Search Results - "Javaid, Muhammad K"

Central Sensitization in Knee Osteoarthritis: Relating Presurgical Brainstem Neuroimaging and PainDETECT‐Based Patient Stratification to Arthroplasty Outcome by Soni, Anushka, Wanigasekera, Vishvarani, Mezue, Melvin, Cooper, Cyrus, Javaid, Muhammad K., Price, Andrew J., Tracey, Irene

“…Objective The neural mechanisms of pain in knee osteoarthritis (OA) are not fully understood, and some patients have neuropathic‐like pain associated with…”
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Glucocorticoids induce specific ion-channel-mediated toxicity in human rotator cuff tendon: a mechanism underpinning the ultimately deleterious effect of steroid injection in tendinopathy? by Dean, Benjamin John Floyd, Franklin, Sarah Louise, Murphy, Richard J, Javaid, Muhammad K, Carr, Andrew Jonathan

“…Glucocorticoid injection (GCI) and surgical rotator cuff repair are two widely used treatments for rotator cuff tendinopathy. Little is known about the way in…”
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Longitudinal dynamics and clinically available predictors of poor response to COVID-19 vaccination in multiple myeloma by Agarwal, Gaurav, Moore, Sally, Sadler, Ross, Varghese, Sherin, Turner, Alison, Chen, Lucia Y, Larham, Jemma, Gray, Nathanael, Carty, Oluremi, Barrett, Joe, Koshiaris, Constantinos, Kothari, Jaimal, Bowcock, Stella, Oppermann, Udo, Gamble, Vicky, Cook, Gordon, Kyriakou, Chara, Drayson, Mark, Basu, Supratik, McDonald, Sarah, McKinley, Shelagh, Gooding, Sarah, Javaid, Muhammad K, Ramasamy, Karthik

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Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta by Hald, Jannie D, Keerie, Catriona, Weir, Christopher J, Javaid, Muhammad K, Lam, Wayne, Osborne, Patricia, Walsh, Jennifer, Langdahl, Bente L, Ralston, Stuart H

“…IntroductionOsteogenesis imperfecta (OI) is a rare genetic disease associated with multiple fractures throughout life. It is often treated with osteoporosis…”
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Patients' recovery of mobility and return to original residence after hip fracture are associated with multiple modifiable components of hospital service organisation: the REDUCE record-linkage cohort study in England and Wales by Patel, Rita, Judge, Andrew, Johansen, Antony, Marques, Elsa M R, Chesser, Tim, Griffin, Xavier L, Javaid, Muhammad K, Ben-Shlomo, Yoav, Gregson, Celia L

“…Hip fractures are devastating injuries causing disability, dependence, and institutionalisation, yet hospital care is highly variable. This study aimed to…”
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Increased development of radiographic hip osteoarthritis in individuals with high bone mass: a prospective cohort study by Hartley, April, Hardcastle, Sarah A, Frysz, Monika, Parkinson, Jon, Paternoster, Lavinia, McCloskey, Eugene, Poole, Kenneth E S, Javaid, Muhammad K, Aye, Mo, Moss, Katie, Williams, Martin, Tobias, Jon H, Gregson, Celia L

“…Individuals with high bone mass (HBM) have a greater odds of prevalent radiographic hip osteoarthritis (OA), reflecting an association with bone-forming OA…”
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Exercise or manual physiotherapy compared with a single session of physiotherapy for osteoporotic vertebral fracture: three-arm PROVE RCT by Barker, Karen L, Newman, Meredith, Stallard, Nigel, Leal, Jose, Minns Lowe, Catherine, Javaid, Muhammad K, Noufaily, Angela, Adhikari, Anish, Hughes, Tamsin, Smith, David J, Gandhi, Varsha, Cooper, Cyrus, Lamb, Sarah E

