Search Results - "Je Kyung Seong"

The anti-diabetic effects of NAG-1/GDF15 on HFD/STZ-induced mice by Lertpatipanpong, Pattawika, Lee, Jaehak, Kim, Ilju, Eling, Thomas, Oh, Seung Yeon, Seong, Je Kyung, Baek, Seung Joon

“…Nonsteroidal anti-inflammatory drug-activated gene-1 (NAG-1) plays a role in various diseases. Here, the anti-diabetic effects of NAG-1 were evaluated using a…”
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Fas mutation reduces obesity by increasing IL-4 and IL-10 expression and promoting white adipose tissue browning by Choi, Eun Wha, Lee, Minjae, Song, Ji Woo, Kim, Kyeongdae, Lee, Jungmin, Yang, Jehoon, Lee, Seo Hyun, Kim, Il Yong, Choi, Jae-Hoon, Seong, Je Kyung

“…Brown adipose tissue generates heat via the mitochondrial uncoupling protein UCP1 to protect against obesity and hypothermia. Fas mutant MRL/lpr mice exhibit a…”
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Nuclear receptor PPARγ-regulated monoacylglycerol O-acyltransferase 1 (MGAT1) expression is responsible for the lipid accumulation in diet-induced hepatic steatosis by Lee, Yoo Jeong, Ko, Eun Hee, Kim, Ji Eun, Kim, Eunha, Lee, Hyemin, Choi, Hyeonjin, Yu, Jung Hwan, Kim, Hyo Jung, Seong, Je-Kyung, Kim, Kyung-Sup, Kim, Jae-woo

“…Recently, hepatic peroxisome proliferator-activated receptor (PPAR)γ has been implicated in hepatic lipid accumulation. We found that the C3H mouse strain does…”
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Overexpression of translationally controlled tumor protein ameliorates metabolic imbalance and increases energy expenditure in mice by Jeon, Yejin, Choi, Ji-Young, Jang, Eun-Hwa, Seong, Je Kyung, Lee, Kyunglim

“…Background/Objectives Translationally controlled tumor protein (TCTP) exhibits numerous biological functions. It has been shown to be involved in the…”
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Chronic type 2 diabetes reduces the integrity of the blood-brain barrier by reducing tight junction proteins in the hippocampus by YOO, Dae Young, YIM, Hee Sun, JUNG, Hyo Young, NAM, Sung Min, KIM, Jong Whi, CHOI, Jung Hoon, SEONG, Je Kyung, YOON, Yeo Sung, KIM, Dae Won, HWANG, In Koo

“…In the present study, we investigated the effects of type 2 diabetes-induced hyperglycemia on the integrity of the blood–brain barrier and tight junction…”
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Single-cell analysis of gastric pre-cancerous and cancer lesions reveals cell lineage diversity and intratumoral heterogeneity by Kim, Jihyun, Park, Charny, Kim, Kwang H., Kim, Eun Hye, Kim, Hyunki, Woo, Jong Kyu, Seong, Je Kyung, Nam, Ki Taek, Lee, Yong Chan, Cho, Soo Young

“…Single-cell transcriptomic profiles analysis has proposed new insights for understanding the behavior of human gastric cancer (GC). GC offers a unique model of…”
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Single-cell transcriptomic analysis reveals dynamic activation of cellular signaling pathways regulating beige adipogenesis by Kyung, Dong Soo, Lee, Eunmin, Chae, Sehyun, Son, Yeonho, Moon, Ye-Jin, Hwang, Daehee, Kim, Jong Kyoung, Lee, Yun-Hee, Seong, Je Kyung

“…PDGFRA+ cells have been identified as adipocyte stem cells (ASCs) that differentiate into beige adipocytes in white adipose tissue (WAT) following thermogenic…”
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HBx induces hypomethylation of distal intragenic CpG islands required for active expression of developmental regulators by Lee, Sun-Min, Lee, Young-gun, Bae, Jae-Bum, Choi, Jung Kyoon, Tayama, Chiharu, Hata, Kenichiro, Yun, Yungdae, Seong, Je-Kyung, Kim, Young-Joon

“…Epigenetic alterations caused by viral oncoproteins are strong initiation factors for cancer development, but their mechanisms are largely unknown. To identify…”
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YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity by Lee, Gwan-Jun, Kim, Youn Ju, Park, Bongju, Yim, Sujin, Park, Chansang, Roh, Hyunsoo, Moon, Yunwon, Seong, Je Kyung, Park, Hyunsung

“…Wnt5a, a prototypic non-canonical Wnt, is an inflammatory factor elevated in the sera of obese humans and mice. In the present study, fat-specific knockout of…”
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Molybdate Attenuates Lipid Accumulation in the Livers of Mice Fed a Diet Deficient in Methionine and Choline by Lee, Seungwoo, Nam, Ki-Hoan, Seong, Je Kyung, Ryu, Doug-Young

“…Both lipid accumulation and oxidative stress are major pathologic contributors to the development of hepatic steatosis. Treatment with molybdate reduces…”
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Development of CIDEA reporter mouse model and its application for screening thermogenic drugs by Son, Yeonho, Choi, Cheoljun, Song, Cheol, Im, Hyeonyeong, Cho, Yoon Keun, Son, Ju Seung, Joo, Sungug, Joh, Yoonjoe, Lee, Young Jae, Seong, Je Kyung, Lee, Yun-Hee

