Search Results - "Jawalekar, Snehal"
-
1
Human arginase 1, a Jack of all trades?
Published in 3 Biotech (01-10-2022)“…Arginine, a conditionally essential amino acid, plays a crucial role in several metabolic and signalling pathways. Arginine metabolism in the body can be…”
Get full text
Journal Article -
2
Is highly expressed ACE 2 in pregnant women “a curse” in times of COVID-19 pandemic?
Published in Life sciences (1973) (01-01-2021)“…Angiotensin-converting enzyme 2 (ACE 2) is a membrane-bound enzyme that cleaves angiotensin II (Ang II) into angiotensin (1–7). It also serves as an important…”
Get full text
Journal Article -
3
Broad-spectrum anti-cancer activity of fused human arginase variants
Published in Investigational new drugs (20-08-2024)“…The rapid increase in cancer cases worldwide necessitates the development of novel therapeutic approaches. Therapies targeting cancer's altered metabolism,…”
Get full text
Journal Article -
4
Methionine as a double-edged sword in health and disease: Current perspective and future challenges
Published in Ageing research reviews (01-12-2021)“…Methionine is one of the essential amino acids and plays a vital role in various cellular processes. Reports advocate that methionine restriction and…”
Get full text
Journal Article -
5
Protein Chimerization: A New Frontier for Engineering Protein Therapeutics with Improved Pharmacokinetics
Published in The Journal of pharmacology and experimental therapeutics (01-09-2019)“…With the advancement of medicine, the utility of protein therapeutics is increasing exponentially. However, a significant number of protein therapeutics suffer…”
Get more information
Journal Article -
6
Development and characterization of fused human arginase I for cancer therapy
Published in Investigational new drugs (01-10-2023)“…Recombinant human arginase I (rhArg I) have emerged as a potential candidate for the treatment of varied pathophysiological conditions ranging from…”
Get full text
Journal Article