Search Results - "Janss, Luc L."
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Optimizing Training Population Size and Genotyping Strategy for Genomic Prediction Using Association Study Results and Pedigree Information. A Case of Study in Advanced Wheat Breeding Lines
Published in PloS one (12-01-2017)“…Wheat breeding programs generate a large amount of variation which cannot be completely explored because of limited phenotyping throughput. Genomic prediction…”
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A comparison of multivariate genome-wide association methods
Published in PloS one (01-04-2014)“…Joint association analysis of multiple traits in a genome-wide association study (GWAS), i.e. a multivariate GWAS, offers several advantages over analyzing…”
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Genome-wide association and biological pathway analysis for milk-fat composition in Danish Holstein and Danish Jersey cattle
Published in BMC genomics (15-12-2014)“…The milk fat profile of the Danish Holstein (DH) and Danish Jersey (DJ) show clear differences. Identification of the genomic regions, genes and biological…”
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Genome-Wide Association Studies and Comparison of Models and Cross-Validation Strategies for Genomic Prediction of Quality Traits in Advanced Winter Wheat Breeding Lines
Published in Frontiers in plant science (02-02-2018)“…The aim of the this study was to identify SNP markers associated with five important wheat quality traits (grain protein content, Zeleny sedimentation, test…”
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Genomic Selection in Cereal Breeding
Published in Agronomy (Basel) (19-02-2019)“…Genomic Selection (GS) is a method in plant breeding to predict the genetic value of untested lines based on genome-wide marker data. The method has been…”
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Association studies using family pools of outcrossing crops based on allele-frequency estimates from DNA sequencing
Published in Theoretical and applied genetics (01-06-2014)“…KEY MESSAGE : We propose a method in which GBS data can be conveniently analyzed without calling genotypes. F2 families are frequently used in breeding of…”
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Effect of genomic selection and genotyping strategy on estimation of variance components in animal models using different relationship matrices
Published in Genetics selection evolution (Paris) (11-06-2020)“…Abstract Background The traditional way to estimate variance components (VC) is based on the animal model using a pedigree-based relationship matrix ( A )…”
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Heterogeneity of Genetic Modifiers Ensures Normal Cardiac Development
Published in Circulation (New York, N.Y.) (23-03-2010)“…Mutations of the transcription factor Nkx2-5 cause pleiotropic heart defects with incomplete penetrance. This variability suggests that additional factors can…”
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From genetical genomics to systems genetics: potential applications in quantitative genomics and animal breeding
Published in Mammalian genome (01-06-2006)“…This article reviews methods of integration of transcriptomics (and equally proteomics and metabolomics), genetics, and genomics in the form of systems…”
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Genomic prediction and GWAS of yield, quality and disease-related traits in spring barley and winter wheat
Published in Scientific reports (25-02-2020)“…Genome-wide association study (GWAS) and genomic prediction (GP) are extensively employed to accelerate genetic gain and identify QTL in plant breeding. In…”
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Evidence of a Major Gene From Bayesian Segregation Analyses of Liability to Osteochondral Diseases in Pigs
Published in Genetics (Austin) (01-11-2005)“…Bayesian segregation analyses were used to investigate the mode of inheritance of osteochondral lesions (osteochondrosis, OC) in pigs. Data consisted of 1163…”
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The giant diploid faba genome unlocks variation in a global protein crop
Published in Nature (London) (23-03-2023)“…Increasing the proportion of locally produced plant protein in currently meat-rich diets could substantially reduce greenhouse gas emissions and loss of…”
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Population and systems genetics analyses of cortisol in pigs divergently selected for stress
Published in Physiological genomics (14-03-2007)“…1 Institute of Animal Sciences, Swiss Federal Institute of Technology, ETH-Zentrum, Zurich, Switzerland 2 Commonwealth Scientific and Industrial Research…”
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Detection of quantitative trait loci for backfat thickness and intramuscular fat content in pigs (Sus scrofa)
Published in Genetics (Austin) (01-08-1999)“…In an experimental cross between Meishan and Dutch Large White and Landrace lines, 619 F(2) animals and their parents were typed for molecular markers covering…”
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Estimating genomic heritabilities at the level of family-pool samples of perennial ryegrass using genotyping-by-sequencing
Published in Theoretical and applied genetics (01-01-2016)“…KEYMESSAGE : By using the genotyping-by-sequencing method, it is feasible to characterize genomic relationships directly at the level of family pools and to…”
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Biochemical pathways analysis of microarray results: regulation of myogenesis in pigs
Published in BMC developmental biology (13-06-2007)“…Combining microarray results and biological pathway information will add insight into biological processes. Pathway information is widely available in…”
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Author Correction: Genomic prediction and GWAS of yield, quality and disease-related traits in spring barley and winter wheat
Published in Scientific reports (13-05-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Exploring causal networks of bovine milk fatty acids in a multivariate mixed model context
Published in Genetics selection evolution (Paris) (17-01-2014)“…Knowledge regarding causal relationships among traits is important to understand complex biological systems. Structural equation models (SEM) can be used to…”
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Efficiency of population structures for mapping of Mendelian and imprinted quantitative trait loci in outbred pigs using variance component methods
Published in Genetics selection evolution (Paris) (15-11-2005)“…In a simulation study different designs for a pure line pig population were compared for efficiency of mapping QTL using the variance component method…”
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Efficiency of genomic selection using Bayesian multi-marker models for traits selected to reflect a wide range of heritabilities and frequencies of detected quantitative traits loci in mice
Published in BMC genetics (31-05-2012)“…Genomic selection uses dense single nucleotide polymorphisms (SNP) markers to predict breeding values, as compared to conventional evaluations which estimate…”
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