Search Results - "Jasko, M. V."

5-Alkyloxymethyl Derivatives of 2ʹ-Deoxyuridine Bearing 2,4-Dinitrophenyl and Dansyl Groups: Synthesis and Antibacterial Activity by Makarov, D. A., Oskolsky, I. A., Jasko, M. V., Solyev, P. N., Vasilyeva, B. F., Demiankova, M. V., Efremenkova, O. V., Kochetkov, S. N., Alexandrova, L. A.

“…Condensation of 3ʹ,5ʹ-di- O -acetyl-5-bromomethyl-2ʹ-deoxyuridine with 6-trifluoroacetylaminohexan1-ol yielded…”
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Long-Chain Free Fatty Acids Influence Lipid Accumulation, Lysosome Activation and Glycolytic Shift in Various Cells In Vitro by Vishnyakova, K. S., Popov, K. V., Pan, X., Jasko, M. V., Yegorov, Y. E.

“…Hydrophobic molecules may be toxic when present in excess. When dissolved in membranes, hydrophobic molecules disrupt membrane function. Studies on the effects…”
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Glycol and Phosphate Depot Forms of 4- and/or 5-Modified Nucleosides Exhibiting Antibacterial Activity by Negrya, S. D., Jasko, M. V., Makarov, D. A., Solyev, P. N., Karpenko, I. L., Shevchenko, O. V., Chekhov, O. V., Glukhova, A. A., Vasilyeva, B. F., Efimenko, T. A., Sumarukova, I. G., Efremenkova, O. V., Kochetkov, S. N., Alexandrova, L. A.

“…Resistance developed to the majority of drugs used to treat infectious diseases warrants the design of new compounds effective against drug-resistant strains…”
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A new approach to the synthesis of optically active alkylated adenine derivatives by Zakirova, N.F., Shipitsyn, A.V., Belanov, E.F., Jasko, M.V.

“…A new synthesis of chiral acyclic nucleoside and nucleotide analogues starting from d(−)- or l(+)-riboses was proposed. Antiviral properties of the synthesized…”
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Structural-functional relationships between terminal deoxynucleotidyltransferase and 5'-triphosphates of nucleoside analogs by Kukhanova, M K, Ivanov, A V, Jasko, M V

“…Substrate properties of nucleoside 5'-triphosphate (NTP) analogs, namely, 5'-triphosphates of L- and D-arabinonucleosides (D-FIAUTP, D-FMAUTP, and L-FMAUTP),…”
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Study of Antiherpetic Efficiency of Phosphite of Acycloguanosine Ableto Over come the Barrier of Resistance to Acyclovir by Andronova, V L, Jasko, M V, Kukhanova, M K, Galegov, G A, Skoblov, Yr S, Kochetkov, S N

“…As has been shown previously, phosphite of acycloguanosine (Hp-ACG) exhibits equal efficacy against ACV-sensitive and ACV-resistant HSV-1 strains in cell…”
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Phosphoramidate derivatives of acyclovir, inhibitors of herpes virus replication by Zakirova, N. F., Shipitsyn, A. V., Jasko, M. V., Kochetkov, S. N.

“…A series of new acyclovir phosphoramidates—potential antiviral agents against resistant strains of herpes virus—was synthesized. Of several approaches used for…”
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Research of suppression of the herpes simplex virus reproduction with drug resistance by combination phosphite of acycloguanosine with some antiherpetic drugs by Andronova, V L, Jasko, M V, Kukhanova, M K, Skoblov, Yu S, Deryabin, P G, Galegov, G A

“…The activity of the phosphite of acycloguanosine (P-ACG) and six antivirals was tested individually and in double and triple combinations on two strains of the…”
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Synthesis and antiherpetic activity of (Z)- and (E)-9-(3-phosphonomethoxyprop-1-en-yl)adenines by Ivanov, A. V., Andronova, V. L., Galegov, G. A., Jasko, M. V.

“…The isomeric (Z)- and (E)-9-(3-phosphonomethoxyprop-1-en-yl)adenines were synthesized. The stereoselectivity of double bond formation was studied by variation…”
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Aryl-Containing Esters Of Triphosphoric Acid As Substrates Of Terminal Deoxynucleotidyl Transferase by Khandazhinskaya, A. L., Matyugina, E. S., Alexandrova, L. A., Shirokova, E. A., Kukhanova, M. K., Jasko, M. V.

“…A new group of terminal deoxynucleotidyltransferase (TDT) substrates, namely, non-nucleoside triphosphates (NNTP) bearing 5-substituted 2,4-dinitrophenyl…”
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Terminal deoxynucleotidyl transferase: catalysis of DNA (oligodeoxynucleotide) phosphorylation by Krayevsky, Alexander A., Victorova, Lyubov S., Arzumanov, Andrey A., Jasko, Maxim V.

