Search Results - "Jany, Sylvia"

CD8+ T Cells Responding to the Middle East Respiratory Syndrome Coronavirus Nucleocapsid Protein Delivered by Vaccinia Virus MVA in Mice by Veit, Svenja, Jany, Sylvia, Fux, Robert, Sutter, Gerd, Volz, Asisa

“…Middle East respiratory syndrome coronavirus (MERS-CoV), a novel infectious agent causing severe respiratory disease and death in humans, was first described…”
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Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity by Meyer Zu Natrup, Christian, Tscherne, Alina, Dahlke, Christine, Ciurkiewicz, Malgorzata, Shin, Dai-Lun, Fathi, Anahita, Rohde, Cornelius, Kalodimou, Georgia, Halwe, Sandro, Limpinsel, Leonard, Schwarz, Jan H, Klug, Martha, Esen, Meral, Schneiderhan-Marra, Nicole, Dulovic, Alex, Kupke, Alexandra, Brosinski, Katrin, Clever, Sabrina, Schünemann, Lisa-Marie, Beythien, Georg, Armando, Federico, Mayer, Leonie, Weskamm, Marie L, Jany, Sylvia, Freudenstein, Astrid, Tuchel, Tamara, Baumgärtner, Wolfgang, Kremsner, Peter, Fendel, Rolf, Addo, Marylyn M, Becker, Stephan, Sutter, Gerd, Volz, Asisa

“…The SARS-CoV-2 spike (S) glycoprotein is synthesized as a large precursor protein and must be activated by proteolytic cleavage into S1 and S2. A recombinant…”
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A Soluble Version of Nipah Virus Glycoprotein G Delivered by Vaccinia Virus MVA Activates Specific CD8 and CD4 T Cells in Mice by Kalodimou, Georgia, Veit, Svenja, Jany, Sylvia, Kalinke, Ulrich, Broder, Christopher C, Sutter, Gerd, Volz, Asisa

“…Nipah virus (NiV) is an emerging zoonotic virus that is transmitted by bats to humans and to pigs, causing severe respiratory disease and often fatal…”
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Short- and Long-Interval Prime-Boost Vaccination with the Candidate Vaccines MVA-SARS-2-ST and MVA-SARS-2-S Induces Comparable Humoral and Cell-Mediated Immunity in Mice by Kalodimou, Georgia, Jany, Sylvia, Freudenstein, Astrid, Schwarz, Jan Hendrik, Limpinsel, Leonard, Rohde, Cornelius, Kupke, Alexandra, Becker, Stephan, Volz, Asisa, Tscherne, Alina, Sutter, Gerd

“…The COVID-19 pandemic caused significant human health and economic consequences. Due to the ability of SARS-CoV-2 to spread rapidly and to cause severe disease…”
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E3L and F1L Gene Functions Modulate the Protective Capacity of Modified Vaccinia Virus Ankara Immunization in Murine Model of Human Smallpox by Volz, Asisa, Jany, Sylvia, Freudenstein, Astrid, Lantermann, Markus, Ludwig, Holger, Sutter, Gerd

“…The highly attenuated Modified Vaccinia virus Ankara (MVA) lacks most of the known vaccinia virus (VACV) virulence and immune evasion genes. Today MVA can…”
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Protective CD8+ T Cell Response Induced by Modified Vaccinia Virus Ankara Delivering Ebola Virus Nucleoprotein by Kupke, Alexandra, Volz, Asisa, Dietzel, Erik, Freudenstein, Astrid, Schmidt, Jörg, Shams-Eldin, Hosam, Jany, Sylvia, Sauerhering, Lucie, Krähling, Verena, Gellhorn Serra, Michelle, Herden, Christiane, Eickmann, Markus, Becker, Stephan, Sutter, Gerd

“…The urgent need for vaccines against Ebola virus (EBOV) was underscored by the large outbreak in West Africa (2014-2016). Since then, several promising vaccine…”
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Newly Designed Poxviral Promoters to Improve Immunogenicity and Efficacy of MVA-NP Candidate Vaccines against Lethal Influenza Virus Infection in Mice by Langenmayer, Martin C, Luelf-Averhoff, Anna-Theresa, Marr, Lisa, Jany, Sylvia, Freudenstein, Astrid, Adam-Neumair, Silvia, Tscherne, Alina, Fux, Robert, Rojas, Juan J, Blutke, Andreas, Sutter, Gerd, Volz, Asisa

