Search Results - "Jayakody, Buddhika"

A Blunted GPR183/Oxysterol Axis During Dysglycemia Results in Delayed Recruitment of Macrophages to the Lung During Mycobacterium tuberculosis Infection by Ngo, Minh Dao, Bartlett, Stacey, Bielefeldt-Ohmann, Helle, Foo, Cheng Xiang, Sinha, Roma, Arachchige, Buddhika Jayakody, Reed, Sarah, Mandrup-Poulsen, Thomas, Rosenkilde, Mette Marie, Ronacher, Katharina

“…Abstract Background We previously reported that reduced GPR183 expression in blood from tuberculosis (TB) patients with diabetes is associated with more severe…”
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EphA2 regulates vascular permeability and prostate cancer metastasis via modulation of cell junction protein phosphorylation by Offenhäuser, Carolin, Dave, Keyur A., Beckett, Kirrilee J., Smith, Fiona M., Jayakody, Buddhika A., Cooper, Leanne T., Agyei-Yeboah, Helen, McCarron, Jennifer K., Li, Yuchen, Bastick, Kate, Al-Ejeh, Fares, Cullen, Jason K., Coulthard, Mark G., Gorman, Jeffrey J., Boyd, Andrew W., Day, Bryan W.

“…Prostate cancer morbidity and mortality demonstrate a need for more effective targeted therapies. One potential target is EphA2, although paradoxically, pro-…”
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A primary human T-cell spectral library to facilitate large scale quantitative T-cell proteomics by Weerakoon, Harshi, Potriquet, Jeremy, Shah, Alok K., Reed, Sarah, Jayakody, Buddhika, Kapil, Charu, Midha, Mukul K., Moritz, Robert L., Lepletier, Ailin, Mulvenna, Jason, Miles, John J., Hill, Michelle M.

“…Data independent analysis (DIA) exemplified by sequential window acquisition of all theoretical mass spectra (SWATH-MS) provides robust quantitative proteomics…”
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Secreted and surface proteome and transcriptome of Opisthorchis felineus by Wong, Yide, Pearson, Mark S., Fedorova, Olga, Ivanov, Vladimir, Khmelevskaya, Ekaterina, Tedla, Bemnet, Arachchige, Buddhika Jayakody, Reed, Sarah, Field, Matt, Laha, Thewarach, Loukas, Alex, Sotillo, Javier

“…Introduction Opisthorchis felineus , Opisthorchis viverrini , and Clonorchis sinensis are the most medically important species of fish-borne zoonotic…”
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Proteoform-Specific Insights into Cellular Proteome Regulation by Norris, Emma L., Headlam, Madeleine J., Dave, Keyur A., Smith, David D., Bukreyev, Alexander, Singh, Toshna, Jayakody, Buddhika A., Chappell, Keith J., Collins, Peter L., Gorman, Jeffrey J.

“…Knowledge regarding compositions of proteomes at the proteoform level enhances insights into cellular phenotypes. A strategy is described herein for discovery…”
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Proteomic investigation of ALS motor cortex identifies known and novel pathogenetic mechanisms by Lee, Aven, Henderson, Robert, Arachchige, Buddhika Jayakody, Robertson, Thomas, McCombe, Pamela Ann

“…The key pathological feature in ALS is death of motor neurones from the brain and spinal cord, but the molecular mechanisms underlying this degeneration remain…”
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Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels by Lee, Aven, Arachchige, Buddhika Jayakody, Reed, Sarah, Henderson, Robert, Aylward, James, McCombe, Pamela Ann

“…The aim of this study was to determine whether patients with amyotrophic lateral sclerosis (ALS) exhibit higher plasma levels of formaldehyde (FA) than…”
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Elevated plasma levels of D-serine in some patients with amyotrophic lateral sclerosis by Lee, Aven, Arachchige, Buddhika Jayakody, Henderson, Robert, Pow, David, Reed, Sarah, Aylward, James, McCombe, Pamela Ann

“…D-serine is an endogenous co-agonist with glutamate for activation of the N-methyl-D-aspartate receptor (NMDAR). D-serine exacerbates neuronal death and is…”
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GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection by Foo, Cheng Xiang, Bartlett, Stacey, Chew, Keng Yih, Ngo, Minh Dao, Bielefeldt-Ohmann, Helle, Arachchige, Buddhika Jayakody, Matthews, Benjamin, Reed, Sarah, Wang, Ran, Smith, Christian, Sweet, Matthew J, Burr, Lucy, Bisht, Kavita, Shatunova, Svetlana, Sinclair, Jane E, Parry, Rhys, Yang, Yuanhao, Lévesque, Jean-Pierre, Khromykh, Alexander, Rosenkilde, Mette Marie, Short, Kirsty R, Ronacher, Katharina

“…Severe viral respiratory infections are often characterised by extensive myeloid cell infiltration and activation and persistent lung tissue injury. However,…”
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Abstract 2041: Quantitative phosphoproteomic analysis of EphA2 signaling in PC-3 prostate cancer cells by Offenhäuser, Carolin, Dave, Keyur A., Jayakody, Buddhika A., Gorman, Jeffrey J., Boyd, Andrew W.

“…Abstract The receptor tyrosine kinase EphA2 is frequently upregulated in cancer, where it plays an intriguing dichotomous role that may lend itself to…”
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