Search Results - "Jasmine, Farzana"
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Association of KRAS Mutation and Gene Pathways in Colorectal Carcinoma: A Transcriptome- and Methylome-Wide Study and Potential Implications for Therapy
Published in International journal of molecular sciences (01-08-2024)“…Kirsten Rat Sarcoma ( ) is the most commonly mutated oncogene in colorectal carcinoma (CRC). We have previously reported the interactions between…”
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The Association Between Smoking and Gut Microbiome in Bangladesh
Published in Nicotine & tobacco research (16-07-2020)“…Abstract Introduction Epidemiological studies that investigate alterations in the gut microbial composition associated with smoking are lacking. This study…”
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Co-occurring expression and methylation QTLs allow detection of common causal variants and shared biological mechanisms
Published in Nature communications (23-02-2018)“…Inherited genetic variation affects local gene expression and DNA methylation in humans. Most expression quantitative trait loci ( cis -eQTLs) occur at the…”
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A Transcriptome and Methylome Study Comparing Tissues of Early and Late Onset Colorectal Carcinoma
Published in International journal of molecular sciences (17-11-2022)“…There is an increase in the incidence of early onset colorectal carcinoma (EOCRC). To better understand if there is any difference in molecular pathogenesis of…”
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Association of Arsenic Exposure with Whole Blood DNA Methylation: An Epigenome-Wide Study of Bangladeshi Adults
Published in Environmental health perspectives (01-05-2019)“…Arsenic exposure affects [Formula: see text] people worldwide, including [Formula: see text] in Bangladesh. Arsenic exposure increases the risk of cancer and…”
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Urinary arsenic and relative telomere length in 5–7 year old children in Bangladesh
Published in Environment international (01-11-2021)“…•Early childhood is a critical period for telomere biology.•Prior studies of urinary As and telomere length in children have had mixed findings.•We examined…”
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Pathways Related to Colon Inflammation Are Associated with Colorectal Carcinoma: A Transcriptome- and Methylome-Wide Study
Published in Cancers (26-05-2023)“…The association of chronic inflammation with colorectal carcinoma (CRC) development is well known in ulcerative colitis (UC). However, the role of inflammatory…”
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Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal
Published in Journal of medical genetics (01-01-2018)“…Leucocyte telomere length (TL) is a potential biomarker of ageing and risk for age-related disease. Leucocyte TL is heritable and shows substantial differences…”
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Arsenic exposure from drinking water and endothelial dysfunction in Bangladeshi adolescents
Published in Environmental research (15-05-2022)“…Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide, with ∼80% of CVD-related deaths occurring in low- and middle-income…”
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Gene-specific differential DNA methylation and chronic arsenic exposure in an epigenome-wide association study of adults in Bangladesh
Published in Environmental health perspectives (01-01-2015)“…Inorganic arsenic is one of the most common naturally occurring contaminants found in the environment. Arsenic is associated with a number of health outcomes,…”
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Maternal cigarette smoking during pregnancy and offspring DNA methylation in midlife
Published in Epigenetics (01-02-2018)“…Maternal smoking in pregnancy (MSP) has been associated with DNA methylation in specific CpG sites (CpGs) in infants and children. We investigated whether MSP,…”
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Occupational pesticide exposure and subclinical hypothyroidism among male pesticide applicators
Published in Occupational and environmental medicine (London, England) (01-02-2018)“…ObjectivesAnimal studies suggest that exposure to pesticides may alter thyroid function; however, few epidemiologic studies have examined this association. We…”
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Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians
Published in PLoS genetics (01-12-2014)“…A large fraction of human genes are regulated by genetic variation near the transcribed sequence (cis-eQTL, expression quantitative trait locus), and many…”
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Rare, Protein-Altering Variants in AS3MT and Arsenic Metabolism Efficiency: A Multi-Population Association Study
Published in Environmental health perspectives (01-04-2021)“…Common genetic variation in the arsenic methyltransferase ( ) gene region is known to be associated with arsenic metabolism efficiency (AME), measured as the…”
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Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh
Published in PLoS genetics (01-02-2012)“…Arsenic contamination of drinking water is a major public health issue in many countries, increasing risk for a wide array of diseases, including cancer. There…”
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The role of gut microbiome and its interaction with arsenic exposure in carotid intima-media thickness in a Bangladesh population
Published in Environment international (01-02-2019)“…Emerging data suggest that inorganic arsenic exposure and gut microbiome are associated with the risk of cardiovascular disease. The gut microbiome may modify…”
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Association of Microsatellite Instability and Gene Expression Profile in Colorectal Carcinoma and Potential Implications for Therapy
Published in Medicina (Kaunas, Lithuania) (20-02-2024)“…In sporadic colorectal carcinomas (CRC), microsatellite instability (MSI) pathways play important roles. Previously, we showed differences in DNA methylation…”
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Interaction between Microsatellite Instability (MSI) and Tumor DNA Methylation in the Pathogenesis of Colorectal Carcinoma
Published in Cancers (01-10-2021)“…In colorectal cancer (CRC), the role of microsatellite instability (MSI) is well known. In a genome-wide scale, for the first time, we explored whether…”
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The contribution of parent-to-offspring transmission of telomeres to the heritability of telomere length in humans
Published in Human genetics (01-01-2019)“…Leukocyte telomere length (LTL) is a heritable trait with two potential sources of heritability ( h 2 ): inherited variation in non-telomeric regions (e.g.,…”
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A missense variant in FTCD is associated with arsenic metabolism and toxicity phenotypes in Bangladesh
Published in PLoS genetics (20-03-2019)“…Inorganic arsenic (iAs) is a carcinogen, and exposure to iAs via food and water is a global public health problem. iAs-contaminated drinking water alone…”
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