Search Results - "Jasukaitiene, Aldona"
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Preoperative Immune Cell Dysregulation Accompanies Ovarian Cancer Patients into the Postoperative Period
Published in International journal of molecular sciences (28-06-2024)“…Ovarian cancer (OC) poses a significant global health challenge with high mortality rates, emphasizing the need for improved treatment strategies. The immune…”
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Targeting AHR Increases Pancreatic Cancer Cell Sensitivity to Gemcitabine through the ELAVL1-DCK Pathway
Published in International journal of molecular sciences (24-08-2023)“…The aryl hydrocarbon receptor (AHR) is a transcription factor that is commonly upregulated in pancreatic ductal adenocarcinoma (PDAC). AHR hinders the…”
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Assessing Adipocyte Viability and Surgeons’ Work Efficiency by Comparing Different Liposuction Methods
Published in Plastic and reconstructive surgery. Global open (01-08-2023)“…BackgroundAutologous fat grafting is widely used in plastic and reconstructive surgery. Liposuction methods play a key role in surgeons' work efficiency,…”
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HAMLET effect on cell death and mitochondrial respiration in colorectal cancer cell lines with KRAS/BRAF mutations
Published in Journal of cancer research and clinical oncology (01-09-2023)“…Purpose Treatment of advanced colorectal cancer (CRC) depends on the correct selection of personalized strategies. HAMLET (Human Alpha-lactalbumin Made LEthal…”
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Assessing the Therapeutic Impacts of HAMLET and FOLFOX on BRAF-Mutated Colorectal Cancer: A Study of Cancer Cell Survival and Mitochondrial Dynamics In Vitro and Ex Vivo
Published in Medicina (Kaunas, Lithuania) (01-01-2024)“…: Colorectal cancer (CRC) is a major global health challenge. The BRAF V600E mutation, found in 8-12% of CRC patients, exacerbates this by conferring poor…”
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Differentiating pancreatic cancer via cfDNA levels in liquid biopsies
Published in Journal of clinical oncology (01-06-2024)“…e16344 Background: Pancreatic cancer remains an aggressive and highly lethal disease, exhibiting an overall 5-year survival rate of merely 10%, among the…”
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Narrow line between benefit and harm: Additivity of hyperthermia to cisplatin cytotoxicity in different gastrointestinal cancer cells
Published in World journal of gastroenterology : WJG (14-03-2018)“…To investigate the response to hyperthermia and chemotherapy, analyzing apoptosis, cytotoxicity, and cisplatin concentration in different digestive system…”
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Different mitochondrial response to cisplatin and hyperthermia treatment in human AGS, Caco-2 and T3M4 cancer cell lines
Published in Journal of bioenergetics and biomembranes (01-10-2018)“…Gastrointestinal cancers (gastric, pancreatic and colorectal) are life-threatening diseases, which easily spread to peritoneal cavity (Juhl et al. in Int J…”
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Genetic variants of TCF7L2 gene and its coherence with metabolic parameters in Lithuanian (Kaunas district) women population with previously diagnosed gestational diabetes mellitus compared to general population
Published in Diabetes research and clinical practice (01-02-2021)“…To determine the association of genetic variants rs7901695, rs7903146, rs7895340, rs11196205, rs12255372 of transcription factor 7 like 2 (TCF7L2) gene and its…”
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Dysregulation of Peripheral Blood Mononuclear Cells and Immune-Related Proteins during the Early Post-Operative Immune Response in Ovarian Cancer Patients
Published in Cancers (30-12-2023)“…Surgical treatment is a cornerstone of ovarian cancer (OC) therapy and exerts a substantial influence on the immune system. Immune responses also play a…”
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Human antigen R mediated post-transcriptional regulation of inhibitors of apoptosis proteins in pancreatic cancer
Published in World journal of gastroenterology : WJG (14-01-2019)“…To determine the association of human antigen R (HuR) and inhibitors of apoptosis proteins (IAP1, IAP2) and prognosis in pancreatic cancer. Protein and mRNA…”
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Response of OVCAR-3 Cells to Cisplatin and Hyperthermia: Does Hyperthermia Really Matter?
Published in Anticancer research (01-09-2017)“…Hyperthermic intraperitoneal chemotherapy (HIPEC) is proposed as a promising treatment method, but fundamental information about the contribution of…”
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Association between AHR Expression and Immune Dysregulation in Pancreatic Ductal Adenocarcinoma: Insights from Comprehensive Immune Profiling of Peripheral Blood Mononuclear Cells
Published in Cancers (19-09-2023)“…Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), has an immune suppressive environment that allows tumour cells to evade the immune…”
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Association between IAHR/I Expression and Immune Dysregulation in Pancreatic Ductal Adenocarcinoma: Insights from Comprehensive Immune Profiling of Peripheral Blood Mononuclear Cells
Published in Cancers (01-09-2023)“…This study investigated the role of aryl hydrocarbon receptor (AHR) expression in pancreatic ductal adenocarcinoma patients’ peripheral blood immune cells…”
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Hyperthermia potentiates cisplatin cytotoxicity and negative effects on mitochondrial functions in OVCAR-3 cells
Published in Journal of bioenergetics and biomembranes (01-08-2019)“…The aim of this study was to determine the effects of hyperthermia, cisplatin and their combination on mitochondrial functions such as glutamate dehydrogenase…”
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Stimulated upregulation of HO-1 is associated with inadequate response of gastric and ovarian cancer cell lines to hyperthermia and cisplatin treatment
Published in Oncology letters (01-08-2019)“…Heme oxygenase (HO)-1 is a heat shock protein induced by hyperthermia, responsible for cellular resistance to temperature. The aim of this study was to clarify…”
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Suppression of heme oxygenase-1 protein as potential target in ovarian cancer treatment
Published in European journal of obstetrics & gynecology and reproductive biology (01-03-2019)Get full text
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Role of CUGBP2 and HUR Mediated Post-Transcriptional Regulation in Anti-Cancer Drugs Resistance of Pancreatic Adenocarcinoma
Published 01-01-2016“…Pancreatic ductal adenocarcinoma (PDAC) is aggressively invasive,treatment-resistant malignancy and usually detectable too late. The lethalityof pancreatic…”
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