Search Results - "Jansook, Phatsawee"

Cyclodextrins: structure, physicochemical properties and pharmaceutical applications by Jansook, Phatsawee, Ogawa, Noriko, Loftsson, Thorsteinn

“…[Display omitted] Since their discovery over 100 years ago cyclodextrins (CDs) have been the subject of numerous scientific publications. In 2016 alone CDs…”
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Solubility of Cyclodextrins and Drug/Cyclodextrin Complexes by Saokham, Phennapha, Muankaew, Chutimon, Jansook, Phatsawee, Loftsson, Thorsteinn

“…Cyclodextrins (CDs), a group of oligosaccharides formed by glucose units bound together in a ring, show a promising ability to form complexes with drug…”
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Anomalous Properties of Cyclodextrins and Their Complexes in Aqueous Solutions by Loftsson, Thorsteinn, Sigurdsson, Hákon Hrafn, Jansook, Phatsawee

“…Cyclodextrins (CDs) are cyclic oligosaccharides that emerged as industrial excipients in the early 1970s and are currently found in at least 130 marketed…”
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Aqueous Prostaglandin Eye Drop Formulations by Jansook, Phatsawee, Loftsson, Thorsteinn

“…Glaucoma is one of the leading causes of irreversible blindness worldwide. It is characterized by progressive optic neuropathy in association with damage to…”
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CDs as solubilizers: Effects of excipients and competing drugs by Jansook, Phatsawee, Loftsson, Thorsteinn

“…In recent years cyclodextrins (CDs) have been acknowledged by the pharmaceutical industry as very useful enabling excipients for solubilization and…”
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Development of Fenofibrate/Randomly Methylated β-Cyclodextrin-Loaded Eudragit® RL 100 Nanoparticles for Ocular Delivery by Khin, Soe Yadanar, Soe, Hay Man Saung Hnin, Chansriniyom, Chaisak, Pornputtapong, Natapol, Asasutjarit, Rathapon, Loftsson, Thorsteinn, Jansook, Phatsawee

“…Fenofibrate (FE) has been shown to markedly reduce the progression of diabetic retinopathy and age-related macular degeneration in clinical trials and animal…”
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Solubilization and in vitro permeation of dovitinib/cyclodextrin complexes and their aggregates by Jansook, Phatsawee, Praphanwittaya, Pitsiree, Sripetch, Suppakan, Loftsson, Thorsteinn

“…Dovitinib (DOV) is a tyrosine kinase inhibitor affecting the vascular endothelial growth factor and antiangiogenic activity. It has been studied in tumor and…”
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Voriconazole Eye Drops: Enhanced Solubility and Stability through Ternary Voriconazole/Sulfobutyl Ether β-Cyclodextrin/Polyvinyl Alcohol Complexes by Soe, Hay Man Saung Hnin, Kerdpol, Khanittha, Rungrotmongkol, Thanyada, Pruksakorn, Patamaporn, Autthateinchai, Rinrapas, Wet-Osot, Sirawit, Loftsson, Thorsteinn, Jansook, Phatsawee

“…Voriconazole (VCZ) is a broad-spectrum antifungal agent used to treat ocular fungal keratitis. However, VCZ has low aqueous solubility and chemical instability…”
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Physicochemical and Stability Evaluation of Topical Niosomal Encapsulating Fosinopril/γ-Cyclodextrin Complex for Ocular Delivery by Hnin, Hay Marn, Stefánsson, Einar, Loftsson, Thorsteinn, Asasutjarit, Rathapon, Charnvanich, Dusadee, Jansook, Phatsawee

“…This study aimed to develop a chemically stable niosomal eye drop containing fosinopril (FOS) for lowering intraocular pressure. The effects of cyclodextrin…”
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Aqueous solubility of kinase inhibitors: III the effect of acidic counter ion on the dovitinib/γ-cyclodextrin complexation by Praphanwittaya, Pitsiree, Jansook, Phatsawee, Loftsson, Thorsteinn

“…Dovitinib, a hydrophobic kinase inhibitor (KI), is lipophilic anticancer agent that forms water-soluble complexes with cyclodextrins (CDs). However,…”
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A Current Overview of Cyclodextrin-Based Nanocarriers for Enhanced Antifungal Delivery by Soe, Hay Man Saung Hnin, Maw, Phyo Darli, Loftsson, Thorsteinn, Jansook, Phatsawee

