Search Results - "Jaskiewicz, E."

Recombinant forms of Gerbich blood group antigens: expression and purification by Jaskiewicz, E, Czerwinski, M, Colin, Y, Lisowska, E

“…Recombinant forms of normal glycophorin C (GPC), carrying the high frequency Gerbich blood group antigens, and its natural deletion mutants of Yus and Ge type…”
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Recombinant forms of glycophorin C as a tool for characterization of epitopes for new murine monoclonal antibodies with anti-glycophorin C specificity by Jaskiewicz, E., Czerwinski, M., Uchikawa, M., Murata, S., Miyazaki, T., Ikeda, H., Lisowska, E.

“…Summary Glycophorin C (GPC) and glycophorin D (GPD) are minor but important components of human RBC membranes. They carry the high‐frequency antigens Ge2, Ge3…”
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Two soluble glycosyltransferases glycosylate less efficiently in vivo than their membrane bound counterparts by Zhu, Guofen, Allende, Maria Laura, Jaskiewicz, Ewa, Qian, Rong, Darling, Douglas S., Worth, Christopher A., Colley, Karen J., Young, William W.

“…Many Golgi glycosyltransferases are type II membrane proteins which are cleaved to produce soluble forms that are released from cells. Cho and Cummings…”
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Cloned beta 1,4 N-acetylgalactosaminyltransferase synthesizes GA2 as well as gangliosides GM2 and GD2. GM3 synthesis has priority over GA2 synthesis for utilization of lactosylceramide substrate in vivo by Lutz, M.S., Jaskiewicz, E., Darling, D.S., Furukawa, K., Young, W.W.

“…Earlier studies reached conflicting conclusions as to the ability of the beta 1,4 N-acetylgalactosaminyltransferase (GalNAc-T) that synthesizes gangliosides…”
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Recombinant forms of myelin antigens expressed on CHO cells as a tool for identification of autoantibodies in serum of MS patients by Jaskiewicz, E, Michalowska-Wender, G, Wender, M

“…A contribution of B cells and autoantibodies has been demonstrated in MS leading to interest in the use of such autoantibodies as diagnostic or prognostic…”
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Characterization of the epitope recognized by a monoclonal antibody highly specific for blood group M antigen by Jaskiewicz, E, Moulds, J J, Kraemer, K, Goldstein, A S, Lisowska, E

“…The mouse monoclonal antibody M2A1 of IgG1 class, which is highly specific for blood group M antigen, was obtained and characterized by means of…”
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Retention of glycosyltransferases in the Golgi apparatus by Jaśkiewicz, E

“…A number of Golgi glycosyltransferases has been cloned to date. They all are membrane proteins and share the same type II topology, but they do not possess an…”
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Recombinant forms of myelin antigens expressed on Chinese hamster ovary (CHO) cells as a tool for identification of autoantibodies in serum of multiple sclerosis patients by Jaśkiewicz, Ewa, Michałowska-Wender, Grazyna, Pyszczek, Anna, Wender, Mieczysław

“…A contribution of B cells and autoantibodies has been demonstrated in MS leading to interest in the use of such autoantibodies as diagnostic or prognostic…”
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Expression of recombinant forms of human 21.5 kDa myelin basic protein and proteolipid protein in CHO cells by Jaśkiewicz, Ewa, Jedynak, Anna, Zioło, Ewa

“…MBP and PLP are major structural protein components of myelin. Both proteins play a functional role in formation of myelin sheath and in maintenance of its…”
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Mapping of peptidic epitopes of glycophorins A (GPA) and C (GPC) with peptides synthesized on plastic pins (Pepscan analysis) by Waśniowska, K., Jaśkiewicz, E., Czerwiński, M., Syper, D., Lisowska, E.

