Search Results - "Jaspard, Béatrice"

Decrease of Pdzrn3 is required for heart maturation and protects against heart failure by Pernot, Mathieu, Jaspard-vinassa, Béatrice, Abelanet, Alice, Rubin, Sebastien, Forfar, Isabelle, Jeanningros, Sylvie, Cetran, Laura, Yu, Murielle Han-Yee, Balse, Elise, Hatem, Stéphane, Dufourcq, Pascale, Couffinhal, Thierry, Duplàa, Cécile

“…Heart failure is the final common stage of most cardiopathies. Cardiomyocytes (CM) connect with others via their extremities by intercalated disk protein…”
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Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis by Mora, Pierre, Laisné, Margaux, Bourguignon, Célia, Rouault, Paul, Jaspard-Vinassa, Béatrice, Maître, Marlène, Gadeau, Alain-Pierre, Renault, Marie-Ange, Horng, Sam, Couffinhal, Thierry, Chapouly, Candice

“…Under neuroinflammatory conditions, astrocytes acquire a reactive phenotype that drives acute inflammatory injury as well as chronic neurodegeneration. We…”
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Sonic hedgehog mediates a novel pathway of PDGF-BB–dependent vessel maturation by Yao, Qinyu, Renault, Marie-Ange, Chapouly, Candice, Vandierdonck, Soizic, Belloc, Isabelle, Jaspard-Vinassa, Béatrice, Daniel-Lamazière, Jean-Marie, Laffargue, Muriel, Merched, Aksam, Desgranges, Claude, Gadeau, Alain-Pierre

“…Recruitment of mural cells (MCs), namely pericytes and smooth muscle cells (SMCs), is essential to improve the maturation of newly formed vessels. Sonic…”
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Therapies targeting Frizzled‐7/β‐catenin pathway prevent the development of pathological angiogenesis in an ischemic retinopathy model by Bats, Marie‐Lise, Bougaran, Pauline, Peghaire, Claire, Gueniot, Florian, Abelanet, Alice, Chan, Hélène, Séguy, Camille, Jeanningros, Sylvie, Jaspard‐Vinassa, Béatrice, Couffinhal, Thierry, Duplàa, Cécile, Dufourcq, Pascale

“…Retinopathies remain major causes of visual impairment in diabetic patients and premature infants. Introduction of anti‐angiogenic drugs targeting vascular…”
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Frizzled7 controls vascular permeability through the Wnt-canonical pathway and cross-talk with endothelial cell junction complexes by Ferreira Tojais, Nancy, Peghaire, Claire, Franzl, Nathalie, Larrieu-Lahargue, Frédéric, Jaspard, Béatrice, Reynaud, Annabelle, Moreau, Catherine, Couffinhal, Thierry, Duplàa, Cécile, Dufourcq, Pascale

“…Vascular permeability is essential for the health of normal tissues and is an important characteristic of many disease states. The role of the Wnt/frizzled…”
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uAUG creating variants in the 5’UTR of ENG causing Hereditary Hemorrhagic Telangiectasia by Soukarieh, Omar, Tillet, Emmanuelle, Proust, Carole, Dupont, Charlène, Jaspard-Vinassa, Béatrice, Soubrier, Florent, Goyenvalle, Aurélie, Eyries, Mélanie, Trégouët, David-Alexandre

“…Hereditary Hemorrhagic Telangiectasia (HHT) is a rare, autosomal dominant, vascular disorder. About 80% of cases are caused by pathogenic variants in ACVRL1…”
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Frizzled 4 Regulates Arterial Network Organization Through Noncanonical Wnt/Planar Cell Polarity Signaling by Descamps, Betty, Sewduth, Raj, Ferreira Tojais, Nancy, Jaspard, Béatrice, Reynaud, Annabel, Sohet, Fabien, Lacolley, Patrick, Allières, Cécile, Lamazière, Jean-Marie Daniel, Moreau, Catherine, Dufourcq, Pascale, Couffinhal, Thierry, Duplàa, Cécile

“…RATIONALE:A growing body of evidence supports the hypothesis that the Wnt/planar cell polarity (PCP) pathway regulates endothelial cell proliferation and…”
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Gli3 Regulation of Myogenesis Is Necessary for Ischemia-Induced Angiogenesis by Renault, Marie-Ange, Vandierdonck, Soizic, Chapouly, Candice, Yu, Yang, Qin, Gangjian, Metras, Alexandre, Couffinhal, Thierry, Losordo, Douglas W, Yao, Qinyu, Reynaud, Annabel, Jaspard-Vinassa, Béatrice, Belloc, Isabelle, Desgranges, Claude, Gadeau, Alain-Pierre

“…RATIONALE:A better understanding of the mechanism underlying skeletal muscle repair is required to develop therapies that promote tissue regeneration in…”
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Effects of human follicular fluid and high-density lipoproteins on early spermatozoa hyperactivation and cholesterol efflux by Hamdi, Safouane M., Vieitez, Gérard, Jaspard, Béatrice, Barbaras, Ronald, Perret, Bertrand, Mieusset, Roget, Parinaud, Jean, Collet, Xavier

“…The preovulatory human follicular fluid contains only HDLs as a lipoprotein class with a typically high proportion of preβ HDL. We first examined the role of…”
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PDZRN3 destabilizes endothelial cell-cell junctions through a PKCζ-containing polarity complex to increase vascular permeability by Sewduth, Raj N, Kovacic, Héléna, Jaspard-Vinassa, Béatrice, Jecko, Vincent, Wavasseur, Thomas, Fritsch, Nicolas, Pernot, Mathieu, Jeaningros, Sylvie, Roux, Etienne, Dufourcq, Pascale, Couffinhal, Thierry, Duplàa, Cécile

