Search Results - "Janssen, Laura G.M."

Higher Plasma Sclerostin and Lower Wnt Signaling Gene Expression in White Adipose Tissue of Prediabetic South Asian Men Compared with White Caucasian Men by Janssen, Laura G M, Van Dam, Andrea D, Hanssen, Mark J W, Kooijman, Sander, Nahon, Kimberly J, Reinders, Hanneke, Jazet, Ingrid M, Van Marken Lichtenbelt, Wouter D, Rensen, Patrick C N, Appelman-Dijkstra, Natasha M, Boon, Mariëtte R

“…South Asians generally have an unfavourable metabolic phenotype compared with white Caucasians, including central obesity and insulin resistance. The Wnt…”
Get full text

Higher insulin and glucagon-like peptide-1 (GLP-1) levels in healthy, young South Asians as compared to Caucasians during an oral glucose tolerance test by Sleddering, Maria A, Bakker, Leontine E.H, Janssen, Laura G.M, Meinders, A. Edo, Jazet, Ingrid M

“…Abstract Objective Higher insulin levels during an oral glucose test (OGTT) have been shown in South Asians. We aimed to investigate if this increased insulin…”
Get full text

Twelve weeks of exenatide treatment increases [18F]fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy expenditure in nondiabetic males by Janssen, Laura G.M., Nahon, Kimberly J., Bracké, Katrien F.M., van den Broek, Dennis, Smit, Renée, Sardjoe Mishre, Aashley S.D., Koorneef, Lisa L., Martinez-Tellez, Borja, Burakiewicz, Jedrzej, Kan, Hermien E., van Velden, Floris H.P., Pereira Arias-Bouda, Lenka M., de Geus-Oei, Lioe-Fee, Berbée, Jimmy F.P., Jazet, Ingrid M., Boon, Mariëtte R., Rensen, Patrick C.N.

“…Brown adipose tissue (BAT) improves energy metabolism by combusting glucose and lipids into heat. Agonism of the glucagon-like peptide-1 receptor (GLP-1R)…”
Get full text

The effect of mirabegron on energy expenditure and brown adipose tissue in healthy lean South Asian and Europid men by Nahon, Kimberly J., Janssen, Laura G. M., Sardjoe Mishre, Aashley S. D., Bilsen, Manu P., Eijk, Jari A., Botani, Kani, Overduin, Lisanne A., Ruiz, Jonatan R., Burakiewicz, Jedrzej, Dzyubachyk, Oleh, Webb, Andrew G., Kan, Hermien E., Berbée, Jimmy F. P., Klinken, Jan‐Bert, Dijk, Ko Willems, Weeghel, Michel, Vaz, Frédéric M., Coskun, Tamer, Jazet, Ingrid M., Kooijman, Sander, Martinez‐Tellez, Borja, Boon, Mariëtte R., Rensen, Patrick C. N.

“…Aim To compare the effects of cold exposure and the β3‐adrenergic receptor agonist mirabegron on plasma lipids, energy expenditure and brown adipose tissue…”
Get full text

Comprehensive (apo)lipoprotein profiling in patients with genetic hypertriglyceridemia using LC-MS and NMR spectroscopy by Straat, Maaike E., Martinez-Tellez, Borja, Nahon, Kimberly J., Janssen, Laura G.M., Verhoeven, Aswin, van der Zee, Leonie, Mulder, Monique T., Kooijman, Sander, Boon, Mariëtte R., van Lennep, Jeanine E. Roeters, Cobbaert, Christa M., Giera, Martin, Rensen, Patrick C.N.

“…•Mutations in LPL or its regulators can cause genetic hypertriglyceridemia (HTG)•Multiplex LC-MS and NMR spectroscopy provide detailed (apo)lipoprotein…”
Get full text

Cold exposure induces dynamic changes in circulating triacylglycerol species, which is dependent on intracellular lipolysis: A randomized cross-over trial by Straat, Maaike E., Jurado-Fasoli, Lucas, Ying, Zhixiong, Nahon, Kimberly J., Janssen, Laura G.M., Boon, Mariëtte R., Grabner, Gernot F., Kooijman, Sander, Zimmermann, Robert, Giera, Martin, Rensen, Patrick C.N., Martinez-Tellez, Borja

