Search Results - "Jauzac, Philippe"
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1
Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells
Published in Journal of experimental & clinical cancer research (07-06-2009)“…opioid and somatostatin receptors (SSTRs) that can assemble as heterodimer were individually reported to modulate malignant cell proliferation and to favour…”
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2
Zinc status and bone mineralisation in adolescent girls
Published in Journal of trace elements in medicine and biology (01-01-2004)“…The aim of the project was to assess the relationship between zinc status and bone mineralisation in pre-menarcheal adolescent girls. One hundred and…”
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3
Potential use of early alterations in μ and δ opioid receptors as a predictive index for delayed brain ischemic damage
Published in Neurobiology of disease (01-06-2003)“…We previously reported differential alterations of the μ, δ, and κ opioid receptors following permanent middle cerebral artery occlusion. The present work…”
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4
ßarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands
Published in Cellular signalling (01-03-2012)“…We have previously reported on the differential regulation of the human δ-opioid receptor (hDOR) by alkaloid (etorphine) and peptidic (DPDPE and deltorphin I)…”
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5
Reduction of cell proliferation and potentiation of Fas-induced apoptosis by the selective kappa-opioid receptor agonist U50 488 in the multiple myeloma LP-1 cells
Published in Journal of neuroimmunology (30-03-2010)“…Abstract As opioid receptors modulate proliferation and apoptosis of immune cells, we hypothesized that they could reduce malignant haematopoietic cells. After…”
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6
Different kinases desensitize the human δ-opioid receptor (hDOP-R) in the neuroblastoma cell line SK-N-BE upon peptidic and alkaloid agonists
Published in Cellular signalling (01-06-2008)“…In a previous work, we described a differential desensitization of the human δ-opioid receptor (hDOP-R) by etorphine (a non-selective and alkaloid agonist) and…”
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7
Differential sorting of human delta-opioid receptors after internalization by peptide and alkaloid agonists
Published in The Journal of biological chemistry (20-06-2003)“…Desensitization and internalization of G protein-coupled receptors observed after agonist activation are considered two important regulatory processes of…”
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8
βarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands
Published in Cellular signalling (09-11-2011)“…We have previously reported on the differential regulation of the human δ-opioid receptor (hDOR) by alkaloid (etorphine) and peptidic (DPDPE and deltorphin I)…”
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9
Long-term alterations in mu, delta and kappa opioidergic receptors following middle cerebral artery occlusion in mice
Published in Acta neuropathologica (01-11-2007)“…Alterations in the opioidergic system may play a role in the molecular mechanisms underlying neurochemical responses to cerebral ischaemia. The present study…”
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10
High-purity selection and maintenance of gene expression in human neuroblastoma cells stably over-expressing GFP fusion protein Application for opioid receptors desensitization studies
Published in Brain research (09-10-2006)“…Chronic use of opiates such as morphine is associated with drug tolerance, which is correlated with the desensitization of opioid receptors. This latter…”
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11
Long-term alterations in [mu], [delta] and [kappa] opioidergic receptors following middle cerebral artery occlusion in mice
Published in Acta neuropathologica (01-11-2007)“…Alterations in the opioidergic system may play a role in the molecular mechanisms underlying neurochemical responses to cerebral ischaemia. The present study…”
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12
High-purity selection and maintenance of gene expression in human neuroblastoma cells stably over-expressing GFP fusion protein
Published in Brain research (09-10-2006)“…Chronic use of opiates such as morphine is associated with drug tolerance, which is correlated with the desensitization of opioid receptors. This latter…”
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13
Pharmacological characterization of AR-M1000390 at human delta opioid receptors
Published in Life sciences (1973) (15-08-2003)“…We investigated the pharmacological properties of a newly synthesised δ agonist AR-M1000390, derived from SNC-80 ((+)-4-[(alpha…”
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14
Differential Sorting of Human δ-Opioid Receptors after Internalization by Peptide and Alkaloid Agonists
Published in The Journal of biological chemistry (20-06-2003)“…Desensitization and internalization of G protein-coupled receptors observed after agonist activation are considered two important regulatory processes of…”
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15
Internalization and recycling of delta-opioid receptor are dependent on a phosphorylation-dephosphorylation mechanism
Published in The Journal of pharmacology and experimental therapeutics (01-04-2000)“…Internalization, recycling, and resensitization of the human delta-opioid receptor (hDOR) were studied in the neuroblastoma cell line SK-N-BE, endogenously…”
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16
Potential use of early alterations in is a subset of and delta opioid receptors as a predictive index for delayed brain ischemic damage
Published in Neurobiology of disease (01-06-2003)“…We previously reported differential alterations of the is a subset of , delta , and mu opioid receptors following permanent middle cerebral artery occlusion…”
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17
Differential time-course decreases in nonselective, mu-, delta-, and kappa-opioid receptors after focal cerebral ischemia in mice
Published in Stroke (1970) (01-06-1999)“…Neuroprotection studies have demonstrated the involvement of opioids in ischemia, and we have previously demonstrated alterations in Bmax of opioidergic…”
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18
A novel mutation in the mitochondrial tRNA{sup Asn} gene associated with a lethal disease
Published in Biochemical and biophysical research communications (15-04-2005)“…We describe a lethal mitochondrial disease in a 10-month-old child who presented with encephalomyopathy. Histochemical and electron microscopy examinations of…”
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19
Desensitization of the δ‐Opioid Receptor Correlates with Its Phosphorylation in SK‐N‐BE Cells: Involvement of a G Protein‐Coupled Receptor Kinase
Published in Journal of neurochemistry (01-05-1998)“…: Phosphorylation of G protein‐coupled receptors is considered an important step during their desensitization. In SK‐N‐BE cells, recently presented as a…”
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20
Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE
Published in Biochemical journal (15-08-1999)“…Differences in the specificity of coupling of delta-opioid receptor with G-protein have been reported in the literature. We have observed a differential…”
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