“…Endothelial cells serve as a barrier between blood and tissues. Maintenance of the endothelial cell barrier depends on the integrity of intercellular…”
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The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling by Sewduth, Raj N., Jaspard-Vinassa, Béatrice, Peghaire, Claire, Guillabert, Aude, Franzl, Nathalie, Larrieu-Lahargue, Frederic, Moreau, Catherine, Fruttiger, Marcus, Dufourcq, Pascale, Couffinhal, Thierry, Duplàa, Cécile

“…Development and stabilization of a vascular plexus requires the coordination of multiple signalling processes. Wnt planar cell polarity (PCP) signalling is…”
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GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways by VIGNERON, François, DOS SANTOS, Pierre, LEMOINE, Sandrine, BONNET, Maryline, TARIOSSE, Liliane, COUFFINHAL, Thierry, DUPLAA, Cécile, JASPARD-VINASSA, Béatrice

“…Ischaemic preconditioning (IPC) protects the heart against prolonged lethal ischaemia through a signalling cascade involving Akt, glycogen synthase kinase-3β…”
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Identification and Cloning of a Secreted Protein Related to the Cysteine-Rich Domain of Frizzled: Evidence for a Role in Endothelial Cell Growth Control by Duplàa, Cécile, Jaspard, Béatrice, Moreau, Catherine, D'Amore, Patricia A

“…We report the isolation of a cDNA, FrzA (frizzled in aorta; GenBank accession No. U85945), from bovine aortic endothelium. It is the bovine counterpart of the…”
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Desert Hedgehog Promotes Ischemia-Induced Angiogenesis by Ensuring Peripheral Nerve Survival by Renault, Marie-Ange, Chapouly, Candice, Yao, Qinyu, Larrieu-Lahargue, Frédéric, Vandierdonck, Soizic, Reynaud, Annabel, Petit, Myriam, Jaspard-Vinassa, Béatrice, Belloc, Isabelle, Traiffort, Elisabeth, Ruat, Martial, Duplàa, Cécile, Couffinhal, Thierry, Desgranges, Claude, Gadeau, Alain-Pierre

“…RATIONALE:Blood vessel growth and patterning have been shown to be regulated by nerve-derived signals. Desert hedgehog (Dhh), one of the Hedgehog family…”
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Structural and Functional Comparison of HDL From Homologous Human Plasma and Follicular Fluid: A Model for Extravascular Fluid by Jaspard, Beatrice, Fournier, Nathalie, Vieitez, Gerard, Atger, Veronique, Barbaras, Ronald, Vieu, Claude, Manent, Jeanine, Chap, Hugues, Perret, Bertrand, Collet, Xavier

“…In the preovulatory period, follicular fluid contains only HDL. Biochemical characterization of such lipoproteins showed that follicular fluid HDLs were…”
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Impact of Afterload Increase on Left Ventricular Myocardial Deformation Indices by Reant, Patricia, MD, PhD, Metras, Alexandre, MD, Detaille, Dominique, PhD, Reynaud, Annabel, PhD, Diolez, Philippe, PhD, Jaspard-Vinassa, Beatrice, PhD, Roudaut, Raymond, MD, Ouattara, Alexandre, MD, PhD, Barandon, Laurent, MD, PhD, Dos Santos, Pierre, MD, PhD, Lafitte, Stephane, MD, PhD

“…Background Left ventricular (LV) afterload could be associated with reduced myocardial contractility. The aim of this study was to evaluate the relative impact…”
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FrzA/sFRP-1, a secreted antagonist of the Wnt-Frizzled pathway, controls vascular cell proliferation in vitro and in vivo by EZAN, Jérome, LEROUX, Lionel, BARANDON, Laurent, DUFOURCQ, Pascale, JASPARD, Béatrice, MOREAU, Catherine, ALLIERES, Cécile, DARET, Danièle, COUFFINHAL, Thierry, DUPLAA, Cécile

“…FrzA, a member of the group of secreted frizzled related proteins (sFRP) that is expressed in the cardiovascular system, has been shown to antagonize the…”
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Fzd7 (Frizzled-7) Expressed by Endothelial Cells Controls Blood Vessel Formation Through Wnt/β-Catenin Canonical Signaling by Peghaire, Claire, Bats, Marie Lise, Sewduth, Raj, Jeanningros, Sylvie, Jaspard, Beatrice, Couffinhal, Thierry, Duplàa, Cécile, Dufourcq, Pascale

“…OBJECTIVE—Vessel formation requires precise orchestration of a series of morphometric and molecular events controlled by a multitude of angiogenic factors and…”
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Decrease of Pdzrn3 is required for heart maturation and protects against heart failure by Pernot, Mathieu, Jaspard-Vinassa, Béatrice, Abelanet, Alice, Rubin, Sebastien, Forfar, Isabelle, Jeanningros, Sylvie, Cetran, Laura, Yu, Murielle Han-Yee, Balse, Elise, Hatem, Stéphane, Dufourcq, Pascale, Couffinhal, Thierry, Duplàa, Cécile

“…Abstract Heart failure is the final common stage of most cardiopathies. Cardiomyocytes (CM) connect with others via their extremities by intercalated disk…”
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Identification of Mutated in colorectal cancer (MCC) protein as a novel partner of PDZRN3 during Blood brain barrier development by Delobel, Valentin, Vaurs, Juliette, Jaspard-Vinassa, Béatrice, Couffinhal, Thierry, Duplaa, Cecile

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