Search Results - "Jason Lai"

Nutrient Sensor in the Brain Directs the Action of the Brain-Gut Axis in Drosophila by Dus, Monica, Lai, Jason Sih-Yu, Gunapala, Keith M., Min, Soohong, Tayler, Timothy D., Hergarden, Anne C., Geraud, Eliot, Joseph, Christina M., Suh, Greg S.B.

“…Animals can detect and consume nutritive sugars without the influence of taste. However, the identity of the taste-independent nutrient sensor and the…”
Get full text

Biodiesel combustion: Advances in chemical kinetic modeling by Lai, Jason Y.W., Lin, Kuang C., Violi, Angela

“…Burgeoning global demand for energy has increased concerns about the fuel security issues and deleterious environmental impacts that result from the ubiquitous…”
Get full text

A glucose-sensing neuron pair regulates insulin and glucagon in Drosophila by Oh, Yangkyun, Lai, Jason Sih-Yu, Mills, Holly J., Erdjument-Bromage, Hediye, Giammarinaro, Benno, Saadipour, Khalil, Wang, Justin G., Abu, Farhan, Neubert, Thomas A., Suh, Greg S. B.

“…Although glucose-sensing neurons were identified more than 50 years ago, the physiological role of glucose sensing in metazoans remains unclear. Here we…”
Get full text

Towards a predictive model for polycyclic aromatic hydrocarbon dimerization propensity by Lowe, Jeffrey S., Lai, Jason Y.W., Elvati, Paolo, Violi, Angela

“…Soot particles are a significant pollutant formed as the result of incomplete combustion. Particle nucleation significantly impacts the formation and…”
Get full text

Optogenetic control of YAP cellular localisation and function by Toh, Pearlyn J Y, Lai, Jason K H, Hermann, Anke, Destaing, Olivier, Sheetz, Michael P, Sudol, Marius, Saunders, Timothy E

“…YAP, an effector of the Hippo signalling pathway, promotes organ growth and regeneration. Prolonged YAP activation results in uncontrolled proliferation and…”
Get full text

The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish by Lai, Jason K H, Collins, Michelle M, Uribe, Veronica, Jiménez-Amilburu, Vanesa, Günther, Stefan, Maischein, Hans-Martin, Stainier, Didier Y R

“…Cardiac trabeculation is a highly regulated process that starts with the delamination of compact layer cardiomyocytes. The Hippo signaling pathway has been…”
Get full text

Induction of interferon-stimulated genes and cellular stress pathways by morpholinos in zebrafish by Lai, Jason K.H., Gagalova, Kristina K., Kuenne, Carsten, El-Brolosy, Mohamed A., Stainier, Didier Y.R.

“…The phenotypes caused by morpholino-mediated interference of gene function in zebrafish are often not observed in the corresponding mutant(s). We took…”
Get full text

Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration by Lai, Shih-Lei, Marín-Juez, Rubén, Moura, Pedro Luís, Kuenne, Carsten, Lai, Jason Kuan Han, Tsedeke, Ayele Taddese, Guenther, Stefan, Looso, Mario, Stainier, Didier Yr

“…Zebrafish display a distinct ability to regenerate their heart following injury. However, this ability is not shared by another teleost, the medaka. In order…”
Get full text

Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells by Stone, Oliver A., El-Brolosy, Mohamed, Wilhelm, Kerstin, Liu, Xiaojing, Romão, Ana M., Grillo, Elisabetta, Lai, Jason K. H., Günther, Stefan, Jeratsch, Sylvia, Kuenne, Carsten, Lee, I-Ching, Braun, Thomas, Santoro, Massimo M., Locasale, Jason W., Potente, Michael, Stainier, Didier Y. R.

“…Despite their inherent proximity to circulating oxygen and nutrients, endothelial cells (ECs) oxidize only a minor fraction of glucose in mitochondria, a…”
Get full text

Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development by Astone, Matteo, Lai, Jason Kuan Han, Dupont, Sirio, Stainier, Didier Y. R., Argenton, Francesco, Vettori, Andrea

“…As effectors of the Hippo signaling cascade, YAP1 and TAZ are transcriptional regulators playing important roles in development, tissue homeostasis and cancer…”
Get full text

Periphery signals generated by Piezo-mediated stomach stretch and Neuromedin-mediated glucose load regulate the Drosophila brain nutrient sensor by Oh, Yangkyun, Lai, Jason Sih-Yu, Min, Soohong, Huang, Huai-Wei, Liberles, Stephen D., Ryoo, Hyung Don, Suh, Greg S.B.

