Search Results - "Jarolím, P"

Multicenter analytical evaluation of a high-sensitivity troponin T assay by Saenger, A.K., Beyrau, R., Braun, S., Cooray, R., Dolci, A., Freidank, H., Giannitsis, E., Gustafson, S., Handy, B., Katus, H., Melanson, S.E., Panteghini, M., Venge, P., Zorn, M., Jarolim, P., Bruton, D., Jarausch, J., Jaffe, A.S.

“…High-sensitivity cardiac troponin assays are being introduced clinically for earlier diagnosis of acute myocardial infarction (AMI). We evaluated the…”
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Detection of acute changes in circulating troponin in the setting of transient stress test-induced myocardial ischaemia using an ultrasensitive assay: results from TIMI 35 by Sabatine, Marc S., Morrow, David A., de Lemos, James A., Jarolim, Petr, Braunwald, Eugene

“…Aims To determine whether an ultrasensitive assay can permit quantification of changes in circulating cardiac troponin (Tn) in the setting of stress…”
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Filtration Markers, Cardiovascular Disease, Mortality, and Kidney Outcomes in Stable Kidney Transplant Recipients: The FAVORIT Trial by Foster, M. C., Weiner, D. E., Bostom, A. G., Carpenter, M. A., Inker, L. A., Jarolim, P., Joseph, A. A., Kusek, J. W., Pesavento, T., Pfeffer, M. A., Rao, M., Solomon, S. D., Levey, A. S.

“…Cystatin C and beta‐2‐microglobulin (B2M) are filtration markers associated with adverse outcomes in nontransplant populations, sometimes with stronger…”
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The dynamics of gene expression in human lung microvascular endothelial cells after stimulation with inflammatory cytokines by Zachlederová, M, Jarolím, P

“…Vascular endothelium plays an essential role in the pathogenesis of vasoocclusion. The changes in the endothelial cell function can be triggered by changes in…”
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Clinical expression and laboratory detection of red blood cell membrane protein mutations by Palek, J, Jarolim, P

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Incomplete distal renal tubular acidosis coinherited with a mutation in the band 3 (AE1) gene by Rysavá, R, Tesar, V, Jirsa, Jr, M, Brabec, V, Jarolím, P

“…Band 3 (anion exchanger 1, AE1) is one of the most abundant proteins of the erythrocyte membrane. We have previously characterized twenty AE1 gene defects…”
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Combination of two mutant alpha spectrin alleles underlies a severe spherocytic hemolytic anemia by Wichterle, H, Hanspal, M, Palek, J, Jarolim, P

“…We studied a patient with a severe spherocytic hemolytic anemia without family history of spherocytosis. Analysis of patient's erythrocyte membrane proteins…”
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Transpulmonary proteome gradients identify inflammatory pathways involved in the development of pulmonary vasculopathy in heart failure by Melenovsky, V, Jarolim, P, Kutilkova, E, Jenca, D, Binova, J, Benes, J, Al-Hiti, H, Miklovic, M, Borlaug, B A

“…Abstract Background Some, but not all, patients with heart failure (HF) develop pulmonary vascular disease (PVD), which contributes to poor prognosis…”
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Characterization of Seven Low Incidence Blood Group Antigens Carried by Erythrocyte Band 3 Protein by Jarolim, P., Rubin, H.L., Zakova, D., Storry, J., Reid, M.E.

“…Recent studies have demonstrated that band 3 carries antigens of the Diego blood group system and have elucidated the molecular basis of several previously…”
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Circulating beta-hydroxybutyrate levels in advanced HFrEF: the determinants and prognostic impact by Melenovsky, V, Benes, J, Monzo, L, Kotrc, M, Reichenbach, A, Jurcova, I, Kovar, J, Jarolim, P, Kautzner, J

“…Abstract Background Beta-hydroxybutyrate (BOHB) is the main ketone body and is generated mainly in the liver during states of exessive fatty acid (FA)…”
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Deletion in Erythrocyte Band 3 Gene in Malaria-Resistant Southeast Asian Ovalocytosis by Jarolim, P, Palek, J, Amato, D, Hassan, K, Sapak, P, Nurse, G T, Rubin, H L, Zhai, S, Sahr, K E, Liu, S C

