Search Results - "Jaromin, Anna"

Perspectives for New and More Efficient Multifunctional Ligands for Alzheimer′s Disease Therapy by Zagórska, Agnieszka, Jaromin, Anna

“…Despite tremendous research efforts at every level, globally, there is still a lack of effective drugs for the treatment of Alzheimer′s disease (AD). The…”
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Antimalarials Targeting the Malaria Parasite Cation ATPase P. falciparum ATP4 (PfATP4) by Zagórska, Agnieszka, Jaromin, Anna

“…Malaria, caused by parasites of the Plasmodium species and transmitted through the bites of infected female Anopheles mosquitoes, is still a fatal and…”
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Coordination of fungal biofilm development by extracellular vesicle cargo by Zarnowski, Robert, Noll, Andrea, Chevrette, Marc G., Sanchez, Hiram, Jones, Ryley, Anhalt, Hanna, Fossen, Jen, Jaromin, Anna, Currie, Cameron, Nett, Jeniel E., Mitchell, Aaron, Andes, David R.

“…The fungal pathogen Candida albicans can form biofilms that protect it from drugs and the immune system. The biofilm cells release extracellular vesicles (EVs)…”
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Synthesis and Antioxidant Activity of Caffeic Acid Derivatives by Sidoryk, Katarzyna, Jaromin, Anna, Filipczak, Nina, Cmoch, Piotr, Cybulski, Marcin

“…A series of caffeic acid derivatives were synthesized via a modified Wittig reaction which is a very important tool in organic chemistry for the construction…”
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Candida albicans biofilm-induced vesicles confer drug resistance through matrix biogenesis by Zarnowski, Robert, Sanchez, Hiram, Covelli, Antonio S, Dominguez, Eddie, Jaromin, Anna, Bernhardt, Jörg, Mitchell, Kaitlin F, Heiss, Christian, Azadi, Parastoo, Mitchell, Aaron, Andes, David R

“…Cells from all kingdoms of life produce extracellular vesicles (EVs). Their cargo is protected from the environment by the surrounding lipid bilayer. EVs from…”
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The Comparison of MTT and CVS Assays for the Assessment of Anticancer Agent Interactions by Śliwka, Lidia, Wiktorska, Katarzyna, Suchocki, Piotr, Milczarek, Małgorzata, Mielczarek, Szymon, Lubelska, Katarzyna, Cierpiał, Tomasz, Łyżwa, Piotr, Kiełbasiński, Piotr, Jaromin, Anna, Flis, Anna, Chilmonczyk, Zdzisław

“…Multiple in vitro tests are widely applied to assess the anticancer activity of new compounds, including their combinations and interactions with other drugs…”
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Physicochemical Investigations of Chitosan-Based Hydrogels Containing Aloe Vera Designed for Biomedical Use by Drabczyk, Anna, Kudłacik-Kramarczyk, Sonia, Głąb, Magdalena, Kędzierska, Magdalena, Jaromin, Anna, Mierzwiński, Dariusz, Tyliszczak, Bożena

“…In this work, synthesis and investigations on chitosan-based hydrogels modified with Aloe vera juice are presented. These materials were synthesized by UV…”
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The Conjugates of Indolo[2,3- b ]quinoline as Anti-Pancreatic Cancer Agents: Design, Synthesis, Molecular Docking and Biological Evaluations by Cybulski, Marcin, Sidoryk, Katarzyna, Zaremba-Czogalla, Magdalena, Trzaskowski, Bartosz, Kubiszewski, Marek, Tobiasz, Joanna, Jaromin, Anna, Michalak, Olga

“…New amide conjugates of hydroxycinnamic acids (HCAs) and the known antineoplastic 5,11-dimethyl-5 -indolo[2,3- ]quinoline (DiMIQ), an analog of the natural…”
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Evaluation of the In Vitro Cytotoxic Activity of Caffeic Acid Derivatives and Liposomal Formulation against Pancreatic Cancer Cell Lines by Zaremba-Czogalla, Magdalena, Jaromin, Anna, Sidoryk, Katarzyna, Zagórska, Agnieszka, Cybulski, Marcin, Gubernator, Jerzy

“…Pancreatic cancer belongs to the most aggressive group of cancers, with very poor prognosis. Therefore, there is an important need to find more potent drugs…”
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Exploring the antiplatelet activity of serotonin 5-HT2A receptor antagonists bearing 6-fluorobenzo[d]isoxazol-3-yl)propyl) motif– as potential therapeutic agents in the prevention of cardiovascular diseases by Marcinkowska, Monika, Kubacka, Monika, Zagorska, Agnieszka, Jaromin, Anna, Fajkis-Zajaczkowska, Nikola, Kolaczkowski, Marcin

“…Small drug-like molecules that can block the function of serotonin 5-HT2A receptors have garnered considerable attention due to their ability to inhibit…”
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Drug Discovery and Development Targeting Dementia by Zagórska, Agnieszka, Czopek, Anna, Fryc, Monika, Jaromin, Anna, Boyd, Ben J

