Search Results - "Jean-francois Brugere"

The host-associated archaeome by Borrel, Guillaume, Brugère, Jean-François, Gribaldo, Simonetta, Schmitz, Ruth A., Moissl-Eichinger, Christine

“…Host-associated microbial communities have an important role in shaping the health and fitness of plants and animals. Most studies have focused on the…”
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Archaea and the human gut:New beginning of an old story by Nadia Gaci Guillaume Borrel William Tottey Paul William O’Toole Jean-Fran?ois Brugère

“…Methanogenic archaea are known as human gut inhabitants since more than 30 years ago through the detection of methane in the breath and isolation of two…”
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Genomics and metagenomics of trimethylamine-utilizing Archaea in the human gut microbiome by Borrel, Guillaume, McCann, Angela, Deane, Jennifer, Neto, Marta C, Lynch, Denise B, Brugère, Jean- François, O'Toole, Paul W

“…The biological significance of Archaea in the human gut microbiota is largely unclear. We recently reported genomic and biochemical analyses of the…”
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Genome Sequence of “Candidatus Methanomethylophilus alvus” Mx1201, a Methanogenic Archaeon from the Human Gut Belonging to a Seventh Order of Methanogens by Borrel, Guillaume, Harris, Hugh M. B, Tottey, William, Mihajlovski, Agnès, Parisot, Nicolas, Peyretaillade, Eric, Peyret, Pierre, Gribaldo, Simonetta, O'Toole, Paul W, Brugère, Jean-François

“…We report the draft genome sequence of “Candidatus Methanomethylophilus alvus” Mx1201, a methanogen present in the human gut. It was enriched from human feces…”
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A catalogue of 1,167 genomes from the human gut archaeome by Chibani, Cynthia Maria, Mahnert, Alexander, Borrel, Guillaume, Almeida, Alexandre, Werner, Almut, Brugère, Jean-François, Gribaldo, Simonetta, Finn, Robert D., Schmitz, Ruth A., Moissl-Eichinger, Christine

“…The human gut microbiome plays an important role in health, but its archaeal diversity remains largely unexplored. In the present study, we report the analysis…”
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Archaea, specific genetic traits, and development of improved bacterial live biotherapeutic products: another face of next-generation probiotics by Fadhlaoui, Khaled, Arnal, Marie-Edith, Martineau, Matthieu, Camponova, Paméla, Ollivier, Bernard, O’Toole, Paul W., Brugère, Jean-François

“…Trimethylamine (TMA) and its oxide TMAO are important biomolecules involved in disease-associated processes in humans (e.g., trimethylaminuria and…”
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Phylogenomic data support a seventh order of Methylotrophic methanogens and provide insights into the evolution of Methanogenesis by Borrel, Guillaume, O'Toole, Paul W, Harris, Hugh M B, Peyret, Pierre, Brugère, Jean-François, Gribaldo, Simonetta

“…Increasing evidence from sequence data from various environments, including the human gut, suggests the existence of a previously unknown putative seventh…”
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Fecal microbiota variation across the lifespan of the healthy laboratory rat by Flemer, Burkhardt, Gaci, Nadia, Borrel, Guillaume, Sanderson, Ian R., Chaudhary, Prem P., Tottey, William, O'Toole, Paul W., Brugère, Jean-François

“…Laboratory rats are commonly used in life science research as a model for human biology and disease, but the composition and development of their gut…”
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Archaebiotics: Proposed therapeutic use of archaea to prevent trimethylaminuria and cardiovascular disease by Brugère, Jean-François, Borrel, Guillaume, Gaci, Nadia, Tottey, William, O'Toole, Paul W, Malpuech-Brugère, Corinne

“…Trimethylamine (TMA) is produced by gut bacteria from dietary ingredients. In individuals with a hereditary defect in flavin-containing monooxygenase 3,…”
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Colonic Transit Time Is a Driven Force of the Gut Microbiota Composition and Metabolism: In Vitro Evidence by Tottey, William, Feria-Gervasio, David, Gaci, Nadia, Laillet, Brigitte, Pujos, Estelle, Martin, Jean-François, Sebedio, Jean-Louis, Sion, Benoit, Jarrige, Jean-François, Alric, Monique, Brugère, Jean-François

“…Human gut microbiota harbors numerous metabolic properties essential for the host's health. Increased intestinal transit time affects a part of the population…”
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Growth temperature and chromatinization in archaea by Hocher, Antoine, Borrel, Guillaume, Fadhlaoui, Khaled, Brugère, Jean-François, Gribaldo, Simonetta, Warnecke, Tobias