“…The peptidic epitopes of 12 anti-GPA and 4 anti-GPC antibodies were identified with the use of peptides synthesized on the pins. Most of the antibodies were…”
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Disulfide bonds of GM2 synthase homodimers. Antiparallel orientation of the catalytic domains by Li, J, Yen, T Y, Allende, M L, Joshi, R K, Cai, J, Pierce, W M, Jaskiewicz, E, Darling, D S, Macher, B A, Young, Jr, W W

“…GM2 synthase is a homodimer in which the subunits are joined by lumenal domain disulfide bond(s). To define the disulfide bond pattern of this enzyme, we…”
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Anti-M Monoclonal Antibodies Cross-Reacting With Variant Mg Antigen: An Example of Modulation of Antigenic Properties of Peptide by Its Glycosylation by Jaśkiewicz, Ewa, Czerwinski, Marcin, Syper, Danuta, Lisowska, Elwira

“…Some monoclonal antibodies (MoAbs) directed against blood group M-related epitope of glycophorin A (GPA) were found to agglutinate rare variant erythrocytes…”
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Fine specificities of murine anti-Mg monoclonal antibodies by Jaśkiewicz, Blanchard, Rasamoelisolo, Loirat, Moulds, Lisowska

“…The specificities of two murine anti‐Mg monoclonal IgG1 antibodies, 3B10 and 2D5, were determined by pepscan analysis. The peptides which correspond to various…”
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Beta 1,4 N-acetylgalactosaminyltransferase (GM2/GD2/GA2 synthase) forms homodimers in the endoplasmic reticulum: a strategy to test for dimerization of Golgi membrane proteins by Zhu, G, Jaskiewicz, E, Bassi, R, Darling, D S, Young, Jr, W W

“…Many Golgi membrane-bound glycosyltransferases exist as intermolecular disulfide bonded species, some of which have been demonstrated to be homodimers…”
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Anti-M monoclonal antibodies cross-reacting with variant Mg antigen: an example of modulation of antigenic properties of peptide by its glycosylation by Jaskiewicz, E, Czerwinski, M, Syper, D, Lisowska, E

“…Some monoclonal antibodies (MoAbs) directed against blood group M- related epitope of glycophorin A (GPA) were found to agglutinate rare variant erythrocytes…”
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Beta1,4-N-acetylgalactosaminyltransferase (GM2 synthase) is released from Golgi membranes as a neuraminidase-sensitive, disulfide-bonded dimer by a cathepsin D-like protease by Jaskiewicz, E, Zhu, G, Bassi, R, Darling, D S, Young, Jr, W W

“…Many Golgi membrane-bound glycosyltransferases are released from cells in a soluble form. To characterize this release process, we stably transfected Chinese…”
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Reevaluating the effect of Brefeldin A (BFA) on ganglioside synthesis: the location of GM2 synthase cannot be deduced from the inhibition of GM2 synthesis by BFA by Young, William W., Allende, Maria Laura, Jaskiewicz, Ewa

“…Brefeldin A reversibly disassembles the Golgi complex, causing mixing of the Golgi cisternae with the ER while the trans Golgi network persists as part of a…”
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Fine specificities of murine anti‐M g monoclonal antibodies by Jaśkiewicz, Blanchard, Rasamoelisolo, Loirat, Moulds, Lisowska

“…The specificities of two murine anti‐M g monoclonal IgG1 antibodies, 3B10 and 2D5, were determined by pepscan analysis. The peptides which correspond to…”
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Cloned beta 1,4N-acetylgalactosaminyltransferase: subcellular localization and formation of disulfide bonded species by Jaskiewicz, E, Zhu, G, Taatjes, D J, Darling, D S, Zwanzig, Jr, G E, Young, Jr, W W

“…Cloned human beta 1,4N-acetylgalactosaminyltransferase (GalNAcT) catalyzes the synthesis of the glycosphingolipids GM2, GD2, and gangliotriosylceramide. To…”
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Alloantibody anti-Gerbich: blood transfusion problems and family studies by Kuśnierz-Alejska, G, Seyfried, H, Jaśkiewicz, E, Janczarski, M

“…In a patient with myelodysplastic syndrom complement fixing IgG1 anti-Ge three weeks after Ge positive serologically compatible blood transfusion was found…”
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