“…Fungal infections are an extremely serious health problem, particularly in patients with compromised immune systems. Most antifungal agents have low aqueous…”
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Angiotensin converting enzyme inhibitors/cyclodextrin inclusion complexes: solution and solid-state characterizations and their thermal stability by Hnin, Hay Marn, Stefánsson, Einar, Loftsson, Thorsteinn, Rungrotmongkol, Thanyada, Jansook, Phatsawee

“…Angiotensin converting enzyme (ACE) inhibitors have recently gained attention as a new class of drug in the therapeutic management of glaucoma. However, the…”
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Topical dexamethasone-cyclodextrin microparticle eye drops for diabetic macular edema by Tanito, Masaki, Hara, Katsunori, Takai, Yasuyuki, Matsuoka, Yotaro, Nishimura, Nobuhiro, Jansook, Phatsawee, Loftsson, Thorsteinn, Stefánsson, Einar, Ohira, Akihiro

“…To test the safety and efficacy of topical 1.5% dexamethasone aqueous eye drops with cyclodextrin microparticles for diabetic macular edema (DME). Nineteen…”
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Self-assembly of cyclodextrin complexes: Aggregation of hydrocortisone/cyclodextrin complexes by Messner, Martin, Kurkov, Sergey V., Brewster, Marcus E., Jansook, Phatsawee, Loftsson, Thorsteinn

“…A permeability profile of hydrocortisone from HPβCD solution saturated with the drug through semi permeable cellophane membrane with MWCO 15 kDa. Negative…”
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Development of amphotericin B nanosuspensions for fungal keratitis therapy: effect of self-assembled γ-cyclodextrin by Jansook, Phatsawee, Maw, Phyo Darli, Soe, Hay Man Saung Hnin, Chuangchunsong, Ravinsinee, Saiborisuth, Kitisak, Payonitikarn, Nawaporn, Autthateinchai, Rinrapas, Pruksakorn, Patamaporn

“…Propose Fungal keratitis is one of the major causes in loss of vision and blindness. Amphotericin B (AmB) is the first-line treatment of keratitis caused by…”
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Celecoxib/Cyclodextrin Eye Drop Microsuspensions: Evaluation of In Vitro Cytotoxicity and Anti-VEGF Efficacy for Retinal Diseases by Jansook, Phatsawee, Soe, Hay Man Saung Hnin, Asasutjarit, Rathapon, Tun, Theingi, Hnin, Hay Marn, Maw, Phyo Darli, Watchararot, Tanapong, Loftsson, Thorsteinn

“…Celecoxib (CCB), a cyclooxygenase-2 inhibitor, is capable of reducing oxidative stress and vascular endothelial growth factor (VEGF) expression in retinal…”
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Bio-Distribution and Pharmacokinetics of Topically Administered γ-Cyclodextrin Based Eye Drops in Rabbits by Kallab, Martin, Schuetzenberger, Kornelia, Hommer, Nikolaus, Schäfer, Bhavapriya Jasmin, Schmidl, Doreen, Bergmeister, Helga, Zeitlinger, Markus, Tan, Aimin, Jansook, Phatsawee, Loftsson, Thorsteinn, Stefansson, Einar, Garhöfer, Gerhard

“…The purpose of this study was to evaluate the ocular pharmacokinetics, bio-distribution and local tolerability of γ-cyclodextrin (γCD) based irbesartan 1.5%…”
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Carvedilol: Solubilization and Cyclodextrin Complexation: A Technical Note by Loftsson, Thorsteinn, Vogensen, Stine Byskov, Desbos, Cyrielle, Jansook, Phatsawee

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Self-assembled γ-cyclodextrin as nanocarriers for enhanced ocular drug bioavailability by Jansook, Phatsawee, Loftsson, Thorsteinn

“…[Display omitted] Cyclodextrins (CDs) are widely used in pharmaceutical products for improving the solubility and bioavailability of drugs through the…”
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Development and validation of high-performance liquid chromatography method for the simultaneous quantification of rivastigmine hydrogen tartrate and asiaticoside co-loaded in niosomes: A Box–Behnken design approach by Hnin, Hay Marn, Tun, Theingi, Jansook, Phatsawee

“…•The chromatographic parameters were optimized using a Box-Behnken experimental design.•The optimized HPLC–UV method was applied to simultaneously quantify…”
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