Search Results - "Janssen, Lambert H. M"

Convergence Properties of Free Energy Calculations: .alpha.-Cyclodextrin Complexes as a Case Study by Mark, Alan E, van Helden, Steven P, Smith, Paul E, Janssen, Lambert H. M, van Gunsteren, Wilfred F

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The role of protein charge in protein-lipid interactions. pH-Dependent changes of the electrophoretic mobility of liposomes through adsorption of water-soluble, globular proteins by Bergers, Joep J, Vingerhoeds, Monique H, van Bloois, Louis, Herron, James N, Janssen, Lambert H. M, Fischer, Marcel J. E, Crommelin, Daan J. A

“…The role of electrostatics in the adsorption process of proteins to preformed negatively-charged (phosphatidylcholine/phosphatidylglycerol) and neutral…”
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Mitosene−DNA Adducts. Characterization of Two Major DNA Monoadducts Formed by 1,10-Bis(acetoxy)-7-methoxymitosene upon Reductive Activation by Maliepaard, Marc, de Mol, Nico J, Tomasz, Maria, Gargiulo, Dario, Janssen, Lambert H. M, van Duynhoven, John P. M, van Velzen, Ewoud J. J, Verboom, Willem, Reinhoudt, David N

“…Reductive activation of racemic 1,10-bis(acetoxy)-7-methoxymitosene WV15 in the presence of DNA, followed by enzymatic digestion and HPLC analysis, revealed…”
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Reductive activation of potential antitumor mitosene compounds by Maliepaard, Marc, de Mol, Nico J, Janssen, Lambert H. M, Hoogvliet, Joop C, van der Neut, Wouter, Verboom, Willem, Reinhoudt, David N

“…The reductive activation of mitosene compounds was studied with cyclic voltammetry and HPLC analysis. Reduction of mitosenes, possessing good leaving groups at…”
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In Vivo Activity and Hydrophobicity of Cytostatic Aziridinyl Quinones by Moret, Ed E, de Boer, Mark, Hilbers, Hans W, Tollenaere, Jan P, Janssen, Lambert H. M, Holthuis, Joost J. M, Driebergen, Reinoud J, Verboom, Willem, Reinhoudt, David N

“…For a series of 3,6-disubstituted bisaziridinylbenzoquinones the in vivo and in vitro activities against murine tumors, as well as the in vivo toxicity, are…”
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Influence of sodium ion-pair formation on transport kinetics of warfarin through octanol-impregnated membranes by Cools, A A, Janssen, L H

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The uptake of the trypanocidal drug suramin in combination with low-density lipoproteins by Trypanosoma brucei and its possible mode of action by Vansterkenburg, E L, Coppens, I, Wilting, J, Bos, O J, Fischer, M J, Janssen, L H, Opperdoes, F R

“…In plasma, a significant part of suramin circulates in tight association with low-density lipoproteins (LDL). At therapeutically obtainable concentrations (100…”
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Modeling and conformation analysis of beta-cyclodextrin complexes by Kostense, A S, van Helden, S P, Janssen, L H

“…A series of beta-cyclodextrin complexes containing various guest molecules was studied using computer-aided molecular modeling and conformation analysis…”
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Experimental observation of ionic forces in drug-protein interactions as illustrated by the binding of sulfaethidole by human serum albumin by Janssen, L H, Van Wilgenburg, M T

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The Interaction of 2,3-Diphosphoglycerate with Human Hemoglobin by de Bruin, Simon H., Janssen, Lambert H.M.

“…A model is presented which is able to describe satisfactorily the increase of the alkaline and acid Bohr effect due to the binding by human hemoglobin of…”
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Conformational Changes and Ligand Dissociation Kinetics following Rapid Reduction of Human Aquomethemoglobin and Horse Aquometmyoglobin by Hydrated Electrons by Wilting, Jaap, Raap, Adriaan, Braams, Reinier, De Bruin, Simon H., Rollema, Harry S., Janssen, Lambert H.M.

“…By pulse radiolysis and fast spectrometry the reduction of methemoglobin and metmyoglobin by hydrated electrons has been followed by measuring the spectral…”
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Estimation of free energy change associated with conformational transition of proteins showing cooperative binding properties by Janssen, L H, Perrin, J H

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Titration behavior of histidines in human, horse, and bovine hemoglobins by Janssen, L.H.M, De Bruin, S.H, Van Os, G.A.J

“…The titration curves of the human hemoglobins A 2 and F, the slow and fast components of horse hemoglobin, and bovine hemoglobin B have been analyzed, mainly…”
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Hydrogen‐Ion‐Titration Studies of Pancreatic Phospholipase A and Its Zymogen by Janssen, Lambert H. M., Bruin, Simon H., Haas, Gerard H.

“…The titration curves of porcine pancreatic phospholipase A an its zymogen were measured in the pH region 2.0 to 9.5 at 25°C. In the pH region 2 to 6 the…”
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Allosteric models for the interaction of 2,3-diphosphoglyceric acid with hemoglobin by Janssen, L H, de Bruin, S H

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Quaternary‐Structure‐Dependent Proton Dissociation of Tyrosines, Lysines and Cysteines in Human Hemoglobin by Janssen, Lambert H. M., Willekens, Frans L. A., Bruin, Simon H., Os, Gerard A. J.

“…The titration behaviour of tyrosines, lysines and the –SH groups of the β‐93 cysteines in human carboxy and deoxyhemoglobin was studied in the pH region 9 to…”
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