“…The application of cold exposure has emerged as an approach to enhance whole-body lipid catabolism. The global effect of cold exposure on the lipidome in…”
Get full text

Cold exposure induces dynamic changes in circulating triacylglycerol species, which is dependent on intracellular lipolysis: A randomized cross-over trialResearch in context by Maaike E. Straat, Lucas Jurado-Fasoli, Zhixiong Ying, Kimberly J. Nahon, Laura G.M. Janssen, Mariëtte R. Boon, Gernot F. Grabner, Sander Kooijman, Robert Zimmermann, Martin Giera, Patrick C.N. Rensen, Borja Martinez-Tellez

“…Background: The application of cold exposure has emerged as an approach to enhance whole-body lipid catabolism. The global effect of cold exposure on the…”
Get full text

The effect of cold exposure on circulating transcript levels of immune genes in Dutch South Asian and Dutch Europid men by Straat, Maaike E., Martinez-Tellez, Borja, Janssen, Laura G.M., van Veen, Suzanne, van Eenige, Robin, Kharagjitsing, Aan V., van den Berg, Sjoerd A.A., de Rijke, Yolanda B., Haks, Mariëlle C., Rensen, Patrick C.N., Boon, Mariëtte R.

“…Although cold exposure is commonly believed to be causally related to acute viral respiratory infections, its effect on the immune system is largely…”
Get full text

LDL aggregation susceptibility is higher in healthy South Asian compared with white Caucasian men by Ruuth, Maija, Janssen, Laura G.M., Äikäs, Lauri, Tigistu-Sahle, Feven, Nahon, Kimberly J., Ritvos, Olli, Ruhanen, Hanna, Käkelä, Reijo, Boon, Mariëtte R., Öörni, Katariina, Rensen, Patrick C.N.

“…South Asians are more prone to develop atherosclerotic cardiovascular disease (ASCVD) compared with white Caucasians, which is not fully explained by classical…”
Get full text

Insulin-like growth factor 1 receptor expression and IGF1R 3129G > T polymorphism are associated with response to neoadjuvant chemotherapy in breast cancer patients: results from the NEOZOTAC trial (BOOG 2010-01) by de Groot, Stefanie, Charehbili, Ayoub, van Laarhoven, Hanneke W M, Mooyaart, Antien L, Dekker-Ensink, N Geeske, van de Ven, Saskia, Janssen, Laura G M, Swen, Jesse J, Smit, Vincent T H B M, Heijns, Joan B, Kessels, Lonneke W, van der Straaten, Tahar, Böhringer, Stefan, Gelderblom, Hans, van der Hoeven, Jacobus J M, Guchelaar, Henk-Jan, Pijl, Hanno, Kroep, Judith R

“…The insulin-like growth factor 1 (IGF-1) pathway is involved in cell growth and proliferation and is associated with tumorigenesis and therapy resistance. This…”
Get full text

Human Brown Adipose Tissue Estimated With Magnetic Resonance Imaging Undergoes Changes in Composition After Cold Exposure: An in vivo MRI Study in Healthy Volunteers by Abreu-Vieira, Gustavo, Sardjoe Mishre, Aashley S D, Burakiewicz, Jedrzej, Janssen, Laura G M, Nahon, Kimberly J, van der Eijk, Jari A, Riem, Titia T, Boon, Mariëtte R, Dzyubachyk, Oleh, Webb, Andrew G, Rensen, Patrick C N, Kan, Hermien E

“…Magnetic resonance imaging (MRI) is increasingly being used to evaluate brown adipose tissue (BAT) function. Reports on the extent and direction of…”
Get full text

Short-Term Cooling Increases Plasma ANGPTL3 and ANGPTL8 in Young Healthy Lean Men but Not in Middle-Aged Men with Overweight and Prediabetes by Janssen, Laura G M, Jauhiainen, Matti, Olkkonen, Vesa M, Haridas, P A Nidhina, Nahon, Kimberly J, Rensen, Patrick C N, Boon, Mariëtte R

“…Angiopoietin-like proteins (ANGPTLs) regulate triglyceride (TG)-rich lipoprotein distribution via inhibiting TG hydrolysis by lipoprotein lipase in metabolic…”
Get full text