Search Results - "Jean-Michel Constantin"

A Trial of Intraoperative Low-Tidal-Volume Ventilation in Abdominal Surgery by Futier, Emmanuel, Constantin, Jean-Michel, Paugam-Burtz, Catherine, Pascal, Julien, Eurin, Mathilde, Neuschwander, Arthur, Marret, Emmanuel, Beaussier, Marc, Gutton, Christophe, Lefrant, Jean-Yves, Allaouchiche, Bernard, Verzilli, Daniel, Leone, Marc, De Jong, Audrey, Bazin, Jean-Etienne, Pereira, Bruno, Jaber, Samir

“…Low-tidal-volume ventilation with positive end-expiratory pressure is the standard of care in acute respiratory distress syndrome. In this trial, the use of…”
Get full text

Liberal or Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome by Barrot, Loic, Asfar, Pierre, Mauny, Frederic, Winiszewski, Hadrien, Montini, Florent, Badie, Julio, Quenot, Jean-Pierre, Pili-Floury, Sebastien, Bouhemad, Belaid, Louis, Guillaume, Souweine, Bertrand, Collange, Olivier, Pottecher, Julien, Levy, Bruno, Puyraveau, Marc, Vettoretti, Lucie, Constantin, Jean-Michel, Capellier, Gilles

“…Patients with acute respiratory distress syndrome received conservative oxygen therapy or liberal oxygen therapy for 7 days. The trial was prematurely stopped…”
Get full text

High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure by Frat, Jean-Pierre, Thille, Arnaud W, Mercat, Alain, Girault, Christophe, Ragot, Stéphanie, Perbet, Sébastien, Prat, Gwénael, Boulain, Thierry, Morawiec, Elise, Cottereau, Alice, Devaquet, Jérôme, Nseir, Saad, Razazi, Keyvan, Mira, Jean-Paul, Argaud, Laurent, Chakarian, Jean-Charles, Ricard, Jean-Damien, Wittebole, Xavier, Chevalier, Stéphanie, Herbland, Alexandre, Fartoukh, Muriel, Constantin, Jean-Michel, Tonnelier, Jean-Marie, Pierrot, Marc, Mathonnet, Armelle, Béduneau, Gaëtan, Delétage-Métreau, Céline, Richard, Jean-Christophe M, Brochard, Laurent, Robert, René

“…Patients with acute hypoxemic respiratory failure were assigned to standard oxygen therapy, high-flow oxygen therapy, or noninvasive ventilation. The…”
Get full text

Phenotypes and personalized medicine in the acute respiratory distress syndrome by Matthay, Michael A., Arabi, Yaseen M., Siegel, Emily R., Ware, Lorraine B., Bos, Lieuwe D. J., Sinha, Pratik, Beitler, Jeremy R., Wick, Katherine D., Curley, Martha A. Q., Constantin, Jean-Michel, Levitt, Joseph E., Calfee, Carolyn S.

“…Although the acute respiratory distress syndrome (ARDS) is well defined by the development of acute hypoxemia, bilateral infiltrates and non-cardiogenic…”
Get full text

Analgesia and sedation in patients with ARDS by Chanques, Gerald, Constantin, Jean-Michel, Devlin, John W., Ely, E. Wesley, Fraser, Gilles L., Gélinas, Céline, Girard, Timothy D., Guérin, Claude, Jabaudon, Matthieu, Jaber, Samir, Mehta, Sangeeta, Langer, Thomas, Murray, Michael J., Pandharipande, Pratik, Patel, Bhakti, Payen, Jean-François, Puntillo, Kathleen, Rochwerg, Bram, Shehabi, Yahya, Strøm, Thomas, Olsen, Hanne Tanghus, Kress, John P.

