Search Results - "Jaramillo, Claudia A. Castro"

In Vitro and In Vivo Evaluation of ABCG2 (BCRP) Inhibitors Derived from Ko143 by Zechner, Melanie, Castro Jaramillo, Claudia A., Zubler, Nadine S., Taddio, Marco F., Mu, Linjing, Altmann, Karl-Heinz, Krämer, Stefanie D.

“…Breast cancer resistance protein (BCRP, ABCG2) is an efflux transporter that plays a crucial role in multidrug resistance to antineoplastic drugs. Ko143, an…”
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In Vivo Imaging of Local Inflammation: Monitoring LPS-Induced CD80/CD86 Upregulation by PET by Taddio, Marco F., Castro Jaramillo, Claudia A., Runge, Peter, Blanc, Alain, Keller, Claudia, Talip, Zeynep, Béhé, Martin, van der Meulen, Nicholas P., Halin, Cornelia, Schibli, Roger, Krämer, Stefanie D.

“…Purpose The co-stimulatory molecules CD80 and CD86 are upregulated on activated antigen-presenting cells (APC). We investigated whether local APC activation,…”
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Synthesis and Structure–Affinity Relationship of Small Molecules for Imaging Human CD80 by Positron Emission Tomography by Taddio, Marco F, Mu, Linjing, Castro Jaramillo, Claudia A, Bollmann, Tanja, Schmid, Dominik M, Muskalla, Lukas P, Gruene, Tim, Chiotellis, Aristeidis, Ametamey, Simon M, Schibli, Roger, Krämer, Stefanie D

“…The costimulatory molecule CD80 is an early marker for immune activation. It is upregulated on activated antigen-presenting cells. We aimed at developing a…”
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Towards imaging the immune state of cancer by PET: Targeting legumain with 11C-labeled P1-Asn peptidomimetics carrying a cyano-warhead by Lustenberger, Severin K., Castro Jaramillo, Claudia A., Bärtschi, Lena A., Williams, Rich, Schibli, Roger, Mu, Linjing, Krämer, Stefanie D.

“…M2-type tumor-associated macrophages (TAM) residing in the tumor microenvironment (TME) have been linked to tumor invasiveness, metastasis and poor prognosis…”
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Toward in vitro-to-in vivo translation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms by Jaramillo, Claudia A Castro, Belli, Sara, Cascais, Anne-Christine, Dudal, Sherri, Edelmann, Martin R, Haak, Markus, Brun, Marie-Elise, Otteneder, Michael B, Ullah, Mohammed, Funk, Christoph, Schuler, Franz, Simon, Silke

“…Monoclonal antibodies (mAbs) are a rapidly growing drug class for which great efforts have been made to optimize certain molecular features to achieve the…”
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Towards imaging the immune state of cancer by PET: Targeting legumain with 11 C-labeled P1-Asn peptidomimetics carrying a cyano-warhead by Lustenberger, Severin K, Castro Jaramillo, Claudia A, Bärtschi, Lena A, Williams, Rich, Schibli, Roger, Mu, Linjing, Krämer, Stefanie D

“…M2-type tumor-associated macrophages (TAM) residing in the tumor microenvironment (TME) have been linked to tumor invasiveness, metastasis and poor prognosis…”
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Toward in vitro-to-in vivo translation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms by Jaramillo, Claudia A. Castro, Belli, Sara, Cascais, Anne-Christine, Dudal, Sherri, Edelmann, Martin R., Haak, Markus, Brun, Marie-Elise, Otteneder, Michael B., Ullah, Mohammed, Funk, Christoph, Schuler, Franz, Simon, Silke

“…Monoclonal antibodies (mAbs) are a rapidly growing drug class for which great efforts have been made to optimize certain molecular features to achieve the…”
Get full text