“…Cell death-inducing DNA fragmentation factor-like effector A (CIDEA) is a lipid droplet-associated protein and is a known marker of the thermogenic capacity of…”
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Mettl14 mutation restrains liver regeneration by attenuating mitogens derived from non-parenchymal liver cells by Insook, Yang, Seung Yeon, Oh, Suin, Jang, Il Yong, Kim, You Me, Sung, Je Kyung, Seong

“…Liver regeneration is a well-known systemic homeostatic phenomenon. The N 6 -methyladenosine (m 6 A) modification pathway has been associated with liver…”
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Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue by Son, Yeonho, Cho, Yoon Keun, Saha, Abhirup, Kwon, Hyun-Jung, Park, Ji-Hyun, Kim, Minsu, Jung, Young-Suk, Kim, Sang-Nam, Choi, Cheoljun, Seong, Je-Kyung, Burl, Rayanne B., Granneman, James G., Lee, Yun-Hee

“…Beclin1 is a core molecule of the macroautophagy machinery. Although dysregulation of macroautophagy is known to be involved in metabolic disorders, the…”
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Development of transgenic models susceptible and resistant to SARS-CoV-2 infection in FVB background mice by Seo, Sun-Min, Son, Jae Hyung, Lee, Ji-Hun, Kim, Na-Won, Yoo, Eun-Seon, Kang, Ah-Reum, Jang, Ji Yun, On, Da In, Noh, Hyun Ah, Yun, Jun-Won, Park, Jun Won, Choi, Kang-Seuk, Lee, Ho-Young, Shin, Jeon-Soo, Seo, Jun-Young, Nam, Ki Taek, Lee, Ho, Seong, Je Kyung, Choi, Yang-Kyu

“…Coronavirus disease (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is currently spreading globally. To overcome the…”
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Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice by Kim, Sang-Nam, Akindehin, Seun, Kwon, Hyun-Jung, Son, Yeon-Ho, Saha, Abhirup, Jung, Young-Suk, Seong, Je-Kyung, Lim, Kyung-Min, Sung, Jong-Hyuk, Maddipati, Krishna Rao, Lee, Yun-Hee

“…15-lipoxygenase is involved in the generation of specialized pro-resolving lipid mediators that play essential roles in resolution and inflammatory responses…”
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Asian Mouse Mutagenesis Resource Association (AMMRA): mouse genetics and laboratory animal resources in the Asia Pacific by Chin, Hsian-Jean, Dobbie, Michael S., Gao, Xiang, Hennessy, James E., Nam, Ki-Hoan, Seong, Je Kyung, Shiroishi, Toshihiko, Takeo, Toru, Yoshiki, Atsushi, Zao, Jing, Wang, Chi-Kuang Leo

“…The Asian Mouse Mutagenesis Resource Association (AMMRA) is a non-profit organization consisting of major resource and research institutions with rodent…”
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SARS-CoV-2 infection engenders heterogeneous ribonucleoprotein interactions to impede translation elongation in the lungs by Kim, Junsoo, Youn, Daehwa, Choi, Seunghoon, Lee, Youn Woo, Sumberzul, Dulguun, Yoon, Jeongeun, Lee, Hanju, Bae, Jong Woo, Noh, Hyuna, On, Dain, Hong, Seung-Min, An, Se-Hee, Jang, Hui Jeong, Kim, Seo Yeon, Kim, Young Been, Hwang, Ji-Yeon, Lee, Hyo-Jung, Bin Kim, Hong, Park, Jun Won, Yun, Jun-Won, Shin, Jeon-Soo, Seo, Jun-Young, Nam, Ki Taek, Choi, Kang-Seuk, Lee, Ho-Young, Chang, Hyeshik, Seong, Je Kyung, Cho, Jun

“…Translational regulation in tissue environments during in vivo viral pathogenesis has rarely been studied due to the lack of translatomes from virus-infected…”
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Neural regulation of energy and bone homeostasis by the synaptic adhesion molecule Calsyntenin-3 by Kim, Sung-Jin, Jeong, Yong Taek, Jeong, Se Rok, Park, Munsu, Go, Hye Sun, Kim, Mi Young, Seong, Je Kyung, Kim, Ki Woo, Seo, Jeong Taeg, Kim, Chul Hoon, Lee, Ji Hyun, Moon, Seok Jun

“…Neuronal regulation of energy and bone metabolism is important for body homeostasis. Many studies have emphasized the importance of synaptic adhesion molecules…”
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UCP2 KO mice exhibit ameliorated obesity and inflammation induced by high-fat diet feeding by Kim, Do Hyun, Kim, Hye Jin, Seong, Je Kyung

“…Uncoupling protein 2 (Ucp2) was first introduced as a member of Uncoupling protein family and a regulator of ROS formation; however, its role in adipose tissue…”
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Comprehensive identification of novel post-translational modifications in cellular peroxiredoxin 6 by Jeong, Jaeho, Kim, Yunghee, Kyung Seong, Je, Lee, Kong-Joo

“…Peroxiredoxin 6 (PRDX6), a 1‐Cys peroxiredoxin, is a bifunctional enzyme acting both as a glutathione peroxidase and a phospholipase A2. However, the…”
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