“…Dementia, most often associated with neurodegenerative diseases, affects millions of people worldwide, predominantly the elderly. Unfortunately, no treatment…”
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Nanoemulsion Stabilized by Safe Surfactin from Bacillus Subtilis as a Multifunctional, Custom-Designed Smart Delivery System by Lewińska, Agnieszka, Domżał-Kędzia, Marta, Jaromin, Anna, Łukaszewicz, Marcin

“…The developing field of bio-nanotechnology aims to advance colloidal research via the introduction of multifunctional nanoparticles to augment the dermal…”
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Synthesis, Molecular Docking and Antiplasmodial Activities of New Tetrahydro-β-Carbolines by Jaromin, Anna, Gryzło, Beata, Jamrozik, Marek, Parapini, Silvia, Basilico, Nicoletta, Cegła, Marek, Taramelli, Donatella, Zagórska, Agnieszka

“…Malaria is still one of the most dangerous infectious diseases and the emergence of drug resistant parasites only worsens the situation. A series of new…”
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Design and Development of a New Type of Hybrid PLGA/Lipid Nanoparticle as an Ursolic Acid Delivery System against Pancreatic Ductal Adenocarcinoma Cells by Markowski, Adam, Jaromin, Anna, Migdał, Paweł, Olczak, Ewa, Zygmunt, Adrianna, Zaremba-Czogalla, Magdalena, Pawlik, Krzysztof, Gubernator, Jerzy

“…Despite many attempts, trials, and treatment procedures, pancreatic ductal adenocarcinoma (PDAC) still ranks among the most deadly and treatment-resistant…”
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A Label-Free Cellular Proteomics Approach to Decipher the Antifungal Action of DiMIQ, a Potent Indolo[2,3- b ]Quinoline Agent, against Candida albicans Biofilms by Zarnowski, Robert, Jaromin, Anna, Zagórska, Agnieszka, Dominguez, Eddie G, Sidoryk, Katarzyna, Gubernator, Jerzy, Andes, David R

“…forms extremely drug-resistant biofilms, which present a serious threat to public health globally. Biofilm-based infections are difficult to treat due to the…”
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The Antidepressant-like Activity, Effects on Recognition Memory Deficits, Bioavailability, and Safety after Chronic Administration of New Dual-Acting Small Compounds Targeting Neuropsychiatric Symptoms in Dementia by Jastrzębska-Więsek, Magdalena, Kotańska, Magdalena, Grzeszczak, Aleksandra, Jaromin, Anna, Walczak, Maria, Partyka, Anna, Gdula-Argasińska, Joanna, Smolik, Magdalena, Zagórska, Agnieszka

“…This study aimed to extend the body of preclinical research on prototype dual-acting compounds combining the pharmacophores relevant for inhibiting cyclic…”
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Design, Synthesis, and In Vitro Antiproliferative Activity of Hydantoin and Purine Derivatives with the 4-Acetylphenylpiperazinylalkyl Moiety by Zagórska, Agnieszka, Czopek, Anna, Jaromin, Anna, Mielczarek-Puta, Magdalena, Struga, Marta, Stary, Dorota, Bajda, Marek

“…Cancer represents one of the most serious health problems and the second leading cause of death around the world. Heterocycles, due to their prevalence in…”
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Novel Liposomal Formulation of Baicalein for the Treatment of Pancreatic Ductal Adenocarcinoma: Design, Characterization, and Evaluation by Markowski, Adam, Zaremba-Czogalla, Magdalena, Jaromin, Anna, Olczak, Ewa, Zygmunt, Adrianna, Etezadi, Haniyeh, Boyd, Ben J, Gubernator, Jerzy

“…Pancreatic cancer (PC) is one of the deadliest cancers so there is an urgent need to develop new drugs and therapies to treat it. Liposome-based formulations…”
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Impact of N-Alkylamino Substituents on Serotonin Receptor (5-HTR) Affinity and Phosphodiesterase 10A (PDE10A) Inhibition of Isoindole-1,3-dione Derivatives by Czopek, Anna, Partyka, Anna, Bucki, Adam, Pawłowski, Maciej, Kołaczkowski, Marcin, Siwek, Agata, Głuch-Lutwin, Monika, Koczurkiewicz, Paulina, Pękala, Elżbieta, Jaromin, Anna, Tyliszczak, Bożena, Wesołowska, Anna, Zagórska, Agnieszka

“…In this study, a series of compounds derived from 4-methoxy-1 -isoindole-1,3(2 )-dione, potential ligands of phosphodiesterase 10A and serotonin receptors,…”
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The Development of the Innovative Synthesis Methodology of Albumin Nanoparticles Supported by Their Physicochemical, Cytotoxic and Hemolytic Evaluation by Kudłacik-Kramarczyk, Sonia, Drabczyk, Anna, Głąb, Magdalena, Gajda, Paweł, Czopek, Anna, Zagórska, Agnieszka, Jaromin, Anna, Gubernator, Jerzy, Makara, Agnieszka, Tyliszczak, Bożena

“…Many studies are being performed to develop effective carriers for controlled cytostatic delivery wherein albumin is a promising material due to its tendency…”
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