“…A total of 25,000 people in the UK have osteoporotic vertebral fracture (OVF). Evidence suggests that physiotherapy may have an important treatment role. The…”
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Assessing a 12-month course of oral alendronate for adults with avascular necrosis of the hip: MANTIS RCT with internal pilot by Glyn-Jones, Sion, Javaid, Muhammad K, Beard, David, Newton, Julia, Kerslake, Robert, McBryde, Callum, Board, Tim, Dutton, Susan J, Dritsaki, Melina, Khanduja, Vikas, Akanni, Magbor, Sexton, Shaun, Skinner, John, Peckham, Nicholas, Knight, Ruth, Rombach, Ines, Davies, Loretta, Barber, Vicki

“…People with avascular necrosis of the hip have very limited treatment options currently available to stop the progression of this disease; this often results…”
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REducing unwarranted variation in the Delivery of high qUality hip fraCture services in England and Wales (REDUCE): protocol for a mixed-methods study by Patel, Rita, Drew, Sarah, Johansen, Antony, Chesser, Tim, Javaid, Muhammad K, Griffin, Xavier L, Jones, Tim, Griffin, Jill, Bradshaw, Marianne, Whale, Katie, Barbosa, Estela Capelas, Marques, Elsa M R, Ben-Shlomo, Yoav, Gooberman-Hill, Rachael, Judge, Andrew, Gregson, Celia L

“…IntroductionSubstantial variation in the delivery of hip fracture care, and patient outcomes persists between hospitals, despite established UK national…”
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Benefit of burosumab in adults with X-linked hypophosphataemia (XLH) is maintained with long-term treatment by Kamenicky, Peter, Briot, Karine, Brandi, Maria Luisa, Cohen-Solal, Martine, Crowley, Rachel K, Keen, Richard, Kolta, Sami, Lachmann, Robin H, Lecoq, Anne-Lise, Ralston, Stuart H, Walsh, Jennifer S, Rylands, Angela J, Williams, Angela, Sun, Wei, Nixon, Annabel, Nixon, Mark, Javaid, Muhammad K

“…ObjectivesTo report the impact of continued burosumab treatment on clinical laboratory tests of efficacy, patient-reported outcomes (PROs) and ambulatory…”
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Inflammatory bowel disease and the risk of fracture by Van staa, Tjeerd-Pieter, Cooper, Cyrus, Samuels Brusse, Listy, Leufkens, Hubert, Javaid, Muhammad K, Arden, Nigel K

“…Background & Aims: Although patients with inflammatory bowel disease (IBD) have reduced bone mass, there is controversy whether there is an increased risk of…”
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CYP3A4 mutation causes vitamin D-dependent rickets type 3 by Roizen, Jeffrey D, Li, Dong, O'Lear, Lauren, Javaid, Muhammad K, Shaw, Nicholas J, Ebeling, Peter R, Nguyen, Hanh H, Rodda, Christine P, Thummel, Kenneth E, Thacher, Tom D, Hakonarson, Hakon, Levine, Michael A

“…Genetic forms of vitamin D-dependent rickets (VDDRs) are due to mutations impairing activation of vitamin D or decreasing vitamin D receptor responsiveness…”
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COVID symptoms, testing, shielding impact on patient‐reported outcomes and early vaccine responses in individuals with multiple myeloma by Ramasamy, Karthik, Sadler, Ross, Jeans, Sally, Varghese, Sherin, Turner, Alison, Larham, Jemma, Gray, Nathanael, Barrett, Joe, Bowcock, Stella, Cook, Gordon, Kyriakou, Chara, Smith, Dean, Drayson, Mark, Basu, Supratik, Moore, Sally, McDonald, Sarah, Gooding, Sarah, Javaid, Muhammad K.

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Immune response to COVID‐19 vaccination is attenuated by poor disease control and antimyeloma therapy with vaccine driven divergent T‐cell response by Ramasamy, Karthik, Sadler, Ross, Jeans, Sally, Weeden, Paul, Varghese, Sherin, Turner, Alison, Larham, Jemma, Gray, Nathanael, Carty, Oluremi, Barrett, Joe, Bowcock, Stella, Oppermann, Udo, Cook, Gordon, Kyriakou, Chara, Drayson, Mark, Basu, Supratik, Moore, Sally, McDonald, Sarah, Gooding, Sarah, Javaid, Muhammad K.

