Search Results - "Jansen, Robert S"

Populist Mobilization: A New Theoretical Approach to Populism by Jansen, Robert S.

“…Sociology has long shied away from the problem of populism. This may be due to suspicion about the concept or uncertainly about how to fit populist cases into…”
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The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP by Szeri, Flora, Lundkvist, Stefan, Donnelly, Sylvia, Engelke, Udo F H, Rhee, Kyu, Williams, Charlene J, Sundberg, John P, Wevers, Ron A, Tomlinson, Ryan E, Jansen, Robert S, van de Wetering, Koen

“…The membrane protein ANKH was known to prevent pathological mineralization of joints and was thought to export pyrophosphate (PPi) from cells. This did not…”
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ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report by Jansen, Robert S, Duijst, Suzanne, Mahakena, Sunny, Sommer, Daniela, Szeri, Flóra, Váradi, András, Plomp, Astrid, Bergen, Arthur A, Oude Elferink, Ronald P.J, Borst, Piet, van de Wetering, Koen

“…OBJECTIVE—Mutations in ABCC6 underlie the ectopic mineralization disorder pseudoxanthoma elasticum (PXE) and some forms of generalized arterial calcification…”
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Resurrection and appropriation : Reputational trajectories, memory work, and the political use of historical figures by JANSEN, Robert S

“…The Zapatistas and Sandinistas both invoked historical figures in their rhetoric, but they did so in very different ways. This variation is explained by a…”
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MS2Query: reliable and scalable MS2 mass spectra-based analogue search by de Jonge, Niek F., Louwen, Joris J. R., Chekmeneva, Elena, Camuzeaux, Stephane, Vermeir, Femke J., Jansen, Robert S., Huber, Florian, van der Hooft, Justin J. J.

“…Metabolomics-driven discoveries of biological samples remain hampered by the grand challenge of metabolite annotation and identification. Only few metabolites…”
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Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis by Jansen, Robert S., Mandyoli, Lungelo, Hughes, Ryan, Wakabayashi, Shoko, Pinkham, Jessica T., Selbach, Bruna, Guinn, Kristine M., Rubin, Eric J., Sacchettini, James C., Rhee, Kyu Y.

“…Gene rv3722c of Mycobacterium tuberculosis is essential for in vitro growth, and encodes a putative pyridoxal phosphate-binding protein of unknown function…”
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ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release by Jansen, Robert S., Küçükosmanoğlu, Aslı, de Haas, Marcel, Sapthu, Sunny, Otero, Jon Andoni, Hegman, Ilse E. M., Bergen, Arthur A. B., Gorgels, Theo G. M. F., Borst, P., van de Wetering, Koen

“…Pseudoxanthoma elasticum (PXE) is an autosomal recessive disease characterized by progressive ectopic mineralization of the skin, eyes, and arteries, for which…”
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Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice by Krisko, Tibor I., Nicholls, Hayley T., Bare, Curtis J., Holman, Corey D., Putzel, Gregory G., Jansen, Robert S., Sun, Natalie, Rhee, Kyu Y., Banks, Alexander S., Cohen, David E.

“…Recent studies suggest that a key mechanism whereby the gut microbiome influences energy balance and glucose homeostasis is through the recruitment of brown…”
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Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection by Beites, Tiago, Jansen, Robert S., Wang, Ruojun, Jinich, Adrian, Rhee, Kyu Y., Schnappinger, Dirk, Ehrt, Sabine

“…The human pathogen Mycobacterium tuberculosis depends on host fatty acids as a carbon source. However, fatty acid β-oxidation is mediated by redundant enzymes,…”
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CinA mediates multidrug tolerance in Mycobacterium tuberculosis by Kreutzfeldt, Kaj M., Jansen, Robert S., Hartman, Travis E., Gouzy, Alexandre, Wang, Ruojun, Krieger, Inna V., Zimmerman, Matthew D., Gengenbacher, Martin, Sarathy, Jansy P., Xie, Min, Dartois, Véronique, Sacchettini, James C., Rhee, Kyu Y., Schnappinger, Dirk, Ehrt, Sabine

“…The ability of Mycobacterium tuberculosis ( Mtb ) to resist and tolerate antibiotics complicates the development of improved tuberculosis (TB) chemotherapies…”
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N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids by Jansen, Robert S., Addie, Ruben, Merkx, Remco, Fish, Alexander, Mahakena, Sunny, Bleijerveld, Onno B., Altelaar, Maarten, IJlst, Lodewijk, Wanders, Ronald J., Borst, P., van de Wetering, Koen

“…Despite technological advances in metabolomics, large parts of the human metabolome are still unexplored. In an untargeted metabolomics screen aiming to…”
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“Candidatus Hydrogenisulfobacillus filiaventi” strain R50 gen. nov. sp. nov., a highly efficient producer of extracellular organic compounds from H2 and CO2 by Hogendoorn, Carmen, Pol, Arjan, de Graaf, Rob, White, Paul B., Mesman, Rob, van Galen, Peter M., van Alen, Theo A., Cremers, Geert, Jansen, Robert S., Jetten, Mike S. M., Op den Camp, Huub J. M.