“…The phosphorylation and phosphonylation of the 3′-hydroxyl of oligodeoxynucleotide 3′-termini (oligodeoxynucleotidyl kinase activity) catalyzed by calf thymus…”
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Terminal deoxynucleotidyl transferase catalyzes the reaction of DNA phosphorylation by Arzumanov, A A, Victorova, L S, Jasko, M V, Yesipov, D S, Krayevsky, A A

“…The reaction of phosphorylation and phosphonylation of an oligodeoxynucleotide 3'-terminal hydroxyl (oligodeoxynucleotidyl kinase activity) catalyzed by calf…”
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2′-Deoxynucleoside 5′-triphosphates modified at α-, β- and γ-phosphates as substrates for DNA polymerases by Alexandrova, Ludmila A., Skoblov, Alexander Yu, Jasko, Maxim V., Victorova, Lyubov S., Krayevsky, Alexander A.

“…Replacement of α-, β- and γ-phosphate groups in 2′-deoxynucleoside 5′-triphosphates (dNTP) with phosphonate groups yields a new set of dNTP mimics with…”
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Proliferating Cell Nuclear Antigen Promotes Misincorporation Catalyzed by Calf Thymus DNA Polymerase δ by Mozzherin, Dmitry Ju, McConnell, Maeve, Jasko, Maxim V., Krayevsky, Alexander A., Tan, Cheng-Keat, Downey, Kathleen M., Fisher, Paul A.

“…A proliferating cell nuclear antigen (PCNA)-dependent complex, detectable after nondenaturing polyacrylamide gel electrophoresis, is formed between calf thymus…”
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New Nonnucleoside Substrates for Terminal Deoxynucleotidyl Transferase: Synthesis and Dependence of Substrate Properties on Structure by Khandazhinskaya, A. L., Kukhanova, M. K., Jasko, M. V.

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Glycol and Phosphate Depot Forms of 4- and/or 5-Modified Nucleosides Exhibiting Antibacterial Activity by Negrya, S D, Jasko, M V, Makarov, D A, Solyev, P N, Karpenko, I L, Shevchenko, O V, Chekhov, O V, Glukhova, A A, Vasilyeva, B F, Efimenko, T A, Sumarukova, I G, Efremenkova, O V, Kochetkov, S N, Alexandrova, L A

“…Resistance developed to the majority of drugs used to treat infectious diseases warrants the design of new compounds effective against drug-resistant strains…”
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Effect of triphosphate modifications in 2′-deoxynucleoside 5′-triphosphates on their specificity towards various DNA polymerases by Martynov, Boris I, Shirokova, Elena A, Jasko, Maxim V, Victorova, Lyubov S, Krayevsky, Alexander A

“…Some natural and glycon-modified dNTPs with β,γ-pyrophosphate substitution at the triphosphate residue were synthesized and studied to evaluate the effect of…”
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Synthesis and Antiherpetic Activity of Acyclovir Phosphonates by Karpenko, Inna L., Jasko, Maxim V., Andronova, Valeriya L., Ivanov, Alexander V., Kukhanova, Marina K., Galegov, Georgy A., Skoblov, Yury S.

“…Phosphonate derivatives of acyclovir containing phosphorous acid and ethoxycarbonylphosphonic acid residues as well as their isopropyl esters were prepared…”
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The Synthesis and Antiherpetic Activity of Acyclovir Phosphonate Esters by Jasko, M. V., Ulanova, N. Yu, Andronova, V. L., Ivanov, A. V., Karpenko, I. L., Kukhanova, M. K., Galegov, G. A., Skoblov, Yu. S.

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Novel 3‘-C/N-Substituted 2‘,3‘-β-d-Dideoxynucleosides as Potential Chemotherapeutic Agents. 1. Thymidine Derivatives:  Synthesis, Structure, and Broad Spectrum Antiviral Properties by Fedorov, Ivan I, Kazmina, Ema M, Gurskaya, Galina V, Jasko, Maxim V, Zavodnic, Valery E, Balzarini, Jan, De Clercq, Erik, Faraj, Abdesslem, Sommadossi, Jean-Pierre, Imbach, Jean-Louis, Gosselin, Gilles

“…A synthetic scheme for the 3‘-oxime derivatives 3E, 5E, 5Z, 7E and 7Z of 1-(2,3-dideoxy-β-d-glycero-pentofuranosyl)thymine and for…”
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