“…Acute Respiratory Distress Syndrome (ARDS) is one of the most demanding conditions in an Intensive Care Unit (ICU). Management of analgesia and sedation in…”
Get full text

Evolving outcomes of extracorporeal membrane oxygenation support for severe COVID-19 ARDS in Sorbonne hospitals, Paris by Schmidt, Matthieu, Langouet, Elise, Hajage, David, James, Sarah Aissi, Chommeloux, Juliette, Bréchot, Nicolas, Barhoum, Petra, Lefèvre, Lucie, Troger, Antoine, de Chambrun, Marc Pineton, Hékimian, Guillaume, Luyt, Charles-Edouard, Dres, Martin, Constantin, Jean-Michel, Fartoukh, Muriel, Leprince, Pascal, Lebreton, Guillaume, Combes, Alain

“…Background Extracorporeal membrane oxygenation (ECMO) was frequently used to treat patients with severe coronavirus disease-2019 (COVID-19)-associated acute…”
Get full text

Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial by Jaber, Samir, Paugam, Catherine, Futier, Emmanuel, Lefrant, Jean-Yves, Lasocki, Sigismond, Lescot, Thomas, Pottecher, Julien, Demoule, Alexandre, Ferrandière, Martine, Asehnoune, Karim, Dellamonica, Jean, Velly, Lionel, Abback, Paër-Sélim, de Jong, Audrey, Brunot, Vincent, Belafia, Fouad, Roquilly, Antoine, Chanques, Gérald, Muller, Laurent, Constantin, Jean-Michel, Bertet, Helena, Klouche, Kada, Molinari, Nicolas, Jung, Boris, Jaber, Samir, de Jong, Audrey, Belafia, Fouad, Chanques, Gérald, Monnin, Marion, Delay, Jean-Marc, Cissé, Moussa, Geniez, Marie, Conseil, Matthieu, Souche, Bruno, Paugam, Catherine, Abback, Paër-Sélim, Futier, Emmanuel, Constantin, Jean Michel, Lefrant, Jean-Yves, Muller, Laurent, Lasocki, Sigismond, Lescot, Thomas, Pottecher, Julien, Noll, Eric, Demoule, Alexandre, Morawiec, Elise, Ferrandière, Martine, Asehnoune, Karim, Roquilly, Antoine, Dellamonica, Jean, Robert, Alexandre, Velly, Lionel, Triglia, Thibaut, Brunot, Vincent, Molinari, Nicolas, Mechati, Malika, Arnal, Jean-Michel, Durand-Gasselin, Jacques, Demoly, Didier, Hraiech, Sami, Papazian, Laurent, Gilles, Vincent, Rimmelé, Thomas, Riu, Béatrice, Cougot, Pierre, Fourcade, Olivier, Seguin, Philippe, Charbit, Jonathan, Capdevila, Xavier, Leone, Marc, Zieleskiewicz, Laurent, Ichai, Carole, Orban, Jean Christophe, Darmon, Michael, Azoulay, Elie, Lemiale, Virginie, Zafrani, Lara, Debbat, Karim, Mimoz, Oliver, Guérin, Claude, Kipnis, Eric

“…Acute acidaemia is frequently observed during critical illness. Sodium bicarbonate infusion for the treatment of severe metabolic acidaemia is a possible…”
Get full text

Incidence of and risk factors for severe cardiovascular collapse after endotracheal intubation in the ICU: a multicenter observational study by Perbet, Sebastien, De Jong, Audrey, Delmas, Julie, Futier, Emmanuel, Pereira, Bruno, Jaber, Samir, Constantin, Jean-Michel

“…Severe cardiovascular collapse (CVC) is a life-threatening complication after emergency endotracheal intubation (ETI) in the ICU. Many factors may interact…”
Get full text

Use of volatile agents for sedation in the intensive care unit: A national survey in France by Blondonnet, Raiko, Quinson, Audrey, Lambert, Céline, Audard, Jules, Godet, Thomas, Zhai, Ruoyang, Pereira, Bruno, Futier, Emmanuel, Bazin, Jean-Etienne, Constantin, Jean-Michel, Jabaudon, Matthieu

“…Current intensive care unit (ICU) sedation guidelines recommend strategies using non-benzodiazepine sedatives. This survey was undertaken to explore inhaled…”
Get full text

Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome by Papazian, Laurent, Forel, Jean-Marie, Gacouin, Arnaud, Penot-Ragon, Christine, Perrin, Gilles, Loundou, Anderson, Jaber, Samir, Arnal, Jean-Michel, Perez, Didier, Seghboyan, Jean-Marie, Constantin, Jean-Michel, Courant, Pierre, Lefrant, Jean-Yves, Guérin, Claude, Prat, Gwenaël, Morange, Sophie, Roch, Antoine

“…The investigators induced muscle paralysis in patients with the acute respiratory distress syndrome (ARDS) by administering a neuromuscular blocking agent,…”
Get full text

RAGE inhibition reduces acute lung injury in mice by Blondonnet, Raiko, Audard, Jules, Belville, Corinne, Clairefond, Gael, Lutz, Jean, Bouvier, Damien, Roszyk, Laurence, Gross, Christelle, Lavergne, Marilyne, Fournet, Marianne, Blanchon, Loic, Vachias, Caroline, Damon-Soubeyrand, Christelle, Sapin, Vincent, Constantin, Jean-Michel, Jabaudon, Matthieu

“…The receptor for advanced glycation end-products (RAGE) is involved in inflammatory response during acute respiratory distress syndrome (ARDS). Growing body of…”
Get full text

Use of volatile anesthetics for sedation in the ICU during the COVID-19 pandemic: A national survey in France (VOL'ICU 2 study) by Blondonnet, Raiko, Balde, Aissatou, Zhai, Ruoyang, Pereira, Bruno, Futier, Emmanuel, Bazin, Jean-Etienne, Godet, Thomas, Constantin, Jean-Michel, Lambert, Céline, Jabaudon, Matthieu

“…The COVID-19 pandemic has increased the number of patients in ICUs leading to a worldwide shortage of the intravenous sedative agents obligating physicians to…”
Get full text

Noninvasive respiratory support in the hypoxaemic peri-operative/periprocedural patient: a joint ESA/ESICM guideline by Leone, Marc, Einav, Sharon, Chiumello, Davide, Constantin, Jean-Michel, De Robertis, Edoardo, De Abreu, Marcelo Gama, Gregoretti, Cesare, Jaber, Samir, Maggiore, Salvatore Maurizio, Pelosi, Paolo, Sorbello, Massimiliano, Afshari, Arash

“…Hypoxaemia is a potential life-threatening yet common complication in the peri-operative and periprocedural patient (e.g. during an invasive procedure at risk…”
Get full text

Pathological Implications of Receptor for Advanced Glycation End-Product (AGER) Gene Polymorphism by Sapin, Vincent, Blanchon, Loïc, Gross, Christelle, Blondonnet, Raiko, Belville, Corinne, Creveaux, Isabelle, Jabaudon, Matthieu, Serveaux-Dancer, Marine, Constantin, Jean-Michel

“…The receptor for advanced glycation end-products (RAGE) is a cell surface transmembrane multiligand receptor, encoded by the AGER gene. RAGE presents many…”
Get full text

Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress by Soummer, Alexis, Perbet, Sébastien, Brisson, Hélène, Arbelot, Charlotte, Constantin, Jean-Michel, Lu, Qin, Rouby, Jean-Jacques, Bouberima, Mohammed, Roszyk, Laurence, Bouhemad, Bélaïd, Monsel1, Antoine, Do, Chung Hi, Saleh, Mohamed, Vezinet, Corinne, Bodin, Liliane, Lemanach, Yannick, Devilliers, Catherine, Bazin, Jean-Etienne, Cayot-Constantin, Sophie, Sapin, Vincent, Jabaudon, Matthieu, Bulpa, Pierre

“…OBJECTIVE:Postextubation distress after a successful spontaneous breathing trial is associated with increased morbidity and mortality. Predicting…”
Get full text

Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data by Jabaudon, Matthieu, Blondonnet, Raiko, Pereira, Bruno, Cartin-Ceba, Rodrigo, Lichtenstern, Christoph, Mauri, Tommaso, Determann, Rogier M., Drabek, Tomas, Hubmayr, Rolf D., Gajic, Ognjen, Uhle, Florian, Coppadoro, Andrea, Pesenti, Antonio, Schultz, Marcus J., Ranieri, Marco V., Brodska, Helena, Mrozek, Ségolène, Sapin, Vincent, Matthay, Michael A., Constantin, Jean-Michel, Calfee, Carolyn S.

