Search Results - "Javaran, Mokhtar Jalali"
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Reteplase Fc-fusions produced in N. benthamiana are able to dissolve blood clots ex vivo
Published in PloS one (30-11-2021)“…Thrombolytic and fibrinolytic therapies are effective treatments to dissolve blood clots in stroke therapy. Thrombolytic drugs activate plasminogen to its…”
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Bottleneck removal of paclitaxel biosynthetic pathway by overexpression of DBTNBT gene under methyl-β-cyclodextrin and coronatine elicitation in Taxus baccata L
Published in Plant cell, tissue and organ culture (01-05-2022)“…Paclitaxel is a highly functionalized diterpenoid that is broadly used for the treatment of several cancer types. This valuable specialized metabolite…”
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How Different Genetically Manipulated Brassica Genotypes Affect Life Table Parameters of Plutella xylostella (Lepidoptera: Plutellidae)
Published in Journal of economic entomology (01-04-2015)“…The fitness of Plutella xylostella L. on different genetically manipulated Brassica plants, including canola's progenitor (Brassica rapa L.), two cultivated…”
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Quantitative Genetic Analysis Reveals Potential to Genetically Improve Fruit Yield and Drought Resistance Simultaneously in Coriander
Published in Frontiers in plant science (20-04-2017)“…Enhancing water use efficiency of coriander ( L.) is a major focus for coriander breeding to cope with drought stress. The purpose of this study was; (a) to…”
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Endoplasmic reticulum retention signaling and transmembrane channel proteins predicted for oilseed ω3 fatty acid desaturase 3 (FAD3) genes
Published in Functional & integrative genomics (01-05-2020)“…Oilseed crop oils contain a variety of unsaturated fatty acids that are synthesized and regulated by fatty acid desaturases (FADs). In this study, 14 FAD3 (ω3…”
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Investigation of the new substitution glycine to alanine within the Kringle-2 domain of reteplase: a molecular dynamics study
Published in Biotechnologia (Poznan) (2024)“…Recombinant plasminogen activator (r-PA) consists of the Kringle-2 and protease domains of human tissue-type plasminogen. It is used clinically to treat…”
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Enhanced expression and purification of anti-VEGF nanobody in cucurbit plants
Published in Journal of plant biochemistry and biotechnology (01-09-2019)“…Neutralizing nanobodies against vascular endothelial growth factor (VEGF) and its receptors are the most important types of medicine which are used in cancer…”
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The Effect of Methyl Jasmonate and Temperature on the Transient Expression of Recombinant Proteins in Cucurbita pepo L
Published in Molecular biotechnology (01-02-2019)“…The aim of this study is to assess the effect of methyl jasmonate (MeJA) and temperature on the valuable pharmaceuticals expression in a virus-mediated…”
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An investigation of the HMGR gene and IPI gene expression in black caraway (Bunium persicum)
Published in 3 Biotech (01-09-2018)“…Black caraway is of great importance for its terpene compounds. Many genes are involved in the biosynthesis of secondary metabolites in medicinal plants. For…”
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Effects of acclimation and diapause on the thermal tolerance of the two-spotted spider mite Tetranychus urticae
Published in Journal of thermal biology (01-10-2012)“…The two-spotted spider mite, Tetranychus urticae, is a worldwide pest species that overwinters as diapausing females. Cold hardening is presumed to start…”
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Apoplastic Production of Recombinant AntiVEGF Protein Using Plant-Virus Transient Expression Vector
Published in Molecular biotechnology (01-09-2022)“…Targeting of vascular endothelial growth factor (VEGF) using AntiVEGF can be a promising approach for angiogenesis inhibition and cancer therapy. In this…”
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Production and characterization of anti-(mucin MUC1) single-domain antibody in tobacco (Nicotiana tabacum cultivar Xanthi)
Published in Biotechnology and applied biochemistry (01-05-2007)“…Members of the Camelidae (camels, dromedaries, llamas, alpacas, guanacos and vicunas) are known to produce Igs (immunoglobulins) devoid of light chains and…”
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Fruit yield, fatty and essential oils content genetics in coriander
Published in Industrial crops and products (30-12-2016)“…•GCA×water treatment (WT) and SCA×WT interactions were significant (P≤0.01).•Essential oil content (EOC) controlled by dominance gene action in water…”
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Fusion to elastin-like polypeptide increases production of bioactive human IFN-γ in tobacco
Published in Transgenic research (01-08-2020)“…The plant-based expression systems are now accredited as bioreactors for the high production of various biopharmaceuticals. However, low levels of…”
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Identification of rate-limiting enzymes involved in paclitaxel biosynthesis pathway affected by coronatine and methyl-β-cyclodextrin in Taxus baccata L. cell suspension cultures
Published in Daru (01-12-2018)“…Background Paclitaxel is a potent antitumor alkaloid widely used for the treatment of several cancer types. This valuable secondary metabolite naturally exists…”
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Purification of recombinant tissue plasminogen activator (rtPA) protein from transplastomic tobacco plants
Published in Plant physiology and biochemistry (01-11-2016)“…Plants are low cost platforms for the production of recombinant proteins, but their complexity renders the purification of plant recombinant proteins more…”
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Dicistronic expression of human proinsulin-protein A fusion in tobacco chloroplast
Published in Biotechnology and applied biochemistry (01-01-2015)“…Different expression systems such as bacteria and mammalian cells have been used to produce pharmaceutical proteins. In recent years, the use of plants as…”
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Expression and Large-Scale Production of Human Tissue Plasminogen Activator (t-PA) in Transgenic Tobacco Plants Using Different Signal Peptides
Published in Applied biochemistry and biotechnology (01-03-2013)“…An attempt was made to assess the expression level and targeting of a human protein entitled recombinant tissue plasminogen activator (rt-PA) through…”
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Transient expression of anti-VEFGR2 nanobody in Nicotiana tabacum and N. benthamiana
Published in 3 Biotech (01-12-2018)“…In human, the interaction between vascular endothelial growth factor (VEGF) and its receptor (VEGFR2) is critical for tumor angiogenesis. This is a vital…”
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