Search Results - "Jawahar, G."

Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research data by Wright, Caroline F, Dr, Fitzgerald, Tomas W, MS, Jones, Wendy D, MBBS, Clayton, Stephen, MRes, McRae, Jeremy F, PhD, van Kogelenberg, Margriet, PhD, King, Daniel A, MD, Ambridge, Kirsty, BSc, Barrett, Daniel M, BSc, Bayzetinova, Tanya, BSc, Bevan, A Paul, PhD, Bragin, Eugene, MSc, Chatzimichali, Eleni A, PhD, Gribble, Susan, PhD, Jones, Philip, MSc, Krishnappa, Netravathi, MSc, Mason, Laura E, BSc, Miller, Ray, PhD, Morley, Katherine I, PhD, Parthiban, Vijaya, PhD, Prigmore, Elena, PhD, Rajan, Diana, MSc, Sifrim, Alejandro, PhD, Swaminathan, G Jawahar, PhD, Tivey, Adrian R, MSc, Middleton, Anna, PhD, Parker, Michael, Prof, Carter, Nigel P, PhD, Barrett, Jeffrey C, PhD, Hurles, Matthew E, PhD, FitzPatrick, David R, Prof, Firth, Helen V, DM

“…Summary Background Human genome sequencing has transformed our understanding of genomic variation and its relevance to health and disease, and is now starting…”
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Light-cardiogram, a simple technique for heart rate determination in adult zebrafish, Danio rerio by Mousavi, Seyed Ehsan, Patil, Jawahar G.

“…Current techniques for heart rate determination in adult zebrafish require specialist expertise and are often invasive, technically challenging and not readily…”
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DECIPHER: database for the interpretation of phenotype-linked plausibly pathogenic sequence and copy-number variation by Bragin, Eugene, Chatzimichali, Eleni A, Wright, Caroline F, Hurles, Matthew E, Firth, Helen V, Bevan, A Paul, Swaminathan, G Jawahar

“…The DECIPHER database (https://decipher.sanger.ac.uk/) is an accessible online repository of genetic variation with associated phenotypes that facilitates the…”
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Paternal source of germ plasm determinants in the viviparous teleost, Gambusia holbrooki; dads do matter by Razmi, Komeil, Mousavi, Seyed Ehsan, Patil, Jawahar G.

“…The identity of germ cells, the progenitors of life, is thought to be acquired by two modes; either by maternal signals (preformed) or induced de novo from…”
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Sex biased expression of anti-Mullerian hormone (amh) gene in a live bearing fish, Gambusia holbrooki: Evolutionary implications and potential role in sex differentiation by Kwan, Tzu Nin, Patil, Jawahar G.

“…The amh, a member of transforming growth factor-β (TGF-β) family, is known to play a critical role in vertebrate male sex differentiation, with its paralogue/s…”
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Stages of embryonic development in the live‐bearing fish, Gambusia holbrooki by Mousavi, Seyed Ehsan, Patil, Jawahar G.

“…Background Divergent morphology and placentation of Poeciliids make them suitable model for investigating how evolutionary selection has altered and conserved…”
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Comparative gonad histology and semen quality of normal (XY) and neo‐males (XX) of Atlantic salmon (Salmo salar) by de Castro, Pedro Luiz, Patil, Jawahar G.

“…With an overarching objective of improving the hatchery production of Atlantic salmon (Salmo salar) all‐female progeny, this study comparatively evaluated the…”
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A novel testicular degenerative condition in a wild population of the common carp Cyprinus carpio (L) by Mahmud, Raihan, Purser, John, Patil, Jawahar G.

“…Gonad abnormalities can restrict or completely block reproductive capability of individuals and in some case that of their populations. Here, we describe a…”
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Daily ageing to delineate population dynamics of the invasive fish Gambusia holbrooki: implications for management and control by Nguyen, Hoang, Bell, Justin D., Patil, Jawahar G.

“…Despite the high global invasion profile of Gambusia holbrooki , there is limited knowledge of its population dynamics, especially biological parameters for…”
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Reproductive viability of paradoxically masculinised Gambusia holbrooki generated following diethylstilbestrol (DES) treatment by Patil, Jawahar.G., Norazmi-Lokman, Nor Hakim, Kwan, Tzu Nin

“…Hormonal sex reversal can produce monosex fish stocks and provide insights into their gamity and reproductive physiology. However, paradoxical effects have…”
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Gonad Ontogeny and Sex Differentiation in a Poeciliid, Gambusia holbrooki : Transition from a Bi- to a Mono-Lobed Organ by Razmi, Komeil, Tran, Ngoc Kim, Patil, Jawahar G

