Search Results - "Jantzen, Paul T"
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Microglial Activation and beta -Amyloid Deposit Reduction Caused by a Nitric Oxide-Releasing Nonsteroidal Anti-Inflammatory Drug in Amyloid Precursor Protein Plus Presenilin-1 Transgenic Mice
Published in The Journal of neuroscience (15-03-2002)“…3-4-(2-Fluoro-alpha-methyl-[1,1'-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester (NCX-2216), a nitric oxide (NO)-releasing…”
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Time Course of the Development of Alzheimer-like Pathology in the Doubly Transgenic PS1+APP Mouse
Published in Experimental neurology (01-02-2002)“…Doubly transgenic mice expressing both a mutated amyloid precursor protein and a mutated presenilin-1 protein accumulate Aβ deposits as they age. The early Aβ…”
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Correlation between cognitive deficits and Aβ deposits in transgenic APP+PS1 mice
Published in Neurobiology of aging (01-05-2001)“…Doubly transgenic mAPP+mPS1 mice (15-16 months) had impaired cognitive function in a spatial learning and memory task that combined features of a water maze…”
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Aβ vaccination, but not nitro-NSAID treatment, increases vascular amyloid and microhemorrhage while both reduce parenchymal amyloid
Published in Neuroscience (28-11-2006)“…Vaccination with Aβ 1–42 and treatment with NCX-2216, a novel nitric oxide releasing flurbiprofen derivative, have each been shown separately to reduce amyloid…”
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Increased fibrillar [beta]-amyloid in response to human C1q injections into hippocampus and cortex of APP+PS1 transgenic mice
Published in Neurochemical research (01-01-2003)“…Human C1q when injected directly into hippocampus and cortex of doubly transgenic APP+PS1 mice results in the increase of Congo red-positive fibrillar…”
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Increased Fibrillar beta -Amyloid in Response to Human C1q Injections into Hippocampus and Cortex of APP+PS1 Transgenic Mice
Published in Neurochemical research (01-01-2003)“…Human C1q when injected directly into hippocampus and cortex of doubly transgenic APP+PS1 mice results in the increase of Congo red-positive fibrillar…”
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Increased fibrillar β-amyloid in response to human Clq injections into hippocampus and cortex of APP+PS1 transgenic mice
Published in Neurochemical research (2003)“…Human C1q when injected directly into hippocampus and cortex of doubly transgenic APP+PS1 mice results in the increase of Congo red-positive fibrillar…”
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Time course of the development of Alzheimer-like pathology in the doubly transgenic PSI+APP mouse
Published in Experimental neurology (2002)Get full text
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"Objects Worthy of Notice" Microscopical Anatomy of Selected Plants Collected by The Lewis & Clark Expedition
Published in Microscopy today (01-05-2005)“…Plants that are used for taxonomic research are generally preserved by drying them out while they are being pressed flat for easy storage. This pressed plant…”
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Nucleus basalis lesions in neonate rats induce a selective cortical cholinergic hypofunction and cognitive deficits during adulthood
Published in Experimental brain research (01-01-1992)“…Ibotenic acid was infused into the nucleus basalis magnocellularis (nBM) of 2-day old rats to eliminate immature cholinergic neurons before they develop…”
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