Search Results - "Jasmer, Douglas P."

Intestinal cell diversity and treatment responses in a parasitic nematode at single cell resolution by Tyagi, Rahul, Rosa, Bruce A, Swain, Amanda, Artyomov, Maxim N, Jasmer, Douglas P, Mitreva, Makedonka

“…Parasitic nematodes, significant pathogens for humans, animals, and plants, depend on diverse organ systems for intra-host survival. Understanding the cellular…”
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The draft genome of the parasitic nematode Trichinella spiralis by Mitreva, Makedonka, Wilson, Richard K, Jasmer, Douglas P, Zarlenga, Dante S, Wang, Zhengyuan, Abubucker, Sahar, Martin, John, Taylor, Christina M, Yin, Yong, Fulton, Lucinda, Minx, Pat, Yang, Shiaw-Pyng, Warren, Wesley C, Fulton, Robert S, Bhonagiri, Veena, Zhang, Xu, Hallsworth-Pepin, Kym, Clifton, Sandra W, McCarter, James P, Appleton, Judith, Mardis, Elaine R

“…Richard Wilson and colleagues report the genome sequence of Trichinella spiralis , a food-borne parasitic nematode that diverged early in the evolution of the…”
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Omics Driven Understanding of the Intestines of Parasitic Nematodes by Jasmer, Douglas P, Rosa, Bruce A, Tyagi, Rahul, Mitreva, Makedonka

“…The biological and molecular complexity of nematodes has impeded research on development of new therapies for treatment and control. We have focused on the…”
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Genome-wide tissue-specific gene expression, co-expression and regulation of co-expressed genes in adult nematode Ascaris suum by Rosa, Bruce A, Jasmer, Douglas P, Mitreva, Makedonka

“…Caenorhabditis elegans has traditionally been used as a model for studying nematode biology, but its small size limits the ability for researchers to perform…”
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Cell Death and Transcriptional Responses Induced in Larvae of the Nematode Haemonchus contortus by Toxins/Toxicants with Broad Phylogenetic Efficacy by Jasmer, Douglas P, Rosa, Bruce A, Mitreva, Makedonka

“…Establishing methods to investigate treatments that induce cell death in parasitic nematodes will promote experimental approaches to elucidate mechanisms and…”
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De novo identification of toxicants that cause irreparable damage to parasitic nematode intestinal cells by Jasmer, Douglas P, Rosa, Bruce A, Tyagi, Rahul, Bulman, Christina A, Beerntsen, Brenda, Urban, Jr, Joseph F, Sakanari, Judy, Mitreva, Makedonka

“…Efforts to identify new drugs for therapeutic and preventive treatments against parasitic nematodes have gained increasing interest with expanding pathogen…”
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Rapid determination of nematode cell and organ susceptibility to toxic treatments by Jasmer, Douglas P., Rosa, Bruce A., Tyagi, Rahul, Mitreva, Makedonka

“…In research focused on the intestine of parasitic nematodes, we recently identified small molecule inhibitors toxic to intestinal cells of larval Ascaris suum…”
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Peptidases compartmentalized to the Ascaris suum intestinal lumen and apical intestinal membrane by Jasmer, Douglas P, Rosa, Bruce A, Mitreva, Makedonka

“…The nematode intestine is a tissue of interest for developing new methods of therapy and control of parasitic nematodes. However, biological details of…”
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Pan-Nematoda Transcriptomic Elucidation of Essential Intestinal Functions and Therapeutic Targets With Broad Potential by Wang, Qi, Rosa, Bruce A., Jasmer, Douglas P., Mitreva, Makedonka

“…The nematode intestine is continuous with the outside environment, making it easily accessible to anthelmintics for parasite control, but the development of…”
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Intestinal transcriptomes of nematodes: comparison of the parasites Ascaris suum and Haemonchus contortus with the free-living Caenorhabditis elegans by Yin, Yong, Martin, John, Abubucker, Sahar, Scott, Alan L, McCarter, James P, Wilson, Richard K, Jasmer, Douglas P, Mitreva, Makedonka

“…The nematode intestine is a major organ responsible for nutrient digestion and absorption; it is also involved in many other processes, such as reproduction,…”
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Functional and Phylogenetic Characterization of Proteins Detected in Various Nematode Intestinal Compartments[S] by Rosa, Bruce A., Townsend, Reid, Jasmer, Douglas P., Mitreva, Makedonka

“…The parasitic nematode intestine is responsible for nutrient digestion and absorption, and many other processes essential for reproduction and survival, making…”
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Compartmentalization of functions and predicted miRNA regulation among contiguous regions of the nematode intestine by Gao, Xin, Tyagi, Rahul, Magrini, Vincent, Ly, Amy, Jasmer, Douglas P., Mitreva, Makedonka

“…The intestine of parasitic nematodes has proven an important target for therapies aimed at prevention and treatment of diseases caused by these pathogens in…”
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Direct experimental manipulation of intestinal cells in Ascaris suum, with minor influences on the global transcriptome by Rosa, Bruce A., McNulty, Samantha N., Mitreva, Makedonka, Jasmer, Douglas P.

“…[Display omitted] •Direct delivery of treatments to Ascaris suum intestinal lumen and apical membrane.•Derivation of optimal methods for direct delivery of…”
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A tissue specific approach for analysis of membrane and secreted protein antigens from Haemonchus contortus gut and its application to diverse nematode species by Rehman, Abdur, P. Jasmer, Douglas

“…General methods to conduct tissue specific analysis are largely lacking for nematodes. An approach is described that focused on isolation of membrane and…”
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Direct immunization of the abomasum or rectum of goats induces local lymph node responses against Haemonchus contortus mucosal antigens by Jasmer, Douglas P, Brown, Wendy C, Parish, Steven

“…Abstract We investigated several methods to immunize the abomasum (fourth and gastric stomach) of kid goats by direct (abomasal) or distal (rectal or nasal)…”
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Parasitic nematode interactions with mammals and plants by JASMER, Douglas P, GOVERSE, Aska, SMANT, Geert

“…Parasitic nematodes that infect humans, animals, and plants cause serious diseases that are deleterious to human health and agricultural productivity. Chemical…”
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Parasitic nematodes—From genomes to control by Mitreva, Makedonka, Zarlenga, Dante S., McCarter, James P., Jasmer, Douglas P.

“…The diseases caused by parasitic nematodes in domestic and companion animals are major factors that decrease production and quality of the agricultural…”
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Trichinella spiralis-Infected Muscle Cells: Abundant RNA Polymerase II in Nuclear Speckle Domains Colocalizes with Nuclear Antigens by Yao, C, Jasmer, D P

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Effect of heat treatment on viability of Taenia hydatigena eggs by Buttar, Birpal S., Nelson, Mark L., Busboom, Jan R., Hancock, Dale D., Walsh, Douglas B., Jasmer, Douglas P.

“…[Display omitted] ► Heat treatment of Taenia hydatigena eggs for 5min. ► In vitro and in vivo analysis of viabilities. ► In vitro reduction in viability of…”
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A unique Babesia bovis spherical body protein is conserved among geographic isolates and localizes to the infected erythrocyte membrane by Ruef, Barbara J, Dowling, Susan C, Conley, Patrick G, Perryman, Lance E, Brown, Wendy C, Jasmer, Douglas P, Rice-Ficht, Allison C

“…Using monoclonal antibody (mAb) 70/52.9, generated from a Babesia bovis fraction enriched for spherical body organelles, we have identified a 135-kDa protein…”
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