“…Purpose The soluble receptor for advanced glycation end-products (sRAGE) is a marker of lung epithelial injury and alveolar fluid clearance (AFC), with…”
Get full text

Soluble Receptor for Advanced Glycation End-Products Predicts Impaired Alveolar Fluid Clearance in Acute Respiratory Distress Syndrome by Jabaudon, Matthieu, Blondonnet, Raiko, Roszyk, Laurence, Bouvier, Damien, Audard, Jules, Clairefond, Gael, Fournier, Mathilde, Marceau, Geoffroy, Déchelotte, Pierre, Pereira, Bruno, Sapin, Vincent, Constantin, Jean-Michel

“…Levels of the soluble form of the receptor for advanced glycation end-products (sRAGE) are elevated during acute respiratory distress syndrome (ARDS) and…”
Get full text

Time course of fluid responsiveness in sepsis: the fluid challenge revisiting (FCREV) study by Roger, Claire, Zieleskiewicz, Laurent, Demattei, Christophe, Lakhal, Karim, Piton, Gael, Louart, Benjamin, Constantin, Jean-Michel, Chabanne, Russell, Faure, Jean-Sébastien, Mahjoub, Yazine, Desmeulles, Isabelle, Quintard, Hervé, Lefrant, Jean-Yves, Muller, Laurent

“…Fluid challenge (FC) is one of the most common practices in Intensive Care Unit (ICU). The present study aimed to evaluate whether echocardiographic assessment…”
Get full text

Use of brain diffusion tensor imaging for the prediction of long-term neurological outcomes in patients after cardiac arrest: a multicentre, international, prospective, observational, cohort study by Velly, Lionel, Perlbarg, Vincent, Boulier, Thomas, Adam, Nicolas, Delphine, Sebastien, Luyt, Charles-Edouard, Battisti, Valentine, Torkomian, Gregory, Arbelot, Charlotte, Chabanne, Russell, Jean, Betty, Di Perri, Carol, Laureys, Steven, Citerio, Giuseppe, Vargiolu, Alessia, Rohaut, Benjamin, Bruder, Nicolas, Girard, Nadine, Silva, Stein, Cottenceau, Vincent, Tourdias, Thomas, Coulon, Olivier, Riou, Bruno, Naccache, Lionel, Gupta, Rajiv, Benali, Habib, Galanaud, Damien, Puybasset, Louis, Constantin, Jean-Michel, Chastre, Jean, Amour, Julien, Vezinet, Corine, Rouby, Jean-Jacques, Raux, Mathieu, Langeron, Olivier, Degos, Vincent, Bolgert, Francis, Weiss, Nicolas, Similowski, Thomas, Demoule, Alexandre, Duguet, Alexandre, Tollard, Eleonore, Veber, Benoit, Lotterie, Jean-Albert, SANCHEZ-PENA, Paola, Génestal, Michèle, Patassini, Mirko

“…Prediction of neurological outcome after cardiac arrest is a major challenge. The aim of this study was to assess whether quantitative whole-brain white matter…”
Get full text

De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial by Leone, Marc, Bechis, Carole, Baumstarck, Karine, Lefrant, Jean-Yves, Albanèse, Jacques, Jaber, Samir, Lepape, Alain, Constantin, Jean-Michel, Papazian, Laurent, Bruder, Nicolas, Allaouchiche, Bernard, Bézulier, Karine, Antonini, François, Textoris, Julien, Martin, Claude

“…Background In patients with severe sepsis, no randomized clinical trial has tested the concept of de-escalation of empirical antimicrobial therapy. This study…”
Get full text