“…Despite their uniqueness, the ontogeny and differentiation of the single-lobed gonads in the poeciliids are very poorly understood. To address this, we…”
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Primordial Germ Cell Development in the Poeciliid, Gambusia holbrooki , Reveals Shared Features Between Lecithotrophs and Matrotrophs by Razmi, Komeil, Patil, Jawahar G

“…Metazoans exhibit two modes of primordial germ cell (PGC) specification that are interspersed across taxa. However, the evolutionary link between the two modes…”
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Genome-wide identification and expression profile analysis of nuclear factor Y family genes in Sorghum bicolor L. (Moench) by Maheshwari, P, Kummari, Divya, Palakolanu, Sudhakar Reddy, Nagasai Tejaswi, U, Nagaraju, M, Rajasheker, G, Jawahar, G, Jalaja, N, Rathnagiri, P, Kavi Kishor, P B

“…Members of the plant Heme Activator Protein (HAP) or NUCLEAR FACTOR Y (NF-Y) are trimeric transcription factor complexes composed of the NF-YA, NF-YB and NF-YC…”
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Enhanced mitotic arrest and chromosome resolution for cytogenetic analysis in the eastern mosquitofish, Gambusia holbrooki by Mousavi, Seyed Ehsan, Grützner, Frank, Patil, Jawahar G.

“…Maximising the number of cells arrested at metaphase and their resolution is fundamentally important for molecular cytogenetic investigations, particularly in…”
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Sex steroids have opposing effects on heart rate of juveniles, Gambusia holbrooki by Mousavi, Seyed Ehsan, Razmi, Komeil, Patil, Jawahar G

“…Graphical abstract Abstract Built on our recent work that heart rates (HRs) and function in Gambusia holbrooki are sexually dimorphic, this study assessed…”
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Gravid Spot Predicts Developmental Progress and Reproductive Output in a Livebearing Fish, Gambusia holbrooki by Norazmi-Lokman, Nor Hakim, Purser, G J, Patil, Jawahar G

“…In most livebearing fish, the gravid spot is an excellent marker to identify brooding females, however its use to predict progress of embryonic development,…”
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Masculinization of Adult Gambusia holbrooki : A Case of Recapitulation of Protogyny in a Gonochorist? by Tran, Ngoc Kim, Kwan, Tzu Nin, Purser, John, Patil, Jawahar G

“…17α-Methyltestosterone (MT) is a synthetic steroid that has been widely used to masculinize many fish species when administered early during larval…”
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Rare Variants in NR2F2 Cause Congenital Heart Defects in Humans by Al Turki, Saeed, Manickaraj, Ashok K., Mercer, Catherine L., Gerety, Sebastian S., Hitz, Marc-Phillip, Lindsay, Sarah, D’Alessandro, Lisa C.A., Swaminathan, G. Jawahar, Bentham, Jamie, Arndt, Anne-Karin, Louw, Jacoba, Breckpot, Jeroen, Gewillig, Marc, Thienpont, Bernard, Abdul-Khaliq, Hashim, Harnack, Christine, Hoff, Kirstin, Kramer, Hans-Heiner, Schubert, Stephan, Siebert, Reiner, Toka, Okan, Cosgrove, Catherine, Watkins, Hugh, Lucassen, Anneke M., O’Kelly, Ita M., Salmon, Anthony P., Bu’Lock, Frances A., Granados-Riveron, Javier, Setchfield, Kerry, Thornborough, Chris, Brook, J. David, Mulder, Barbara, Klaassen, Sabine, Bhattacharya, Shoumo, Devriendt, Koen, FitzPatrick, David R., Wilson, David I., Mital, Seema, Hurles, Matthew E.

“…Congenital heart defects (CHDs) are the most common birth defect worldwide and are a leading cause of neonatal mortality. Nonsyndromic atrioventricular septal…”
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Biomarker-assisted assessment of aquatic health using the cosmopolitan common carp, Cyprinus carpio (L): a case study of bisphenol-A exposures by Holeyappa, Shanthanagouda Admane, Kaur, Amandeep, Bansal, Neelam, Ansal, Meera D., Patil, Jawahar G., Thammegowda, Naveenkumar Billekallu, Kaur, Vaneet Inder, Sethi, Ram Saran

“…Monitoring aquatic health from environmental pollutants is critical, none more so than bisphenol-A (BPA), a ubiquitous endocrine-disrupting chemical (EDC). The…”
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Eradication of the Invasive Common Carp, Cyprinus carpio from a Large Lake: Lessons and Insights from the Tasmanian Experience by Yick, Jonah L., Wisniewski, Chris, Diggle, John, Patil, Jawahar G.

“…Common carp (Cyprinus carpio, L. 1758) are the most abundant pest fish species in Australia, detrimental to ecosystem integrity and values, and in need of…”
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