Search Results - "Jansson, O"

Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance by Matthews, V. B, Allen, T. L, Risis, S, Chan, M. H. S, Henstridge, D. C, Watson, N, Zaffino, L. A, Babb, J. R, Boon, J, Meikle, P. J, Jowett, J. B, Watt, M. J, Jansson, J.-O, Bruce, C. R, Febbraio, M. A

“…Aims/hypothesis The role of IL-6 in the development of obesity and hepatic insulin resistance is unclear and still the subject of controversy. We aimed to…”
Get full text

Ritonavir-boosted darunavir combined with raltegravir or tenofovir–emtricitabine in antiretroviral-naive adults infected with HIV-1: 96 week results from the NEAT001/ANRS143 randomised non-inferiority trial by Raffi, François, Prof, Babiker, Abdel G, Prof, Richert, Laura, PhD, Molina, Jean-Michel, Prof, George, Elizabeth C, MSc, Antinori, Andrea, MD, Arribas, Jose R, MD, Grarup, Jesper, DVM, Hudson, Fleur, BA, Schwimmer, Christine, PhD, Saillard, Juliette, MSc, Wallet, Cédrick, MSc, Jansson, Per O, RN, Allavena, Clotilde, MD, Van Leeuwen, Remko, PhD, Delfraissy, Jean-François, Prof, Vella, Stefano, MD, Chêne, Geneviève, Prof, Pozniak, Anton, MD

“…Summary Background Standard first-line antiretroviral therapy for HIV-1 infection includes two nucleoside or nucleotide reverse transcriptase inhibitors…”
Get full text

Inter-relation between Interleukin (IL)-1, IL-6 and Body Fat Regulating Circuits of the Hypothalamic Arcuate Nucleus by Schéle, E., Benrick, A., Grahnemo, L., Egecioglu, E., Anesten, F., Pálsdóttir, V., Jansson, J.-O.

“…Interleukin (IL)‐1 and IL‐6 are immune modulating cytokines that also affect metabolic function because both IL‐1 receptor I deficient (IL‐1RI−/−) and IL‐6…”
Get full text

Exposure to candesartan during the first trimester of pregnancy in type 1 diabetes: experience from the placebo-controlled diabetic retinopathy candesartan trials by Porta, M., Hainer, J. W., Jansson, S.-O., Malm, A., Bilous, R., Chaturvedi, N., Fuller, J. H., Klein, R., Orchard, T., Parving, H.-H., Sjølie, A.-K.

“…Aims/hypothesis The teratogenic consequences of angiotensin-converting enzyme inhibitors angiotensin receptor blockers (ARBs) during the second and third…”
Get full text

Interleukin-6 Gene Knockout Influences Energy Balance Regulating Peptides in the Hypothalamic Paraventricular and Supraoptic Nuclei by Benrick, A., Schéle, E., Pinnock, S. B., Wernstedt-Asterholm, I., Dickson, S. L., Karlsson-Lindahl, L., Jansson, J.-O.

“…Interleukin (IL)‐6 is a pro‐inflammatory cytokine that also affects metabolic function because IL‐6 depleted (IL‐6−/−) mice develop late‐onset obesity. IL‐6…”
Get full text

Functional interleukin‐6 receptor‐α is located in tanycytes at the base of the third ventricle by Anesten, F., Santos, C., Gidestrand, E., Schéle, E., Pálsdóttir, V., Swedung‐Wettervik, T., Meister, B., Patrycja Skibicka, K., Jansson, J.‐O.

“…Interleukin (IL)‐6−/− mice develop mature onset obesity, whereas i.c.v. injection of IL‐6 decreases obesity in rodents. Moreover, levels of IL‐6 in…”
Get full text

Female Mice Lacking Estrogen Receptor-α in Hypothalamic Proopiomelanocortin (POMC) Neurons Display Enhanced Estrogenic Response on Cortical Bone Mass by Farman, H. H, Windahl, S. H, Westberg, L, Isaksson, H, Egecioglu, E, Schele, E, Ryberg, H, Jansson, J. O, Tuukkanen, J, Koskela, A, Xie, S. K, Hahner, L, Zehr, J, Clegg, D. J, Lagerquist, M. K, Ohlsson, C

“…Estrogens are important regulators of bone mass and their effects are mainly mediated via estrogen receptor (ER)α. Central ERα exerts an inhibitory role on…”
Get full text

Interleukin-6 Receptor α is Co-localised with Melanin-Concentrating Hormone in Human and Mouse Hypothalamus by Schéle, E., Fekete, C., Egri, P., Füzesi, T., Palkovits, M., Keller, É., Liposits, Z., Gereben, B., Karlsson-Lindahl, L., Shao, R., Jansson, J.-O.

“…Interleukin (IL)‐6 deficient mice develop mature‐onset obesity. Furthermore, i.c.v. administration of IL‐6 increases energy expenditure, suggesting that IL‐6…”
Get full text

Mortality and cardiovascular disease outcomes among 740 patients with new-onset Type 2 diabetes detected by screening or clinically diagnosed in general practice by Jansson, S. P. O., Andersson, D. K. G., Svärdsudd, K.

