Search Results - "Javadi, Gholamreza"
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In silico/In vivo analysis of high-risk papillomavirus L1 and L2 conserved sequences for development of cross-subtype prophylactic vaccine
Published in Scientific reports (23-10-2019)“…Human papillomavirus (HPV) is the most common sexually transmitted infection in the world and the main cause of cervical cancer. Nowadays, the virus-like…”
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A comprehensive in silico analysis for identification of therapeutic epitopes in HPV16, 18, 31 and 45 oncoproteins
Published in PloS one (24-10-2018)“…Human papillomaviruses (HPVs) are a group of circular double-stranded DNA viruses, showing severe tropism to mucosal tissues. A subset of HPVs, especially…”
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Molecular Docking Analysis of 120 Potential HPV Therapeutic Epitopes Using a New Analytical Method
Published in International journal of peptide research and therapeutics (01-12-2020)“…The accurate modelling and scoring of protein–peptide (Pr–Pe) complexes are determining factors in the drug discovery studies by molecular docking. However,…”
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Radioprotective Effects of Combined Melatonin and Famotidine Treatment on Radiation Induced Apoptosis in Peripheral Blood Leukocytes of Breast Cancer Patients and Normal Individuals
Published in Cell journal (Yakhteh) (01-10-2021)“…The aim of this study was to evaluate the effects of individual or combined use of two antioxidants, melatonin and famotidine on radiation induced apoptosis in…”
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Association of GRIA1 polymorphisms with ovarian response to human menopausal gonadotropin in Iranian women
Published in Clinical and experimental reproductive medicine (01-09-2020)“…Objective: Glutamate ionotropic receptor AMPA type subunit 1 (GRIA1) is a subunit of a ligand-gated ion channel that regulates the secretion of…”
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Correlation of HER2, MDM2, c-MYC, c-MET, and TP53 Copy Number Alterations in Circulating Tumor Cells with Tissue in Gastric Cancer Patients: A Pilot Study
Published in Iranian biomedical journal (2020)“…The analysis of the gene copy number alterations in tumor samples are increasingly used for diagnostic and prognostic purposes in patients with gastric cancer…”
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Association of Candidate Single Nucleotide Polymorphisms Related to Candidate Genes in Patients With Schizophrenia
Published in Basic and clinical neuroscience (01-09-2020)“…Introduction: Schizophrenia is a chronic heterogenic neurodevelopment disorder. Many genes interfere in the development of SCZ. All four genes, NrCAM, PRODH,…”
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Evaluation of Myc Gene Expression as a Preventive Marker for Increasing the Implantation Success in the Infertile Women
Published in International journal of preventive medicine (01-01-2020)“…There are numerous couples worldwide currently suffering from infertility. Several factors, including genetic abnormalities are involved in infertility. In…”
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Association of GRIA1 polymorphisms with ovarian response to human menopausal gonadotropin in Iranian women
Published in Clinical and experimental reproductive medicine (2020)“…Objective: Glutamate ionotropic receptor AMPA type subunit 1 (GRIA1) is a subunit of a ligand-gated ion channel that regulates the secretion of…”
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A new aspect on the correlation of ten SNPs in MIR and their target genes in dopaminergic pathways in schizophrenia
Published in Bulletin of the National Research Centre (04-03-2022)“…Background Schizophrenia (SCZ) is a severe mental disorder in which people interpret reality abnormally. Different studies indicated a complex polygenic…”
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Expression of COLLAGEN 1 and ELASTIN Genes in Mitral Valvular Interstitial Cells within Microfiber Reinforced Hydrogel
Published in Cell journal (Yakhteh) (01-10-2015)“…The incidence of heart valve disease is increasing worldwide and the number of heart valve replacements is expected to increase in the future. By mimicking the…”
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Surveying Mutation of FLT3 Genes in Children with Acute Leukemia
Published in Asian Pacific journal of cancer care (18-02-2017)“…Background and purpose: Mutation of FMS like tyrosine kinase (flt3) gene causes uncontrolled proliferation of leukemic cells and a bad prognosis. The present…”
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A novel multi-epitope peptide vaccine against cancer: An in silico approach
Published in Journal of theoretical biology (21-05-2014)“…Cancer immunotherapy has an outstanding position in cancer prevention and treatment. In this kind of therapy, the immune system is activated to eliminate…”
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Combination of human papillomaviruses L1 and L2 multiepitope constructs protects mice against tumor cells
Published in Fundamental & clinical pharmacology (01-12-2021)“…Different types of cancer including cervical (>90%), anal (~88%), vaginal (~40%), and penile (~40%) cancers are associated with human papillomaviruse (HPV)…”
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LNA Inhibitor in microRNA miR-23b as a Potential Anti-proliferative Option in Human Hepatocellular Carcinoma
Published in Journal of gastrointestinal cancer (01-03-2020)“…Purpose Dysregulation of microRNAs (miRNAs) has been shown to be involved in the pathogenesis and progression of many malignancies. Human hepatocellular…”
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Dysregulated Expression of Long Non-Coding RNA MINCR and EZH2 in Colorectal Cancer
Published in Iranian biomedical journal (01-01-2022)“…As critical regulators, lncRNAs have attracted attention from researchers for diagnostic, prognostic, and therapeutic purposes in human carcinogenesis via…”
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Evaluation of the impact of polyclonal infection and heteroresistance on treatment of tuberculosis patients
Published in Scientific reports (25-01-2017)“…Mixed strain infections of Mycobacterium tuberculosis make diagnosis, treatment, and control of tuberculosis (TB) more difficult. This study was aimed to…”
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Fiber-reinforced hydrogel scaffolds for heart valve tissue engineering
Published in Journal of biomaterials applications (01-09-2014)“…Heart valve-related disorders are among the major causes of death worldwide. Although prosthetic valves are widely used to treat this pathology, current…”
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Chemical cross-linking of chitosan/polyvinyl alcohol electrospun nanofibers
Published in Materiali in tehnologije (18-10-2016)Get full text
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Development of multiepitope therapeutic vaccines against the most prevalent high-risk human papillomaviruses
Published in Immunotherapy (01-05-2020)“…Our goal was the development of DNA- or peptide-based multiepitope vaccines targeting HPV E7, E6 and E5 oncoproteins in tumor mouse model. After designing the…”
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