“…Southeast Asian ovalocytosis (SAO) is a hereditary condition that is widespread in parts of Southeast Asia. The ovalocytic erythrocytes are rigid and resistant…”
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Characterization of the underlying molecular defect in hereditary spherocytosis associated with spectrin deficiency by HASSOUN, H, VASSILIADIS, J. N, MURRAY, J, NJOLSTAD, P. R, ROGUS, J. J, BALLAS, S. K, SCHAFFER, F, JAROLIM, P, BRABEC, V, PALEK, J

“…Several subsets of patients with hereditary spherocytosis (HS) have been defined based on the specific red blood cell membrane protein deficiencies involving…”
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Lipoprotein(a) and the risk of major adverse limb events in patients with stable atherosclerotic vascular disease by Bonaca, M, Morrow, D A, Giugliano, R P, Scirica, B M, Palazzolo, M G, Jarolim, P, Creager, M A, O'donoghue, M, Sabatine, M S

“…Abstract Background/Introduction Patients with atherosclerotic vascular disease are at heightened risk of ischemic events, including adverse limb events. The…”
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Heart failure risk assessment using biomarkers in patients with atrial fibrillation: analysis of 32,041 patients from the COMBINE-AF study by Haller, P M, Jarolim, P, Palazzolo, M, Bellavia, A, Harrington, J, Healey, J S, Connolly, S J, Eikelboom, J, Granger, C B, Patel, M R, Ruff, C T, Wallentin, L, Giugliano, R P, Morrow, D A

“…Abstract Introduction Heart failure (HF) is one of the most common comorbidities in patients with AF, resulting in a clinical need for robust risk assessment…”
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Mutations of Conserved Arginines in the Membrane Domain of Erythroid Band 3 Lead to a Decrease in Membrane-Associated Band 3 and to the Phenotype of Hereditary Spherocytosis by Jarolim, Petr, Rubin, Hillard L., Brabec, Vaclav, Chrobak, Ladislav, Zolotarev, Alexander S., Alper, Seth L., Brugnara, Carlo, Wichterle, Hynek, Palek, Jiri

“…To elucidate the molecular basis of band 3 deficiency in a recently defined subset of patients with autosomal dominant hereditary spherocytosis (HS), we…”
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Lipoprotein(a), cardiovascular events, and benefit of P2Y12 inhibition: insights from the PEGASUS-TIMI 54 trial by Patel, S, Morrow, D, Bonaca, M, Palazzolo, M, Jarolim, P, Steg, P G, Bhatt, D, Storey, R, Cohen, M, Braunwald, E, Sabatine, M, O'Donoghue, M

“…Abstract Background Lp(a) plays a causal role in atherogenesis and may exert pro-thrombotic effects by inhibiting fibrinolysis owing to its structural homology…”
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The homozygous state for the band 3 protein mutation in Southeast Asian Ovalocytosis may be lethal [letter] by Liu, SC, Jarolim, P, Rubin, HL, Palek, J, Amato, D, Hassan, K, Zaik, M, Sapak, P

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Heart Failure, Saxagliptin, and Diabetes Mellitus: Observations from the SAVOR-TIMI 53 Randomized Trial by Scirica, B M, Braunwald, E, Raz, I, Cavender, M A, Morrow, D A, Jarolim, P, Udell, J A, Mosenzon, O, Im, K, Umez-Eronini, A A, Pollack, P S, Hirshberg, B, Frederich, R, Lewis, B S, McGuire, D K, Davidson, J, Steg, P G, Bhatt, D L

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Interleukin-6 predicts recovery of systolic function after myocardial infarction by Jenca, D, Jarolim, P, Melenovsky, V, Mrazkova, J, Sramko, M, Zelizko, M, Kotrc, M, Franekova, J, Viczenova, D, Adamkova, V, Kautzner, J, Wohlfahrt, P

“…Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Ministry of Health of the Czech…”
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(789) - Clinical and Humoral Determinants of Congestion-prone Advanced Heart Failure Phenotype by Melenovsky, V., Benes, J., Kotrc, M., Jabor, A., Kautzner, J., Kovar, J., Jarolim, P.

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