Search Results - "Jarai, Bader"
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Evaluating UiO-66 Metal–Organic Framework Nanoparticles as Acid-Sensitive Carriers for Pulmonary Drug Delivery Applications
Published in ACS applied materials & interfaces (02-09-2020)“…Developing novel drug carriers for pulmonary delivery is necessary to achieve higher efficacy and consistency for treating pulmonary diseases while limiting…”
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Hydrogel nanoparticle degradation influences the activation and survival of primary macrophages
Published in Journal of materials chemistry. B, Materials for biology and medicine (15-09-2021)“…The effect of nanoparticle (NP) internalization on cell fate has emerged as an important consideration for nanomedicine design, as macrophages and other…”
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Nanoparticle pre-treatment for enhancing the survival and activation of pulmonary macrophage transplant
Published in Drug delivery and translational research (01-07-2023)“…Despite recent clinical successes of chimeric antigen receptor T cell therapies in treating liquid cancers, many lingering challenges stand in the way of…”
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Nanoparticle Internalization Promotes the Survival of Primary Macrophages
Published in Advanced NanoBiomed Research (Online) (01-05-2022)“…Macrophages, a class of tissue resident innate immune cells, are responsible for sequestering foreign objects through the process of phagocytosis, making them…”
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A self-amplifying RNA RSV prefusion-F vaccine elicits potent immunity in pre-exposed and naïve non-human primates
Published in Nature communications (14-11-2024)“…Newly approved subunit and mRNA vaccines for respiratory syncytial virus (RSV) demonstrate effectiveness in preventing severe disease, with protection…”
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Biomaterials-Based Opportunities to Engineer the Pulmonary Host Immune Response in COVID-19
Published in ACS biomaterials science & engineering (10-05-2021)“…The COVID-19 pandemic caused by the global spread of the SARS-CoV-2 virus has led to a staggering number of deaths worldwide and significantly increased burden…”
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Destructive fibrotic teamwork: how both microenvironment stiffness and profibrotic interleukin 13 impair alveolar macrophage phenotype and function
Published in Biomaterials science (27-09-2022)“…The pulmonary fibrotic microenvironment is characterized by increased stiffness of lung tissue and enhanced secretion of profibrotic soluble cues contributing…”
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Macrophage variance: investigating how macrophage origin influences responses to soluble and physical cues with immortalized vs. primary cells in 2D and 3D culture
Published in Frontiers in biomaterials science (22-05-2024)“…Macrophages are phagocytic innate immune cells capable of phenotypical switching in response to the local microenvironment. Studies often use either primary…”
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Engineering Nanoparticle Interactions with Innate Immune Cells to Develop Pulmonary Therapeutic Vehicles and Cell Therapies
Published 01-01-2022“…Macrophages, a class of tissue resident innate immune cells, are responsible for sequestering foreign objects through the process of phagocytosis, making them…”
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Dissertation