Search Results - "Jayo, Asier"

Local dimensionality determines imaging speed in localization microscopy by Fox-Roberts, Patrick, Marsh, Richard, Pfisterer, Karin, Jayo, Asier, Parsons, Maddy, Cox, Susan

“…Localization microscopy allows biological samples to be imaged at a length scale of tens of nanometres. Live-cell super-resolution imaging is rare, as it is…”
Get full text

High prevalence of intrathecal IgA synthesis in multiple sclerosis patients by Muñoz, Úrsula, Sebal, Cristina, Escudero, Esther, García Sánchez, Maria Isabel, Urcelay, Elena, Jayo, Asier, Arroyo, Rafael, García-Martínez, Maria A., Álvarez-Lafuente, Roberto, Sádaba, María C.

“…The detection of intrathecal IgA synthesis (IAS) in multiple sclerosis (MS) could be underestimated. To assess it, we develop a highly sensitive assay based on…”
Get full text

A direct interaction between fascin and microtubules contributes to adhesion dynamics and cell migration by Villari, Giulia, Jayo, Asier, Zanet, Jennifer, Fitch, Briana, Serrels, Bryan, Frame, Margaret, Stramer, Brian M, Goult, Benjamin T, Parsons, Maddy

“…Fascin is an actin-binding and bundling protein that is highly upregulated in most epithelial cancers. Fascin promotes cell migration and adhesion dynamics in…”
Get full text

Nuclear fascin regulates cancer cell survival by Lawson, Campbell D, Peel, Samantha, Jayo, Asier, Corrigan, Adam, Iyer, Preeti, Baxter Dalrymple, Mabel, Marsh, Richard J, Cox, Susan, Van Audenhove, Isabel, Gettemans, Jan, Parsons, Maddy

“…Fascin is an important regulator of F-actin bundling leading to enhanced filopodia assembly. Fascin is also overexpressed in most solid tumours where it…”
Get full text

A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability by Jayo, Asier, Parsons, Maddy, Adams, Josephine C

“…Fascin-1 is an actin crosslinking protein that is important for the assembly of cell protrusions in neurons, skeletal and smooth muscle, fibroblasts, and…”
Get full text

L718P mutation in the membrane-proximal cytoplasmic tail of β3 promotes abnormal αIIbβ3 clustering and lipid microdomain coalescence, and associates with a thrombasthenia-like phenotype by JAYO, Asier, CONDE, Isabel, LASTRES, Pedro, MARTINEZ, Constantino, RIVERA, José, VICENTE, Vicente, GONZALEZ-MANCHON, Consuelo

“…Background Support for the role of transmembrane and membrane-proximal domains of αIIbβ3 integrin in the maintenance of receptor low affinity comes from…”
Get full text

Fascin: A key regulator of cytoskeletal dynamics by Jayo, Asier, Parsons, Maddy

“…Fascin is a 55kDa actin-bundling protein and is an important regulatory element in the maintenance and stability of parallel bundles of filamentous actin in a…”
Get full text

Involvement of ERK1/2, p38 and PI3K in megakaryocytic differentiation of K562 cells by Conde, Isabel, Pabón, Dina, Jayo, Asier, Lastres, Pedro, González-Manchón, Consuelo

“…Megakaryocytic differentiation of myelogenous leukemia cell lines induced by a number of chemical compounds mimics, in part, the physiological process that…”
Get full text

Fascin Regulates Nuclear Movement and Deformation in Migrating Cells by Jayo, Asier, Malboubi, Majid, Antoku, Susumu, Chang, Wakam, Ortiz-Zapater, Elena, Groen, Christopher, Pfisterer, Karin, Tootle, Tina, Charras, Guillaume, Gundersen, Gregg G., Parsons, Maddy

“…Fascin is an F-actin-bundling protein shown to stabilize filopodia and regulate adhesion dynamics in migrating cells, and its expression is correlated with…”
Get full text

Control of nuclear organization by F-actin binding proteins by Pfisterer, Karin, Jayo, Asier, Parsons, Maddy

“…The regulation of nuclear shape and deformability is a key factor in controlling diverse events from embryonic development to cancer cell metastasis, but the…”
Get full text

