Search Results - "Jayakumar, Rojashree"

Cryopreservation of cerebrospinal fluid cells preserves the transcriptional landscape for single-cell analysis by Kodali, Mahesh Chandra, Antone, Jerry, Alsop, Eric, Jayakumar, Rojashree, Parikh, Khushi, Chiot, Aude, Sanchez-Molina, Paula, Ajami, Bahareh, Arnold, Steven E, Jensen, Kendall, Das, Sudeshna, Weinberg, Marc S

“…Cerebrospinal fluid (CSF) matrix biomarkers have become increasingly valuable surrogate markers of neuropsychiatric diseases in research and clinical practice…”
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Alzheimer DataLENS: An Open Data Analytics Portal for Alzheimer's Disease Research by Noori, Ayush, Jayakumar, Rojashree, Moturi, Vaishnavi, Li, Zhaozhi, Liu, Rongxin, Serrano-Pozo, Alberto, Hyman, Bradley T, Das, Sudeshna

“…Recent Alzheimer's disease (AD) discoveries are increasingly based on studies from a variety of omics technologies on large cohorts. Currently, there is no…”
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Endothelial Cells Are Heterogeneous in Different Brain Regions and Are Dramatically Altered in Alzheimer's Disease by Bryant, Annie, Li, Zhaozhi, Jayakumar, Rojashree, Serrano-Pozo, Alberto, Woost, Benjamin, Hu, Miwei, Woodbury, Maya E, Wachter, Astrid, Lin, Gen, Kwon, Taekyung, Talanian, Robert V, Biber, Knut, Karran, Eric H, Hyman, Bradley T, Das, Sudeshna, Bennett, Rachel E

“…Vascular endothelial cells play an important role in maintaining brain health, but their contribution to Alzheimer's disease (AD) is obscured by limited…”
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GFAP Upregulation by Astrocytes May Attenuate Phospho‐Tau Levels in a Tauopathy Mouse Model by Muñoz‐Castro, Clara, Healey, Molly A., Jaisa‐Aad, Methasit, Jayakumar, Rojashree, Alla, Srinija, Kashlan, Zane D., Noori, Ayush, Fan, Zhanyun, Calvo‐Rodriguez, Maria, Das, Sudeshna, Hudry, Eloise, Hyman, Bradley T., Serrano‐Pozo, Alberto

“…Background Astrocytes react to amyloid‐β plaques and phospho‐tau (pTau) neurofibrillary tangles in the Alzheimer’s disease brain but their net effect on these…”
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Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease by Serrano-Pozo, Alberto, Li, Huan, Li, Zhaozhi, Muñoz-Castro, Clara, Jaisa-aad, Methasit, Healey, Molly A., Welikovitch, Lindsay A., Jayakumar, Rojashree, Bryant, Annie G., Noori, Ayush, Connors, Theresa R., Hu, Miwei, Zhao, Karen, Liao, Fan, Lin, Gen, Pastika, Timothy, Tamm, Joseph, Abdourahman, Aicha, Kwon, Taekyung, Bennett, Rachel E., Woodbury, Maya E., Wachter, Astrid, Talanian, Robert V., Biber, Knut, Karran, Eric H., Hyman, Bradley T., Das, Sudeshna

“…Astrocytes are crucial to brain homeostasis, yet their changes along the spatiotemporal progression of Alzheimer's disease (AD) neuropathology remain…”
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Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease by Agra Almeida Quadros, Ana Rita, Li, Zhaozhi, Wang, Xue, Ndayambaje, I. Sandra, Aryal, Sandeep, Ramesh, Nandini, Nolan, Matthew, Jayakumar, Rojashree, Han, Yi, Stillman, Hannah, Aguilar, Corey, Wheeler, Hayden J., Connors, Theresa, Lopez-Erauskin, Jone, Baughn, Michael W., Melamed, Ze’ev, Beccari, Melinda S., Olmedo Martínez, Laura, Canori, Michael, Lee, Chao-Zong, Moran, Laura, Draper, Isabelle, Kopin, Alan S., Oakley, Derek H., Dickson, Dennis W., Cleveland, Don W., Hyman, Bradley T., Das, Sudeshna, Ertekin-Taner, Nilüfer, Lagier-Tourenne, Clotilde

“…Nuclear clearance and cytoplasmic accumulations of the RNA-binding protein TDP-43 are pathological hallmarks in almost all patients with amyotrophic lateral…”
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Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease by Serrano‐Pozo, Alberto, Li, Zhaozhi, Woodbury, Maya E., Muñoz‐Castro, Clara, Wachter, Astrid, Jayakumar, Rojashree, Bryant, Annie G, Noori, Ayush, Welikovitch, Lindsay A., Hu, Miwei, Lin, Gen, Pastika, Timothy, Tamm, Joseph A., Abdourahman, Aicha, Kwon, Taekyung, Bennett, Rachel E, Talanian, Robert V., Biber, Knut, Karran, Eric H, Hyman, Bradley T., Das, Sudeshna

“…Background Alzheimer’s disease (AD) is defined by widespread accumulation of Ab plaques and phospho‐tau neurofibrillary tangles throughout the brain, with the…”
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