“…DNA in cells is associated with proteins that constrain its structure and affect DNA-templated processes including transcription and replication. HU and…”
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Molecular evaluation of the human gut methanogenic archaeal microbiota reveals an age-associated increase of the diversity by Mihajlovski, Agnès, Doré, Joël, Levenez, Florence, Alric, Monique, Brugère, Jean-François

“…Summary The methanogenic diversity of the human intestinal microbiota has long been viewed as composed of two Methanobacteriales: Methanobrevibacter smithii…”
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A putative new order of methanogenic Archaea inhabiting the human gut, as revealed by molecular analyses of the mcrA gene by Mihajlovski, Agnès, Alric, Monique, Brugère, Jean-François

“…The diversity of methanogenic Archaea from the gut of 6 humans was investigated by targeting mcrA, a molecular metabolic marker of methanogenesis. Three…”
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ASaiM: a Galaxy-based framework to analyze microbiota data by Batut, Bérénice, Gravouil, Kévin, Defois, Clémence, Hiltemann, Saskia, Brugère, Jean-François, Peyretaillade, Eric, Peyret, Pierre

“…New generations of sequencing platforms coupled to numerous bioinformatics tools have led to rapid technological progress in metagenomics and…”
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Whole Rye Consumption Improves Blood and Liver n-3 Fatty Acid Profile and Gut Microbiota Composition in Rats by Ounnas, Fayçal, Privé, Florence, Salen, Patricia, Gaci, Nadia, Tottey, William, Calani, Luca, Bresciani, Letizia, López-Gutiérrez, Noelia, Hazane-Puch, Florence, Laporte, François, Brugère, Jean-François, Del Rio, Daniele, Demeilliers, Christine, de Lorgeril, Michel

“…Whole rye (WR) consumption seems to be associated with beneficial health effects. Although rye fiber and polyphenols are thought to be bioactive, the…”
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Unique Characteristics of the Pyrrolysine System in the 7th Order of Methanogens: Implications for the Evolution of a Genetic Code Expansion Cassette by Borrel, Guillaume, Gaci, Nadia, Peyret, Pierre, O'Toole, Paul W, Gribaldo, Simonetta, Brugère, Jean-François

“…Pyrrolysine (Pyl), the 22nd proteogenic amino acid, was restricted until recently to few organisms. Its translational use necessitates the presence of enzymes…”
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In vitro maintenance of a human proximal colon microbiota using the continuous fermentation system P-ECSIM by Feria-Gervasio, David, Denis, Sylvain, Alric, Monique, Brugère, Jean-François

“…Ethical and technical difficulties for in vivo studies on gut microbiotas argue for the development of alternative in vitro models: here, we describe a system…”
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The human gut chip "HuGChip", an explorative phylogenetic microarray for determining gut microbiome diversity at family level by Tottey, William, Denonfoux, Jeremie, Jaziri, Faouzi, Parisot, Nicolas, Missaoui, Mohiedine, Hill, David, Borrel, Guillaume, Peyretaillade, Eric, Alric, Monique, Harris, Hugh M B, Jeffery, Ian B, Claesson, Marcus J, O'Toole, Paul W, Peyret, Pierre, Brugère, Jean-François

“…Evaluating the composition of the human gut microbiota greatly facilitates studies on its role in human pathophysiology, and is heavily reliant on…”
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Three-stage continuous culture system with a self-generated anaerobia to study the regionalized metabolism of the human gut microbiota by Feria-Gervasio, David, Tottey, William, Gaci, Nadia, Alric, Monique, Cardot, Jean-Michel, Peyret, Pierre, Martin, Jean-François, Pujos, Estelle, Sébédio, Jean-Louis, Brugère, Jean-François

“…The technical and ethical difficulties in studying the gut microbiota in vivo warrant the development and improvement of in vitro systems able to simulate and…”
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Methanomethylophilus alvi gen. nov., sp. nov., a Novel Hydrogenotrophic Methyl-Reducing Methanogenic Archaea of the Order Methanomassiliicoccales Isolated from the Human Gut and Proposal of the Novel Family Methanomethylophilaceae fam. nov by Borrel, Guillaume, Fadhlaoui, Khaled, Ben Hania, Wajdi, Gaci, Nadia, Pehau-Arnaudet, Gérard, Chaudhary, Prem Prashant, Vandekerckove, Pascal, Ballet, Nathalie, Alric, Monique, O’Toole, Paul William, Fardeau, Marie-Laure, Ollivier, Bernard, Brugère, Jean-François

“…The methanogenic strain Mx-05T was isolated from the human fecal microbiome. A phylogenetic analysis based on the 16S rRNA gene and protein marker genes…”
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