“…Summary Myeloma patients frequently respond poorly to bacterial and viral vaccination. A few studies have reported poor humoral immune responses in myeloma…”
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Following hip fracture, hospital organizational factors associated with prescription of anti-osteoporosis medication on discharge, to address imminent refracture risk: a record-linkage study by Patel, Rita, Judge, Andrew, Johansen, Antony, Javaid, Muhammad K, Griffin, Xavier L, Chesser, Tim, Griffin, Jill, Marques, Elsa M R, Ben-Shlomo, Yoav, Gregson, Celia L

“…Patients who sustain a hip fracture are known to be at imminent refracture risk. Their complex multidisciplinary rehabilitation needs to include falls…”
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An Expert Perspective on Phosphate Dysregulation With a Focus on Chronic Hypophosphatemia by Aljuraibah, Fahad, Bacchetta, Justine, Brandi, Maria Luisa, Florenzano, Pablo, Javaid, Muhammad K, Mäkitie, Outimaija, Raimann, Adalbert, Rodriguez, Mariano, Siggelkow, Heide, Tiosano, Dov, Vervloet, Marc, Wagner, Carsten A

“…ABSTRACT Because of their rarity, diseases characterized by chronic hypophosphatemia can be underrecognized and suboptimally managed, resulting in poor…”
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Multiple hospital organisational factors are associated with adverse patient outcomes post-hip fracture in England and Wales: the REDUCE record-linkage cohort study by Patel, Rita, Judge, Andrew, Johansen, Antony, Marques, Elsa M R, Griffin, Jill, Bradshaw, Marianne, Drew, Sarah, Whale, Katie, Chesser, Tim, Griffin, Xavier L, Javaid, Muhammad K, Ben-Shlomo, Yoav, Gregson, Celia L

“…Abstract Objectives Despite established standards and guidelines, substantial variation remains in the delivery of hip fracture care across the United Kingdom…”
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Setrusumab for the treatment of osteogenesis imperfecta: 12-month results from the phase 2b asteroid study by Glorieux, Francis H, Langdahl, Bente, Chapurlat, Roland, De Beur, Suzanne Jan, Sutton, Vernon Reid, Poole, Kenneth E S, Dahir, Kathryn M, Orwoll, Eric S, Willie, Bettina M, Mikolajewicz, Nicholas, Zimmermann, Elizabeth, Hosseinitabatabaei, Seyedmahdi, Ominsky, Michael S, Saville, Chris, Clancy, James, MacKinnon, Alastair, Mistry, Arun, Javaid, Muhammad K

“…Osteogenesis imperfecta (OI) is a rare genetic disorder commonly caused by variants of the type I collagen genes COL1A1 and COL1A2. OI is associated with…”
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Health-related quality of life and a cost-utility simulation of adults in the UK with osteogenesis imperfecta, X-linked hypophosphatemia and fibrous dysplasia by Forestier-Zhang, Lydia, Watts, Laura, Turner, Alison, Teare, Harriet, Kaye, Jane, Barrett, Joe, Cooper, Cyrus, Eastell, Richard, Wordsworth, Paul, Javaid, Muhammad K, Pinedo-Villanueva, Rafael

“…Health-related quality of life of adults with osteogenesis imperfecta (OI), fibrous dysplasia (FD) and X-linked hypophosphatemia (XLH) remains poorly…”
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GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates by Roca-Ayats, Neus, Balcells, Susana, Garcia-Giralt, Natàlia, Falcó-Mascaró, Maite, Martínez-Gil, Núria, Abril, Josep F, Urreizti, Roser, Dopazo, Joaquín, Quesada-Gómez, José M, Nogués, Xavier, Mellibovsky, Leonardo, Prieto-Alhambra, Daniel, Dunford, James E, Javaid, Muhammad K, Russell, R. Graham, Grinberg, Daniel, Díez-Pérez, Adolfo

“…This letter describes the detection of GGPS1 and other mutations in three sisters who had atypical femoral fractures associated with long-term bisphosphonate…”
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