Search Results - "Jason G. Mezey"

Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium by Zhang, Haijun, Rostami, Mahboubeh R, Leopold, Philip L, Mezey, Jason G, O'Beirne, Sarah L, Strulovici-Barel, Yael, Crystal, Ronald G

“…Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease (COVID-19), a predominantly respiratory illness. The…”
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Point-of-care whole-exome sequencing of idiopathic male infertility by Fakhro, Khalid A, Elbardisi, Haitham, Arafa, Mohamed, Robay, Amal, Rodriguez-Flores, Juan L, Al-Shakaki, Alya, Syed, Najeeb, Mezey, Jason G, Abi Khalil, Charbel, Malek, Joel A, Al-Ansari, Abdulla, Al Said, Sami, Crystal, Ronald G

“…Purpose Nonobstructive azoospermia (NOA) affects 1% of the male population; however, despite state-of-the-art clinical assessment, for most patients the cause…”
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Ontogeny and Biology of Human Small Airway Epithelial Club Cells by Zuo, Wu-Lin, Shenoy, Sushila A, Li, Sheng, O'Beirne, Sarah L, Strulovici-Barel, Yael, Leopold, Philip L, Wang, Guoqing, Staudt, Michelle R, Walters, Matthew S, Mason, Christopher, Kaner, Robert J, Mezey, Jason G, Crystal, Ronald G

“…Little is known about human club cells, dome-shaped cells with dense cytoplasmic granules and microvilli that represent the major secretory cells of the human…”
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Circulating Endothelial Microparticles as a Measure of Early Lung Destruction in Cigarette Smokers by GORDON, Cynthia, GUDI, Kirana, KRAUSE, Anja, SACKROWITZ, Rachel, HARVEY, Ben-Gary, STRULOVICI-BAREL, Yael, MEZEY, Jason G, CRYSTAL, Ronald G

“…There is increasing evidence that emphysema is associated with primary loss of pulmonary capillary endothelium. Plasma levels of endothelial microparticles…”
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Identifying novel associations in GWAS by hierarchical Bayesian latent variable detection of differentially misclassified phenotypes by Shafquat, Afrah, Crystal, Ronald G, Mezey, Jason G

“…Heterogeneity in the definition and measurement of complex diseases in Genome-Wide Association Studies (GWAS) may lead to misdiagnoses and misclassification…”
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Four loci explain 83% of size variation in the horse by Makvandi-Nejad, Shokouh, Hoffman, Gabriel E, Allen, Jeremy J, Chu, Erin, Gu, Esther, Chandler, Alyssa M, Loredo, Ariel I, Bellone, Rebecca R, Mezey, Jason G, Brooks, Samantha A, Sutter, Nathan B

“…Horse body size varies greatly due to intense selection within each breed. American Miniatures are less than one meter tall at the withers while Shires and…”
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Dysregulation of club cell biology in idiopathic pulmonary fibrosis by Zuo, Wu-Lin, Rostami, Mahboubeh R, LeBlanc, Michelle, Kaner, Robert J, O'Beirne, Sarah L, Mezey, Jason G, Leopold, Philip L, Quast, Karsten, Visvanathan, Sudha, Fine, Jay S, Thomas, Matthew J, Crystal, Ronald G

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic fibrotic lung disease with an irreversible decline of lung function. "Bronchiolization",…”
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Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population by Yousri, Noha A., Fakhro, Khalid A., Robay, Amal, Rodriguez-Flores, Juan L., Mohney, Robert P., Zeriri, Hassina, Odeh, Tala, Kader, Sara Abdul, Aldous, Eman K., Thareja, Gaurav, Kumar, Manish, Al-Shakaki, Alya, Chidiac, Omar M., Mohamoud, Yasmin A., Mezey, Jason G., Malek, Joel A., Crystal, Ronald G., Suhre, Karsten

“…Metabolomics-genome-wide association studies (mGWAS) have uncovered many metabolic quantitative trait loci (mQTLs) influencing human metabolic individuality,…”
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RNA-Seq quantification of the human small airway epithelium transcriptome by Hackett, Neil R, Butler, Marcus W, Shaykhiev, Renat, Salit, Jacqueline, Omberg, Larsson, Rodriguez-Flores, Juan L, Mezey, Jason G, Strulovici-Barel, Yael, Wang, Guoqing, Didon, Lukas, Crystal, Ronald G

“…The small airway epithelium (SAE), the cell population that covers the human airway surface from the 6th generation of airway branching to the alveoli, is the…”
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Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations by Rodriguez-Flores, Juan L, Fakhro, Khalid, Agosto-Perez, Francisco, Ramstetter, Monica D, Arbiza, Leonardo, Vincent, Thomas L, Robay, Amal, Malek, Joel A, Suhre, Karsten, Chouchane, Lotfi, Badii, Ramin, Al-Nabet Al-Marri, Ajayeb, Abi Khalil, Charbel, Zirie, Mahmoud, Jayyousi, Amin, Salit, Jacqueline, Keinan, Alon, Clark, Andrew G, Crystal, Ronald G, Mezey, Jason G

“…An open question in the history of human migration is the identity of the earliest Eurasian populations that have left contemporary descendants. The Arabian…”
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Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease by Staudt, Michelle R, Buro-Auriemma, Lauren J, Walters, Matthew S, Salit, Jacqueline, Vincent, Thomas, Shaykhiev, Renat, Mezey, Jason G, Tilley, Ann E, Kaner, Robert J, Ho, Melisa W Y, Crystal, Ronald G

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Corneal confocal microscopy: Neurologic disease biomarker in Friedreich ataxia by Pagovich, Odelya E., Vo, Mary L., Zhao, Zoe Z., Petropoulos, Ioannis N., Yuan, Michelle, Lertsuwanroj, Buntitar, Ciralsky, Jessica, Lai, Edward, Kiss, Szilard, D'Amico, Donald J., Mezey, Jason G., Malik, Rayaz A., Crystal, Ronald G.