“…Aim Screening for Type 2 diabetes among people at high risk is recommended by many organizations. The aim of this study was to analyse all‐cause mortality and…”
Get full text

Specific Binding of Proinsulin C-Peptide to Human Cell Membranes by Rigler, R., Pramanik, A., Jonasson, P., Kratz, G., Jansson, O. T., P.-Å. Nygren, Ståhl, S., Ekberg, K., B.-L. Johansson, Uhlén, S., Uhlén, M., Jörnvall, H., Wahren, J.

“…Recent reports have demonstrated beneficial effects of proinsulin C-peptide in the diabetic state, including improvements of kidney and nerve function. To…”
Get full text

Endocrine, liver-derived IGF-I is of importance for spatial learning and memory in old mice by Svensson, J, Diez, M, Engel, J, Wass, C, Tivesten, Å, Jansson, J-O, Isaksson, O, Archer, T, Hökfelt, T, Ohlsson, C

“…IGF-I is a neuroprotective hormone, and neurodegenerative disorders, including Alzheimer’s disease, have been associated with decreased serum IGF-I…”
Get full text

Effects of fasting blood glucose levels and blood pressure and treatment of diabetes and hypertension on the incidence of cardiovascular disease: a study of 740 patients with incident Type 2 diabetes with up to 30 years' follow-up by Jansson, S. P. O., Svärdsudd, K., Andersson, D. K. G.

“…Aims To analyse the effects of hyperglycaemia and hypertension and treatment of diabetes and hypertension on cardiovascular disease incidence in patients with…”
Get full text

Ghrelin treatment reverses the reduction in weight gain and body fat in gastrectomised mice by Dornonville de la Cour, C, Lindqvist, A, Egecioglu, E, Tung, Y C L, Surve, V, Ohlsson, C, Jansson, J-O, Erlanson-Albertsson, C, Dickson, S L, Håkanson, R

“…Background and aims: The gastric hormone ghrelin has been reported to stimulate food intake, increase weight gain, and cause obesity but its precise…”
Get full text

Prevalence and incidence rate of diabetes mellitus in a Swedish community during 30 years of follow-up by Jansson, S. P. O, Andersson, D. K. G, Svärdsudd, K

“…Aims/hypothesis Increasing diabetes prevalence has been reported in most European countries in the last 20 years. In this study we report on the development of…”
Get full text

A common polymorphism in the interleukin-6 gene promoter is associated with overweight by WERNSTEDT, I, ERIKSSON, A-L, BERNDTSSON, A, HOFFSTEDT, J, SKRTIC, S, HEDNER, T, HULTEN, L. M, WIKLUND, O, OHLSSON, C, JANSSON, J-O

“…Human body fat mass is to a large extent genetically determined, but little is known about the susceptibility genes for common obesity. Interleukin-6 (IL-6)…”
Get full text

Prevalence and incidence of diabetes mellitus: a nationwide population-based pharmaco-epidemiological study in Sweden by Jansson, S. P. O., Fall, K., Brus, O., Magnuson, A., Wändell, P., Östgren, C. J., Rolandsson, O.

“…Aim To investigate the changes in prevalence and incidence of pharmacologically and non‐pharmacologically treated diabetes in Sweden during 2005 to 2013…”
Get full text

Nanoscale Affinity Chip Interface for Coupling Inhibition SPR Immunosensor Screening with Nano-LC TOF MS by Marchesini, G. R, Buijs, J, Haasnoot, W, Hooijerink, D, Jansson, O, Nielen, M. W. F

“…The on-line nanoscale coupling of a surface plasmon resonance (SPR)-based inhibition biosensor immunoassay (iBIA) for the screening of low molecular weight…”
Get full text

Mortality in first- and second-generation immigrants to Sweden diagnosed with type 2 diabetes: a 10 year nationwide cohort study by Bennet, Louise, Udumyan, Ruzan, Östgren, Carl Johan, Rolandsson, Olov, Jansson, Stefan P. O., Wändell, Per

“…Aims/hypothesis Non-Western immigrants to Europe are at high risk for type 2 diabetes. In this nationwide study including incident cases of type 2 diabetes,…”
Get full text

Effects of fasting blood glucose, diabetes treatment, blood pressure and anti-hypertension treatment on cardiovascular disease incidence: a 30-year follow-up study of 740 incident patients with Type 2 diabetes by JANSSON, S. P. O, ANDERSSON, D. K. G, SVÄRDSUDD, K

“…To analyse the effects of hyperglycaemia and blood pressure, diabetes and anti-hypertension treatment on total and various types of cardiovascular disease…”
Get full text

A variant near the interleukin-6 gene is associated with fat mass in Caucasian men by Andersson, N, Strandberg, L, Nilsson, S, Adamovic, S, Karlsson, M K, Ljunggren, Ö, Mellström, D, Lane, N E, Zmuda, J M, Nielsen, C, Orwoll, E, Lorentzon, M, Ohlsson, C, Jansson, J-O

“…Context: Regulation of fat mass appears to be associated with immune functions. Studies of knockout mice show that endogenous interleukin (IL)-6 can suppress…”
Get full text