“…Influenza, a respiratory disease mainly caused by influenza A and B, viruses of the , is still a burden on our society's health and economic system. Influenza…”
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Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein by Volz, Asisa, Kupke, Alexandra, Song, Fei, Jany, Sylvia, Fux, Robert, Shams-Eldin, Hosam, Schmidt, Jörg, Becker, Christin, Eickmann, Markus, Becker, Stephan, Sutter, Gerd

“…Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory disease in humans. We tested a recombinant modified vaccinia virus Ankara…”
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Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination by Tscherne, Alina, Schwarz, Jan Hendrik, Rohde, Cornelius, Kupke, Alexandra, Kalodimou, Georgia, Limpinsel, Leonard, Okba, Nisreen M. A., Bošnjak, Berislav, Sandrock, Inga, Odak, Ivan, Halwe, Sandro, Sauerhering, Lucie, Brosinski, Katrin, Liangliang, Nan, Duell, Elke, Jany, Sylvia, Freudenstein, Astrid, Schmidt, Jörg, Werner, Anke, Serra, Michelle Gellhorn, Klüver, Michael, Guggemos, Wolfgang, Seilmaier, Michael, Wendtner, Clemens-Martin, Förster, Reinhold, Haagmans, Bart L., Becker, Stephan, Sutter, Gerd, Volz, Asisa

“…Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) has emerged as the infectious agent causing the pandemic coronavirus disease 2019…”
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Rapid expansion of CD8+ T cells in wild-type and type I interferon receptor-deficient mice correlates with protection after low-dose emergency immunization with modified vaccinia virus Ankara by Volz, Asisa, Langenmayer, Martin, Jany, Sylvia, Kalinke, Ulrich, Sutter, Gerd

“…Immunization with modified vaccinia virus Ankara (MVA) can rapidly protect mice against lethal ectromelia virus (ECTV) infection, serving as an experimental…”
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Implementation of an Immunoassay Based on the MVA-T7pol-Expression System for Rapid Identification of Immunogenic SARS-CoV-2 Antigens: A Proof-of-Concept Study by Kumar, Satendra, Nan, Liangliang, Kalodimou, Georgia, Jany, Sylvia, Freudenstein, Astrid, Brandmüller, Christine, Müller, Katharina, Girl, Philipp, Ehmann, Rosina, Guggemos, Wolfgang, Seilmaier, Michael, Wendtner, Clemens-Martin, Volz, Asisa, Sutter, Gerd, Fux, Robert, Tscherne, Alina

“…The emergence of hitherto unknown viral pathogens presents a great challenge for researchers to develop effective therapeutics and vaccines within a short time…”
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Rapid Development of Modified Vaccinia Virus Ankara (MVA)-Based Vaccine Candidates Against Marburg Virus Suitable for Clinical Use in Humans by Tscherne, Alina, Kalodimou, Georgia, Kupke, Alexandra, Rohde, Cornelius, Freudenstein, Astrid, Jany, Sylvia, Kumar, Satendra, Sutter, Gerd, Krähling, Verena, Becker, Stephan, Volz, Asisa

“…Background/Objectives: Marburg virus (MARV) is the etiological agent of Marburg Virus Disease (MVD), a rare but severe hemorrhagic fever disease with high case…”
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Immunogenicity and protective efficacy of recombinant Modified Vaccinia virus Ankara candidate vaccines delivering West Nile virus envelope antigens by Volz, Asisa, Lim, Stephanie, Kaserer, Martina, Lülf, Anna, Marr, Lisa, Jany, Sylvia, Deeg, Cornelia A, Pijlman, Gorben P, Koraka, Penelope, Osterhaus, Albert D.M.E, Martina, Byron E, Sutter, Gerd

“…Abstract West Nile virus (WNV) cycles between insects and wild birds, and is transmitted via mosquito vectors to horses and humans, potentially causing severe…”
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