Search Results - "Jaquet, Kai"
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Rationale and design of the European multicentre study on Stem Cell therapy in IschEmic Non‐treatable Cardiac diseasE (SCIENCE)
Published in European journal of heart failure (01-08-2019)“…Aims Ischaemic heart failure (IHF) patients have a poor prognosis even with current guideline‐derived therapy. Intramyocardial injections of autologous or…”
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Erythropoietin and VEGF Exhibit Equal Angiogenic Potential
Published in Microvascular research (01-09-2002)“…Erythropoietin (Epo) is a hormone regulating proliferation and differentiation of erythroid cells. The hypothesis that hematopoietic and endothelial cells…”
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Combined delivery approach of bone marrow mononuclear stem cells early and late after myocardial infarction: the MYSTAR prospective, randomized study
Published in Nature clinical practice cardiovascular medicine (01-01-2009)“…Combined intracoronary and intramyocardial administration might improve outcomes for bone-marrow-derived stem cell therapy for acute myocardial infarction. In…”
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Transplantation of Bone Marrow-Derived Stem Cells Improves Myocardial Diastolic Function: Strain Rate Imaging in a Model of Hibernating Myocardium
Published in Journal of the American Society of Echocardiography (01-10-2009)“…Background The aim of this study was to evaluate the cardioprotective effects of bone marrow–derived stem cells on myocardial compliance in a chronic ischemia…”
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Design and rationale for the Myocardial Stem Cell Administration After Acute Myocardial Infarction (MYSTAR) Study: A multicenter, prospective, randomized, single-blind trial comparing early and late intracoronary or combined (percutaneous intramyocardial and intracoronary) administration of nonselected autologous bone marrow cells to patients after acute myocardial infarction
Published in The American heart journal (01-02-2007)“…Background Previous data suggest that bone marrow–derived stem cells (BM-SCs) decrease the infarct size and beneficially affect the postinfarction remodeling…”
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Intramyocardial Transplantation of Bone Marrow-Derived Stem Cells: Ultrasonic Strain Rate Imaging in a Model of Hibernating Myocardium
Published in Journal of cardiac failure (01-12-2008)“…Abstract Background The aim of this study was to evaluate potential cardioprotective effects of bone marrow-derived stem cells in chronic ischemic myocardium…”
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Percutaneous endocardial injection of erythropoietin: Assessment of cardioprotection by electromechanical mapping
Published in European journal of heart failure (01-08-2006)“…Abstract Background: Apart from its well-known stimulation of erythropoiesis, erythropoietin (EPO) exhibits angiogenic and anti-apoptotic effects. These…”
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Potential and clinical utility of stem cells in cardiovascular disease
Published in Stem cells and cloning (26-03-2010)“…The recent identification of bone marrow-derived adult stem cells and other types of stem cells that could improve heart function after transplantation have…”
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Prognostic Impact of Acute Cardiovascular Events in COVID-19 Hospitalized Patients—Results from the CORONA Germany Study
Published in Journal of clinical medicine (02-09-2021)“…Background: Acute myocardial injury (AMJ), assessed by elevated levels of cardiac troponin, is associated with fatal outcome in coronavirus disease 2019…”
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TCT-495 Percutaneous, trans-endocardial injection of bone marrow derived mononuclear cells significantly improves left ventricular ejection fraction in patients following acute myocardial infarction: ALSTER Stem cell trial
Published in Journal of the American College of Cardiology (23-10-2012)“…A subgroup of patients (n=11) included in the previously published LIPSIAbciximab trial also receiving serial CMR measurements was used as a matched control…”
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Long-Term Outcome of Combined (Percutaneous Intramyocardial and Intracoronary) Application of Autologous Bone Marrow Mononuclear Cells Post Myocardial Infarction: The 5-Year MYSTAR Study
Published in PloS one (20-10-2016)“…The long-term (5-year) outcome of early (3-6 weeks after acute myocardial infarction [AMI], BM-MNC Early group) and late (3-4 months after AMI, BM-MNC Late…”
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Percutaneous, transendocardial injection of bone marrow-derived mononuclear cells in heart failure patients following acute ST-elevation myocardial infarction: ALSTER-Stem Cell trial
Published in EuroIntervention (01-10-2012)“…Patients with symptomatic heart failure following acute ST-elevation myocardial infarction (STEMI) received transendocardial application of bone marrow-derived…”
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Stem cell therapy in cardiovascular disorders
Published in Cardiovascular therapeutics (01-10-2010)“…Heart insufficiency remains the leading cause of death despite pharmacological and interventional therapy as well as primary and secondary prevention…”
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Limited immune-modulating activity of porcine mesenchymal stromal cells abolishes their protective efficacy in acute kidney injury
Published in Stem cells and development (01-05-2010)“…We demonstrated previously that administration of mesenchymal stromal cells (MSCs) after renal ischemia/reperfusion injury (IRI) in rats protected renal…”
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Endocardial Electrogram Analysis after Intramyocardial Injection of Mesenchymal Stem Cells in the Chronic Ischemic Myocardium
Published in Pacing and clinical electrophysiology (01-10-2009)“…Background: Cell injection therapies have been introduced for the treatment of patients with coronary heart disease. However, intramyocardial injection of bone…”
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Reduction of myocardial scar size after implantation of mesenchymal stem cells in rats: what is the mechanism?
Published in Stem cells and development (01-06-2005)“…The use of a cellular therapy offers a promising approach for the treatment of heart disease. Besides other precursor cells, bone marrow (BM)-derived stem…”
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Attenuation of cardiac remodelling by endocardial injection of erythropoietin: ultrasonic strain-rate imaging in a model of hibernating myocardium
Published in European heart journal (01-02-2007)“…Aims The aim of this study was to investigate whether erythropoietin (EPO) has cardioprotective effects in a chronic myocardial ischaemia model regarding…”
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Regional Diastolic and Systolic Function by Strain Rate Imaging for the Detection of Intramural Viability during Dobutamine Stress Echocardiography in a Porcine Model of Myocardial Infarction
Published in Echocardiography (Mount Kisco, N.Y.) (01-05-2010)“…The aim of this study was to evaluate diastolic and systolic strain rate measurements for differentiation of transmural/nontransmural infarction during…”
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