Fascin promotes filopodia formation independent of its role in actin bundling by Zanet, Jennifer, Jayo, Asier, Plaza, Serge, Millard, Tom, Parsons, Maddy, Stramer, Brian

“…Fascin is an evolutionarily conserved actin-binding protein that plays a key role in forming filopodia. It is widely thought that this function involves fascin…”
Get full text

Imaging of cell adhesion events in 3D matrix environments by Jayo, Asier, Parsons, Maddy

“…Cell adhesion plays an essential role in development and homeostasis, but is also a key regulator of many diseases such as cancer and immune dysfunction…”
Get full text

An open access microfluidic device for the study of the physical limits of cancer cell deformation during migration in confined environments by Malboubi, Majid, Jayo, Asier, Parsons, Maddy, Charras, Guillaume

“…[Display omitted] •A microfluidic device to study cell and nuclear deformation during translocation.•Adherent cells protrude their cytoplasm regardless of the…”
Get full text

Microfluidic Devices for Examining the Physical Limits of Migration in Confined Environments by Malboubi, Majid, Jayo, Asier, Parsons, Maddy, Charras, Guillaume

“…Cell migration plays a key role in many physiological and pathological conditions during which cells migrate primarily in the 3D environments formed by…”
Get more information

Prostaglandins regulate nuclear localization of Fascin and its function in nucleolar architecture by Groen, Christopher M, Jayo, Asier, Parsons, Maddy, Tootle, Tina L

“…Fascin, a highly conserved actin-bundling protein, localizes and functions at new cellular sites in both Drosophila and multiple mammalian cell types. During…”
Get full text

Corrigendum to “Fascin: A key regulator of cytoskeletal dynamics” [Int. J. Biochem. Cell Biol. 42 (10) (2010) 1614–1617] by Jayo, Asier, Parsons, Maddy

Get full text

The first World Cell Race by Maiuri, Paolo, Terriac, Emmanuel, Paul-Gilloteaux, Perrine, Vignaud, Timothée, McNally, Krista, Onuffer, James, Thorn, Kurt, Nguyen, Phuong A., Georgoulia, Nefeli, Soong, Daniel, Jayo, Asier, Beil, Nina, Beneke, Jürgen, Hong Lim, Joleen Chooi, Pei-Ying Sim, Chloe, Chu, Yeh-Shiu, Jiménez-Dalmaroni, Andrea, Joanny, Jean-François, Thiery, Jean-Paul, Erfle, Holger, Parsons, Maddy, Mitchison, Timothy J., Lim, Wendell A., Lennon-Duménil, Ana-Maria, Piel, Matthieu, Théry, Manuel

“…Motility is a common property of animal cells. Cell motility is required for embryogenesis [1], tissue morphogenesis [2] and the immune response [3] but is…”
Get full text

Possible role for cellular FXIII in monocyte-derived dendritic cell motility by Jayo, Asier, Conde, Isabel, Lastres, Pedro, Jiménez-Yuste, Victor, González-Manchón, Consuelo

“…The A subunit of plasma factor XIII (FXIII-A) is thought to function as an intracellular transglutaminase (TG) in the monocyte/macrophage lineage to regulate…”
Get full text

Hypodysfibrinogenemia causing mild bleeding and thrombotic complications in a compound heterozygote of AalphaIVS4+1G>T mutation and Aalpha4841delC truncation (Aalpha(Perth)) by Jayo, Asier, Arnold, Erin, González-Manchón, Consuelo, Green, David, Lord, Susan T

Get more information

The first World Cell Race by Maiuri, Paolo, Terriac, Emmanuel, Paul-Gilloteaux, Perrine, Vignaud, Timothée, McNally, Krista, Onuffer, James, Thorn, Kurt, Nguyen, Phuong A., Georgoulia, Nefeli, Soong, Daniel, Jayo, Asier, Beil, Nina, Beneke, Jürgen, Lim, Joleen Chooi Hong, Sim, Chloe Pei-Ying, Chu, Yeh-Shiu, Jiménez-Dalmaroni, Andrea, Joanny, Jean-François, Thiery, Jean-Paul, Erfle, Holger, Parsons, Maddy, Mitchison, Timothy J., Lim, Wendell A., Lennon-Duménil, Ana-Maria, Piel, Matthieu, Théry, Manuel

Get full text