Search Results - "Jarolim, Stefanie"
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Saccharomyces cerevisiae genes involved in survival of heat shock
Published in G3 : genes - genomes - genetics (01-12-2013)“…The heat-shock response in cells, involving increased transcription of a specific set of genes in response to a sudden increase in temperature, is a highly…”
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Slow Growth and Increased Spontaneous Mutation Frequency in Respiratory Deficient afo1 - Yeast Suppressed by a Dominant Mutation in ATP3
Published in G3 : genes - genomes - genetics (01-12-2020)“…A yeast deletion mutation in the nuclear-encoded gene, , which codes for a mitochondrial ribosomal protein, led to slow growth on glucose, the inability to…”
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A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging
Published in Aging (Albany, NY.) (13-08-2010)“…The combination of functional genomics with next generation sequencing facilitates new experimental strategies for addressing complex biological phenomena…”
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Superoxide radicals have a protective role during H2O2 stress
Published in Molecular biology of the cell (15-09-2013)“…Reactive oxygen species (ROS) consist of potentially toxic, partly reduced oxygen species and free radicals. After H(2)O(2) treatment, yeast cells…”
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MMI1 ( YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria
Published in Biochimica et biophysica acta (01-05-2006)“…The yeast orthologue of mammalian TCTP is here proposed to be named Mmi1p ( microtubule and mitochondria interacting protein). This protein displays about 50%…”
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Superoxide radicals have a protective role during H 2 O 2 stress
Published in Molecular biology of the cell (15-09-2013)“…Reactive oxygen species (ROS) consist of potentially toxic, partly reduced oxygen species and free radicals. After H 2 O 2 treatment, yeast cells significantly…”
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The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1
Published in Aging (Albany, NY.) (13-07-2009)“…Yeast mother cell-specific aging constitutes a model of replicative aging as it occurs in stem cell populations of higher eukaryotes. Here, we present a new…”
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Involvement of oxidative stress response genes in redox homeostasis, the level of reactive oxygen species, and ageing in Saccharomyces cerevisiae
Published in FEMS yeast research (01-12-2005)“…Saccharomyces cerevisiae mutants lacking oxidative stress response genes were used to investigate which genes are required under normal aerobic conditions to…”
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A novel assay for replicative lifespan in Saccharomyces cerevisiae
Published in FEMS yeast research (01-11-2004)“…The replicative lifespan of Saccharomyces cerevisiae is determined by both genetic and environmental factors. Many of the same factors determine the lifespan…”
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A comparison of the aging and apoptotic transcriptome of Saccharomyces cerevisiae
Published in FEMS yeast research (01-12-2005)“…In this paper, we present the results of global transcript analysis by the microarray technique of senescent and apoptotic yeast cells. We compared young…”
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The role of respiration, reactive oxygen species and oxidative stress in mother cell-specific ageing of yeast strains defective in the RAS signalling pathway
Published in FEMS yeast research (01-11-2004)“…We show that the dominant activated allele of the yeast RAS gene, RAS2 ala18,val19 , led to redox imbalance in exponential-phase cells and to excretion of…”
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Evidence for ORC-dependent repression of budding yeast genes induced by starvation and other stresses
Published in FEMS yeast research (01-08-2006)“…The highly conserved origin recognition complex (ORC) is required for repressing genes in the silent mating type loci of budding yeast. Here we report that at…”
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