Search Results - "Javela, Kaija"

Significance of quantitative measurement of heparin-induced platelet antibodies by Javela, Kaija, Kekomäki, Riitta, Koskinen, Sinikka

“…Background:  Heparin‐induced thrombocytopenia (HIT) is a prothrombotic immune‐mediated adverse drug reaction. Antigen and platelet activation assays are used…”
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Soluble glycoprotein V as a quality marker of platelet concentrates stressed by transportation by Javela, Kaija, Eronen, Juha, Sarna, Seppo, Kekomäki, Riitta

“…BACKGROUND: Despite ongoing improvements in storage conditions for platelet concentrates (PCs) for clinical use, leukoreduced platelets (PLTs) undergo subtle…”
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Maternal HLA genotyping is not useful for predicting severity of fetal and neonatal alloimmune thrombocytopenia by Sainio, Susanna, Javela, Kaija, Tuimala, Jarno, Haimila, Katri

“…Summary Lack of reliable laboratory parameters is the main challenge in the management of fetal and neonatal alloimmune thrombocytopenia (FNAIT). Despite the…”
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Altered platelet shape change in hereditary gelsolin Asp187Asn-related amyloidosis by Kiuru, S, Javela, K, Somer, H, Kekomäki, R

“…Hereditary gelsolin-related amyloidosis (AGel amyloidosis) is a systemic disorder caused by a G654A or G654T mutation in the gene coding for gelsolin, an…”
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Autoimmune heparin‐induced thrombocytopenia of delayed onset: a clinical challenge by Kuitunen, Anne, Sinisalo, Marjatta, Vahtera, Annukka, Hiltunen, Leena, Javela, Kaija, Laine, Outi

“…BACKGROUND Heparin‐induced thrombocytopenia (HIT) usually appears at 5 to 10 days after initiation of heparin. Autoimmune HIT can arise after discontinuation…”
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Great discrepancy in antithrombin activity measured using five commercially available functional assays by Javela, Kaija, Engelbarth, Sari, Hiltunen, Leena, Mustonen, Pirjo, Puurunen, Marja

“…Abstract Introduction Congenital antithrombin (AT) deficiency is an inherited thrombophilia with high thrombosis prevalence. It has been reported that…”
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Variant Bernard-Soulier syndrome due to homozygous Asn45Ser mutation in the platelet glycoprotein (GP) IX in seven patients of five unrelated Finnish families by Koskela, Satu, Javela, Kaija, Jouppila, Jussi, Juvonen, Eeva, Nyblom, Olle, Partanen, Jukka, Kekomäki, Riitta

“…:  Bernard‐Soulier syndrome (BSS), a rare bleeding disorder with macrothrombocytopenia, is caused by a defect of the platelet glycoprotein (GP) Ib/IX/V…”
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Assessment of Time-Dependent Platelet Activation Using Extracellular Vesicles, CD62P Exposure, and Soluble Glycoprotein V Content of Platelet Concentrates with Two Different Platelet Additive Solutions by Valkonen, Sami, Mallas, Birte, Impola, Ulla, Valkeajärvi, Anne, Eronen, Juha, Javela, Kaija, Siljander, Pia R.-M., Laitinen, Saara

“…Novel analytical measures are needed to accurately monitor the properties of platelet concentrates (PCs). Since activated platelets produce platelet-derived…”
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Fetal intracranial haemorrhages caused by fetal and neonatal alloimmune thrombocytopenia: an observational cohort study of 43 cases from an international multicentre registry by Tiller, Heidi, Kamphuis, Marije M, Flodmark, Olof, Papadogiannakis, Nikos, David, Anna L, Sainio, Susanna, Koskinen, Sinikka, Javela, Kaija, Wikman, Agneta Taune, Kekomaki, Riitta, Kanhai, Humphrey H H, Oepkes, Dick, Husebekk, Anne, Westgren, Magnus

“…Objective To characterise pregnancies where the fetus or neonate was diagnosed with fetal and neonatal alloimmune thrombocytopenia (FNAIT) and suffered from…”
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Seasonal variation in high density lipoprotein cholesterol by Mänttäri, M, Javela, K, Koskinen, P, Pikkarainen, J, Manninen, V, Huttunen, J K, Frick, M H

“…We investigated the seasonal variation in high density lipoprotein cholesterol (HDL) in 142 dyslipidemic (non-HDL-cholesterol > or = 5.2 mmol/l) middle-aged…”
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Alloantibodies against low-frequency human platelet antigens do not account for a significant proportion of cases of fetomaternal alloimmune thrombocytopenia: evidence from 1054 cases by Ghevaert, Cedric, Rankin, Angela, Huiskes, Elly, Porcelijn, Leendert, Javela, Kaija, Kekomaki, Riitta, Bakchoul, Tamam, Santoso, Sentot, Nutland, Sarah, Smyth, Deborah J., Smith, Graham A., McBride, Simon, Watkins, Nicholas A., Ouwehand, Willem H.

“…BACKGROUND: Maternal alloantibodies against the five common human platelet antigen (HPA) systems (HPA‐1 to ‐3, ‐5, and ‐15) are found in only 20% of cases…”
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Thrombopoietin levels in cord blood plasma and amniotic fluid in fetuses with alloimmune thrombocytopenia and healthy controls by Sainio, Susanna, Javela, Kaija, Kekomäki, Riitta, Teramo, Kari

“…To extend our knowledge of the kinetics of fetal thrombopoietin (TPO), we studied TPO levels in cord blood plasma and amniotic fluid collected from 15 fetuses…”
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Evaluation of stored platelets

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Genetic polymorphism H131R of Fcγ receptor type IIA (FcγRIIA) in a healthy Finnish population and in patients with or without platelet-associated IgG by Joutsi, Lotta, Javela, Kaija, Partanen, Jukka, Kekomäki, Riitta

“…: Patients (n = 113) with histories of thrombocytopenia and with different profiles for platelet‐associated IgG (PA‐IgG) were subdivided according to the…”
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Detection of reticulated platelets: estimating the degree of fluorescence of platelets stained with thiazole orange by Joutsi-Korhonen, Lotta, Sainio, Susanna, Riikonen, Seija, Javela, Kaija, Teramo, Kari, Kekomäki, Riitta

“…: The primary problem in the measurement of reticulated platelets (RP) stained with thiazole orange (TO) by flow cytometry is the definition of a threshold…”
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Prevalence of diabetes mellitus and impaired glucose tolerance in the middle-aged population of three areas in Finland by Tuomilehto, J, Korhonen, H J, Kartovaara, L, Salomaa, V, Stengård, J H, Pitkänen, M, Aro, A, Javela, K, Uusitupa, M, Pitkäniemi, J

“…The prevalence of diabetes mellitus and impaired glucose tolerance (IGT) was determined in a random sample of the population aged 45-64 years in three areas of…”
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