Search Results - "Jayasimhan, Abhirup"

Dietary SCFAs, IL-22, and GFAP: The Three Musketeers in the Gut-Neuro-Immune Network in Type 1 Diabetes by Jayasimhan, Abhirup, Mariño, Eliana

“…Microbial metabolites have a profound effect on the development of type 1 diabetes (T1D). The cross-talk between the gut microbiota, the nervous system, and…”
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Early Depletion of Neutrophils Reduces Retinal Inflammation and Neovascularization in Mice with Oxygen-Induced Retinopathy by Deliyanti, Devy, Suphapimol, Varaporn, Ang, Phoebe, Tang, Xiuying, Jayasimhan, Abhirup, Wilkinson-Berka, Jennifer L

“…Retinal inflammation is a central feature of ocular neovascular diseases such as diabetic retinopathy and retinopathy of prematurity, but the contribution of…”
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Advances in our understanding of the pathophysiology of Type 1 diabetes: lessons from the NOD mouse by Jayasimhan, Abhirup, Mansour, Kristy P, Slattery, Robyn M

“…T1D (Type 1 diabetes) is an autoimmune disease caused by the immune-mediated destruction of pancreatic β-cells. Studies in T1D patients have been limited by…”
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PS-BPB06-8: THE NON-STEROIDAL MINERALOCORTICOID RECEPTOR ANTAGONIST, FINERENONE, REDUCES VASCULAR PATHOLOGY AND INFLAMMATION IN PRE-CLINICAL DIABETIC RETINOPATHY by Jerome, Jack Ryan, Suphapimol, Vara, Delayanti, Devy, Jayasimhan, Abhirup, Kolkhof, Peter, Wilkinson-Berka, Jennifer

“…Objective: Diabetic retinopathy is the leading cause of vision loss in the working population across the globe. Diabetes has devastating effects on the retinal…”
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Pancreatic ductal cell antigens are important in the development of invasive insulitis in Non-Obese Diabetic mice by Jayasimhan, Abhirup, Ellis, Darcy P., Ziegler, Alexandra I., Slattery, Robyn M.

“…Type 1 Diabetes (T1D) is an autoimmune disease in which insulin producing beta cells of the pancreas are selectively destroyed. Glial Fibrillary Acidic Protein…”
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The CD19 signalling molecule is elevated in NOD mice and controls type 1 diabetes development by Ziegler, Alexandra I., Le Page, Melanie A., Maxwell, Mhairi J., Stolp, Jessica, Guo, Haoyao, Jayasimhan, Abhirup, Hibbs, Margaret L., Santamaria, Pere, Miller, Jacques F., Plebanski, Magdalena, Silveira, Pablo A., Slattery, Robyn M.

“…Aims/hypothesis Type 1 diabetes is characterised by early peri-islet insulitis and insulin autoantibodies, followed by invasive insulitis and beta cell…”
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