frédéric, Soubrier, Martin, Lhomme, Marie, Kontush, Anatol, Sébédio, Jean-Louis, Capel, Frédéric

“…The increased cardiovascular risk in RA (rheumatoid arthritis) cannot be explained by common quantitative circulating lipid parameters. The objective of the…”
Get full text

Influence of acute phytochemical intake on human urinary metabolomic profiles by Walsh, Marianne C, Brennan, Lorraine, Pujos-Guillot, Estelle, Sébédio, Jean-Louis, Scalbert, Augustin, Fagan, Ailís, Higgins, Desmond G, Gibney, Michael J

“…BACKGROUND: Diversity in dietary intake contributes to variation in human metabolomic profiles and artifacts from acute dietary intake can affect metabolomics…”
Get full text

Cyclic Fatty Acids Found in Frying Oils are Detoxified via Classical Drug Metabolic Pathway but also by β-Oxidation and Eliminated as Conjugates in Rats by Desmarais, Amélie, Pujos-Guillot, Estelle, Lyan, Bernard, Martin, Jean-François, Leblanc, Nadine, Angers, Paul, Sébédio, Jean-Louis

“…Cyclic fatty acid monomers (CFAM) are mainly formed during heat treatments, such as frying, of edible oils. These fatty acids are mixtures of disubstituted…”
Get full text

Three-stage continuous culture system with a self-generated anaerobia to study the regionalized metabolism of the human gut microbiota by Feria-Gervasio, David, Tottey, William, Gaci, Nadia, Alric, Monique, Cardot, Jean-Michel, Peyret, Pierre, Martin, Jean-François, Pujos, Estelle, Sébédio, Jean-Louis, Brugère, Jean-François

“…The technical and ethical difficulties in studying the gut microbiota in vivo warrant the development and improvement of in vitro systems able to simulate and…”
Get full text

Development and validation of a UPLC/MS method for a nutritional metabolomic study of human plasma by Pereira, Hélène, Martin, Jean-François, Joly, Charlotte, Sébédio, Jean-Louis, Pujos-Guillot, Estelle

“…In order to study the effect of a diet on metabolites found in body fluids such as plasma, we have developed and validated a UPLC/MS method. While methods…”
Get full text

Metabolomics in evaluation of glucose disorders by Sébédio, Jean-Louis, Pujos-Guillot, Estelle, Ferrara, Marc

“…PURPOSE OF REVIEWRecent advances in metabolomic tools now permit to characterize dysregulated metabolic pathways in various diseases associated with the…”
Get full text

Postprandial metabolic events in mini-pigs: new insights from a combined approach using plasma metabolomics, tissue gene expression, and enzyme activity by Polakof, Sergio, Rémond, Didier, Rambeau, Mathieu, Pujos-Guillot, Estelle, Sébédio, Jean-Louis, Dardevet, Dominique, Comte, Blandine, Savary-Auzeloux, Isabelle

“…To unravel metabolic adaptations preceding the occurrence of metabolic dysregulations, a nutritional challenge appears as the best tool capable to reveal…”
Get full text

Metabolomics reveals differential metabolic adjustments of normal and overweight subjects during overfeeding by Morio, Beatrice, Comte, Blandine, Martin, Jean-François, Chanseaume, Emilie, Alligier, Maud, Junot, Christophe, Lyan, Bernard, Boirie, Yves, Vidal, Hubert, Laville, Martine, Pujos-Guillot, Estelle, Sébédio, Jean-Louis

“…Changes in eating habits, food composition and processing are involved in the “nutritional transition” that accompanied the obesity pandemic and the burst of…”
Get full text

Analysis of eicosapentaenoic and docosahexaenoic acid geometrical isomers formed during fish oil deodorization by Fournier, Véronique, Juanéda, Pierre, Destaillats, Frédéric, Dionisi, Fabiola, Lambelet, Pierre, Sébédio, Jean-Louis, Berdeaux, Olivier

“…Addition of long-chain polyunsaturated fatty acids (LC-PUFAs) from marine oil into food products implies preliminary refining procedures of the oil which…”
Get full text

Cis-9, trans- 11 and trans-10, cis-12 conjugated linoleic acid (CLA) do not affect the plasma lipoprotein profile in moderately overweight subjects with LDL phenotype B by Naumann, Elke, Carpentier, Yvon A., Saebo, Asgeir, Lassel, Taous S., Chardigny, Jean-Michel, Sébédio, Jean-Louis, Mensink, Ronald P.

“…Results of a pilot study suggested that cis-9, trans-11 conjugated linoleic acid (CLA) improved LDL phenotype in moderately overweight subjects with LDL…”
Get full text

Rumenic Acid Significantly Reduces Plasma Levels of LDL and Small Dense LDL Cholesterol in Hamsters Fed a Cholesterol- and Lipid-Enriched Semi-Purified Diet by LeDoux, Martial, Laloux, Laurent, Fontaine, Jean-Jacques, Carpentier, Yvon A, Chardigny, Jean-Michel, Sébédio, Jean-Louis

“…Conjugated linoleic acids (CLAs) consist of a series of positional and geometrical isomers of linoleic acid. CLA have been reported to beneficially affect…”
Get full text

Formation of Modified Fatty Acids and Oxyphytosterols during Refining of Low Erucic Acid Rapeseed Oil by Lambelet, Pierre, Grandgirard, André, Gregoire, Stéphane, Juaneda, Pierre, Sebedio, Jean-Louis, Bertoli, Constantin

“…Formation of trans fatty acids and cyclic fatty acid monomers was investigated during refining of low erucic acid rapeseed oil. The first steps of the refining…”
Get full text

Detection of lactobacillic acid in low erucic rapeseed oil—A note of caution when quantifying cyclic fatty acid monomers in vegetable oils by Berdeaux, Olivier, Gregoire, Stéphane, Fournier, Cindie, Christie, William W., Lambelet, Pierre, Sébédio, Jean-Louis

“…The purpose of this work was to identify an unknown component which has been detected during the analysis of cyclic fatty acid monomers (CFAMs) in low erucic…”
Get full text

Metabolite analysis of human fecal water by gas chromatography/mass spectrometry with ethyl chloroformate derivatization by Gao, Xianfu, Pujos-Guillot, Estelle, Martin, Jean-François, Galan, Pilar, Juste, Catherine, Jia, Wei, Sebedio, Jean-Louis

“…Fecal water is a complex mixture of various metabolites with a wide range of physicochemical properties and boiling points. The analytical method developed…”
Get full text

Resveratrol prevents the wasting disorders of mechanical unloading by acting as a physical exercise mimetic in the rat by Momken, Iman, Stevens, Laurence, Bergouignan, Audrey, Desplanches, Dominique, Rudwill, Floriane, Chery, Isabelle, Zahariev, Alexandre, Zahn, Sandrine, Stein, T. Peter, Sebedio, Jean Louis, Pujos‐Guillot, Estelle, Falempin, Maurice, Simon, Chantal, Coxam, Véronique, Andrianjafiniony, Tany, Gauquelin‐Koch, Guillemette, Picquet, Florence, Blanc, Stéphane

“…ABSTRACT Long‐term spaceflight induces hypokinesia and hypodynamia, which, along microgravity per se, result in a number of significant physiological…”
Get full text