“…Objective Friedreich ataxia (FRDA), an autosomal recessive neurodegenerative disease caused by mutations in the gene encoding for the mitochondrial protein…”
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A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis by Logsdon, Benjamin A, Hoffman, Gabriel E, Mezey, Jason G

“…The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability…”
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Anti-hIgE gene therapy of peanut-induced anaphylaxis in a humanized murine model of peanut allergy by Pagovich, Odelya E., MD, Wang, Bo, MD, Chiuchiolo, Maria J., PhD, Kaminsky, Stephen M., PhD, Sondhi, Dolan, PhD, Jose, Clarisse L., BS, Price, Christina C., MD, Brooks, Sarah F., BSc, Mezey, Jason G., PhD, Crystal, Ronald G., MD

“…Background Peanuts are the most common food to provoke fatal or near-fatal anaphylactic reactions. Treatment with an anti-hIgE mAb is efficacious but requires…”
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Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2 by Ryan, Dorothy M, Vincent, Thomas L, Salit, Jacqueline, Walters, Matthew S, Agosto-Perez, Francisco, Shaykhiev, Renat, Strulovici-Barel, Yael, Downey, Robert J, Buro-Auriemma, Lauren J, Staudt, Michelle R, Hackett, Neil R, Mezey, Jason G, Crystal, Ronald G

“…Genome-wide association studies (GWAS) and candidate gene studies have identified a number of risk loci associated with the smoking-related disease COPD, a…”
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Persistence of circulating endothelial microparticles in COPD despite smoking cessation by Strulovici-Barel, Yael, Staudt, Michelle R, Krause, Anja, Gordon, Cynthia, Tilley, Ann E, Harvey, Ben-Gary, Kaner, Robert J, Hollmann, Charleen, Mezey, Jason G, Bitter, Hans, Pillai, Sreekumar G, Hilton, Holly, Wolff, Gerhard, Stevenson, Christopher S, Visvanathan, Sudha, Fine, Jay S, Crystal, Ronald G

“…Increasing evidence links COPD pathogenesis with pulmonary capillary apoptosis. We previously demonstrated that plasma levels of circulating microparticles…”
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POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes by Zhou, Haixia, Brekman, Angelika, Zuo, Wu-Lin, Ou, Xuemei, Shaykhiev, Renat, Agosto-Perez, Francisco J, Wang, Rui, Walters, Matthew S, Salit, Jacqueline, Strulovici-Barel, Yael, Staudt, Michelle R, Kaner, Robert J, Mezey, Jason G, Crystal, Ronald G, Wang, Guoqing

“…In the process of seeking novel lung host defense regulators by analyzing genome-wide RNA sequence data from normal human airway epithelium, we detected…”
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Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation by Wang, Guoqing, Wang, Rui, Strulovici-Barel, Yael, Salit, Jacqueline, Staudt, Michelle R, Ahmed, Joumana, Tilley, Ann E, Yee-Levin, Jenny, Hollmann, Charleen, Harvey, Ben-Gary, Kaner, Robert J, Mezey, Jason G, Sridhar, Sriram, Pillai, Sreekumar G, Hilton, Holly, Wolff, Gerhard, Bitter, Hans, Visvanathan, Sudha, Fine, Jay S, Stevenson, Christopher S, Crystal, Ronald G

“…Even after quitting smoking, the risk of the development of chronic obstructive pulmonary disease (COPD) and lung cancer remains significantly higher compared…”
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Cell-specific expression of lung disease risk-related genes in the human small airway epithelium by Zuo, Wu-Lin, Rostami, Mahboubeh R, Shenoy, Shushila A, LeBlanc, Michelle G, Salit, Jacqueline, Strulovici-Barel, Yael, O'Beirne, Sarah L, Kaner, Robert J, Leopold, Philip L, Mezey, Jason G, Schymeinsky, Juergen, Quast, Karsten, Visvanathan, Sudha, Fine, Jay S, Thomas, Matthew J, Crystal, Ronald G

“…The human small airway epithelium (SAE) plays a central role in the early events in the pathogenesis of most inherited and acquired lung disorders. Little is…”
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Waterpipe smoking induces epigenetic changes in the small airway epithelium by Walters, Matthew S, Salit, Jacqueline, Ju, Jin Hyun, Staudt, Michelle R, Kaner, Robert J, Rogalski, Allison M, Sodeinde, Teniola B, Rahim, Riyaad, Strulovici-Barel, Yael, Mezey, Jason G, Almulla, Ahmad M, Sattar, Hisham, Mahmoud, Mai, Crystal, Ronald G

“…Waterpipe (also called hookah, shisha, or narghile) smoking is a common form of tobacco use in the Middle East. Its use is becoming more prevalent in Western…”
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