Search Results - "Jansson, P J"

Glucose modulation induces reactive oxygen species and increases P‐glycoprotein‐mediated multidrug resistance to chemotherapeutics by Seebacher, N A, Richardson, D R, Jansson, P J

“…Background and Purpose Cancer cells develop resistance to stress induced by chemotherapy. In tumours, a considerable glucose gradient exists, resulting in…”
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A CMOS time-to-digital converter with better than 10 ps single-shot precision by Jansson, J.-P., Mantyniemi, A., Kostamovaara, J.

“…A high-precision CMOS time-to-digital converter IC has been designed. Time interval measurement is based on a counter and two-level interpolation realized with…”
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Deferasirox (ICL670A) effectively inhibits oesophageal cancer growth in vitro and in vivo by Ford, SJ, Obeidy, P, Lovejoy, DB, Bedford, M, Nichols, L, Chadwick, C, Tucker, O, Lui, GYL, Kalinowski, DS, Jansson, PJ, Iqbal, TH, Alderson, D, Richardson, DR, Tselepis, C

“…Background and Purpose Growing evidence implicates iron in the aetiology of gastrointestinal cancer. Furthermore, studies demonstrate that iron chelators…”
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Synchronization in a Multilevel CMOS Time-to-Digital Converter by Jansson, J.-P., Mantyniemi, A., Kostamovaara, J.

“…Accurate time-to-digital conversion is typically based on determining the positions of the timing signals within the period of an accurate clock with digital…”
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Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease by Lane, D.J.R., Merlot, A.M., Huang, M.L.-H., Bae, D.-H., Jansson, P.J., Sahni, S., Kalinowski, D.S., Richardson, D.R.

“…Iron is a crucial transition metal for virtually all life. Two major destinations of iron within mammalian cells are the cytosolic iron-storage protein,…”
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Regulation of autophagy and apoptosis by Dp44mT-mediated activation of AMPK in pancreatic cancer cells by Krishan, S., Sahni, S., Leck, L.Y.W., Jansson, P.J., Richardson, D.R.

“…Upon activation, the 5′-adenosine monophosphate-activated protein kinase (AMPK) increases catabolism, while inhibiting anabolism. The anti-cancer agent,…”
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Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents by Richardson, D.R., Kalinowski, D.S., Lau, S., Jansson, P.J., Lovejoy, D.B.

“…Cancer contributes to 50% of deaths worldwide and new anti-tumour therapeutics with novel mechanisms of actions are essential to develop. Metabolic inhibitors…”
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During mitosis ZEB1 “switches” from being a chromatin-bound epithelial gene repressor, to become a microtubule-associated protein by Fouani, L., Huang, M.L.H., Cole, L., Jansson, P.J., Kovacevic, Z., Richardson, D.R.

“…Microtubules are polymers of α/β-tubulin, with microtubule organization being regulated by microtubule-associated proteins (MAPs). Herein, we describe a novel…”
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On the effects of the excess bias of the SPAD on the timing accuracy in time interval measurement by Nissinen, J., Nissinen, I., Huikari, J., Jahromi, S., Jansson, J.-P, Kostamovaara, J.

“…The timing accuracy of a single-photon avalanche diode (SPAD) based receiver is analyzed as a function of excess bias voltage. The width of the used optical…”
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A CMOS chip set for accurate pulsed time-of-flight laser range finding by Kurtti, S., Nissinen, J., Jansson, J.-P., Kostamovaara, J.

“…A laser rangefinder device based on pulsed time-of-flight (TOF) distance measurement techniques was constructed and tested. Key blocks of the system are the…”
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Pulsed TOF laser rangefinding with a 2D SPAD-TDC receiver by Jahromi, S., Jansson, J.-P, Kostamovaara, J.

“…A pulsed time-of-flight laser radar based on a high speed/energy optical transmitter and a SPAD-TDC receiver is presented. The transmitter employs a bulk…”
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A Multichannel High-Precision CMOS Time-to-Digital Converter for Laser-Scanner-Based Perception Systems by Jansson, J-P, Koskinen, V., Mantyniemi, A., Kostamovaara, J.

“…A multichannel time-to-digital converter (TDC) implemented with 0.35-μm complementary metal-oxide-semiconductor technology that uses a low-frequency crystal as…”
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Pharmacological targeting of mitochondria in cancer stem cells: An ancient organelle at the crossroad of novel anti-cancer therapies by Skoda, Jan, Borankova, Karolina, Jansson, Patric J., Huang, Michael L.-H., Veselska, Renata, Richardson, Des R.

“…[Display omitted] Mitochondria play vital roles in various cellular processes, ranging from cellular metabolism to signal transduction and cell death…”
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A multi-channel wide range time-to-digital converter with better than 9ps RMS precision for pulsed time-of-flight laser rangefinding by Jansson, J-P, Mantyniemi, A., Kostamovaara, J.

“…A multi-channel time-to-digital converter has been realized in 0.35μm CMOS. The 7-channel converter is based on a multiplying delay-locked loop acting as a…”
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Oxidative decomposition of vitamin C in drinking water by Jansson, Patric J, Jung, Hye R, Lindqvist, Christer, Nordström, Tommy

“…We have previously shown that vitamin C (ascorbic acid) can initiate hydroxyl radical formation in copper contaminated household drinking water. In the present…”
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Iron prevents ascorbic acid (vitamin C) induced hydrogen peroxide accumulation in copper contaminated drinking water by Jansson, Patric J, Lindqvist, Christer, Nordström, Tommy

“…Ascorbic acid (vitamin C) induced hydrogen peroxide (H(2)O(2)) formation was measured in household drinking water and metal supplemented Milli-Q water by using…”
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Effects of iron on Vitamin C/copper-induced hydroxyl radical generation in bicarbonate-rich water by Jansson, Patric J, Del Castillo, Urko, Lindqvist, Christer, Nordström, Tommy

“…The aim of this study was to evaluate whether iron, like copper, could support Vitamin C mediated hydroxyl radical formation in bicarbonate-rich water. By…”
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Measurement of ascorbic acid (vitamin C) induced hydroxyl radical generation in household drinking water by Asplund, Klara U M, Jansson, Patric J, Lindqvist, Christer, Nordström, Tommy

“…Ascorbic acid (vitamin C) induced hydroxyl radical formation was measured in household drinking water samples using the hydroxyl radical sensitive probe…”
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Vitamin C (ascorbic acid) induced hydroxyl radical formation in copper contaminated household drinking water: role of bicarbonate concentration by Jansson, Patric J, Asplund, Klara U M, Mäkelä, Johanna C, Lindqvist, Christer, Nordström, Tommy

“…We have previously shown that Vitamin C (ascorbic acid) can trigger hydroxyl radical formation in copper contaminated household drinking water. We report here…”
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