“…Nutrient sensors allow animals to identify foods rich in specific nutrients. The Drosophila nutrient sensor, diuretic hormone 44 (DH44) neurons, helps the fly…”
Get full text

LCL Filter Design of a 50-kW 60-kHz SiC Inverter with Size and Thermal Considerations for Aerospace Applications by Yong Liu, Kye-Yak See, Shan Yin, Simanjorang, Rejeki, Chin Foong Tong, Nawawi, Arie, Lai, Jih-Sheng Jason

“…To achieve high power density, increasing the switching frequency of the power converter has become a trend. The LCL filter is a major contributor of the…”
Get full text

A High-Efficiency Quasi-Single-Stage Bridgeless Electrolytic Capacitor-Free High-Power AC-DC Driver for Supplying Multiple LED Strings in Parallel by Hongbo Ma, Lai, Jih-Sheng, Cong Zheng, Pengwei Sun

“…In order to design a high-efficiency, cost-effective, high-power driver for supplying multiple light-emitting diode (LED) strings in parallel, a novel…”
Get full text

Enhancing Structure Prediction and Design of Soluble and Membrane Proteins with Explicit Solvent-Protein Interactions by Lai, Jason K., Ambia, Joaquin, Wang, Yumeng, Barth, Patrick

“…Solvent molecules interact intimately with proteins and can profoundly regulate their structure and function. However, accurately and efficiently modeling…”
Get full text

Ab Initio Investigation of the Thermal Decomposition of n‑Butylcyclohexane by Akbar Ali, Mohamad, Dillstrom, V. Tyler, Lai, Jason Y. W, Violi, Angela

“…Environmental and energy security concerns have motivated an increased focus on developing clean, efficient combustors, which increasingly relies on insight…”
Get full text

Modeling and Control of Series-Series Compensated Inductive Power Transfer System by Zahid, Zaka Ullah, Dalala, Zakariya M., Cong Zheng, Rui Chen, Faraci, William Eric, Lai, Jih-Sheng Jason, Lisi, Gianpaolo, Anderson, David

“…In this paper, a T-equivalent circuit for loosely coupled transformer, which does not involve magnetic coupling, is presented. A detailed dynamic analysis…”
Get full text

An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function by Wang, Li, Pang, Kaifang, Han, Kihoon, Adamski, Carolyn J., Wang, Wei, He, Lingjie, Lai, Jason K., Bondar, Vitaliy V, Duman, Joseph G., Richman, Ronald, Tolias, Kimberley F., Barth, Patrick, Palzkill, Timothy, Liu, Zhandong, Holder, J. Lloyd, Zoghbi, Huda Y.

“…Genome sequencing has revealed an increasing number of genetic variations that are associated with neuropsychiatric disorders. Frequently, studies limit their…”
Get full text

Cascaded Dual-Buck Inverter With Reduced Number of Inductors by Khan, Ashraf Ali, Honnyong Cha, Lai, Jih-Sheng

“…A dual-buck inverter (DBI) possesses no shoot-through worries and can boost efficiency by using power MOSFETs. The main drawback of a DBI is the use of more…”
Get full text

A High-Efficiency MOSFET Transformerless Inverter for Nonisolated Microinverter Applications by Baifeng Chen, Bin Gu, Lanhua Zhang, Zahid, Zaka Ullah, Lai, Jih-Sheng Jason, Zhiling Liao, Ruixiang Hao

“…State-of-the-art low-power-level metal-oxide-semiconductor field-effect transistor (MOSFET)-based transformerless photovoltaic (PV) inverters can achieve high…”
Get full text

DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells by Lai, Jason K H, Toh, Pearlyn J Y, Cognart, Hamizah A, Chouhan, Geetika, Saunders, Timothy E

“…In a previous study, it was reported that Yap1 and Wwtr1 in zebrafish regulates the morphogenesis of the posterior body and epidermal fin fold (Kimelman et…”
Get full text