Search Results - "Janssen, Samuel"

Screening a combinatorial peptide library to develop a human glandular kallikrein 2–activated prodrug as targeted therapy for prostate cancer by Janssen, Samuel, Jakobsen, Carsten M, Rosen, D Marc, Ricklis, Rebecca M, Reineke, Ulrich, Christensen, Soeren B, Lilja, Hans, Denmeade, Samuel R

“…Objective: Prostate cancer cells secrete the unique protease human glandular kallikrein 2 (hK2) that represents a target for proteolytic activation of…”
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Prostate-Specific Antigen-Activated Thapsigargin Prodrug as Targeted Therapy for Prostate Cancer by Denmeade, Samuel R., Jakobsen, Carsten M., Janssen, Samuel, Khan, Saeed R., Garrett, Elizabeth S., Lilja, Hans, Christensen, S. Brogger, Isaacs, John T.

“…Background: Standard anti-proliferative chemotherapy is relatively ineffective against slowly proliferating androgen-independent prostate cancer cells within…”
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Specific targeting of insect and vertebrate telomeres with pyrrole and imidazole polyamides by Maeshima, Kazuhiro, Janssen, Samuel, Laemmli, Ulrich K.

“…DNA minor groove‐binding compounds (polyamides) that target insect and vertebrate telomeric repeats with high specificity were synthesized. Base pair…”
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Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug by Janssen, Samuel, Rosen, D. Marc, Ricklis, Rebecca M., Dionne, Craig A., Lilja, Hans, Christensen, Soeren B., Isaacs, John T., Denmeade, Samuel R.

“…BACKGROUND Prostate cancer cells secrete unique proteases such as prostate‐specific antigen (PSA) and human glandular kallikrein 2 (hK2) that represent targets…”
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A combinatorial approach to the selective capture of circulating malignant epithelial cells by peptide ligands by Aggarwal, Saurabh, Janssen, Samuel, Wadkins, Randy M., Harden, James L., Denmeade, Samuel R.

“…Early detection is critical in the administration of definitive and curative therapy of cancer. However, current detection methods are ineffective at…”
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