“…Production of organic molecules is largely depending on fossil fuels. A sustainable alternative would be the synthesis of these compounds from CO 2 and a cheap…”
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The potential role of drug transporters and amikacin modifying enzymes in M. avium by Schildkraut, Jodie A., Coolen, Jordy P.M., Ruesen, Carolien, van den Heuvel, Jeroen J.M.W., Aceña, Laura Edo, Wertheim, Heiman F.L., Jansen, Robert S., Koenderink, Jan B., te Brake, Lindsey H.M., van Ingen, Jakko

“…•MAC has probable drug efflux pumps.•EPIs are antibiotic specific.•M. avium can’t modify amikacin. Mycobacterium avium (M. avium) complex bacteria cause…”
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Coadministration of Ritonavir Strongly Enhances the Apparent Oral Bioavailability of Docetaxel in Patients with Solid Tumors by Oostendorp, Roos L, Huitema, Alwin, Rosing, Hilde, Jansen, Robert S, Ter Heine, Rob, Keessen, Marianne, Beijnen, Jos H, Schellens, Jan H M

“…Purpose: To enhance the systemic exposure to oral docetaxel by coadministration of ritonavir, an efficacious inhibitor of CYP 3A4 with minor P-glycoprotein…”
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What next for preimplantation genetic screening (PGS)? Experience with blastocyst biopsy and testing for aneuploidy by Jansen, Robert P.S., Bowman, Mark C., de Boer, Kylie A., Leigh, Don A., Lieberman, Devora B., McArthur, Steven J.

“…Blastocysts more commonly have a normal karyotype than cleavage-stage embryos do. Moreover, blastocysts have also made a metabolic transition from catabolism…”
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Multidrug Resistance Protein 2 Is an Important Determinant of Paclitaxel Pharmacokinetics by LAGAS, Jurjen S, VLAMING, Maria L, VAN TELLINGEN, Olaf, WAGENAAR, Els, JANSEN, Robert S, ROSING, Hilde, BEIJNEN, Jos H, SCHINKEL, Alfred H

“…Purpose: P-glycoprotein (P-gp; ABCB1 ) efficiently transports lipophilic amphipathic drugs, including the widely used anticancer drug paclitaxel (Taxol). We…”
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Activity-based annotation: the emergence of systems biochemistry by Rhee, Kyu Y., Jansen, Robert S., Grundner, Christoph

“…Current tools to annotate protein function have failed to keep pace with the speed of DNA sequencing and exponentially growing number of proteins of unknown…”
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Oral Administration of Gemcitabine in Patients with Refractory Tumors: A Clinical and Pharmacologic Study by Veltkamp, Stephan A, Jansen, Robert S, Callies, Sophie, Pluim, Dick, Visseren-Grul, Carla M, Rosing, Hilde, Kloeker-Rhoades, Susanne, Andre, Valerie A M, Beijnen, Jos H, Slapak, Christopher A, Schellens, Jan H M

“…Purpose: To determine the toxicity, tolerability, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of oral gemcitabine…”
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Situated political innovation: explaining the historical emergence of new modes of political practice by Jansen, Robert S.

“…Scholars have recognized that contentious political action typically draws on relatively stable scripts for the enactment of claims making. But if such…”
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An exercise-inducible metabolite that suppresses feeding and obesity by Li, Veronica L., He, Yang, Contrepois, Kévin, Liu, Hailan, Kim, Joon T., Wiggenhorn, Amanda L., Tanzo, Julia T., Tung, Alan Sheng-Hwa, Lyu, Xuchao, Zushin, Peter-James H., Jansen, Robert S., Michael, Basil, Loh, Kang Yong, Yang, Andrew C., Carl, Christian S., Voldstedlund, Christian T., Wei, Wei, Terrell, Stephanie M., Moeller, Benjamin C., Arthur, Rick M., Wallis, Gareth A., van de Wetering, Koen, Stahl, Andreas, Kiens, Bente, Richter, Erik A., Banik, Steven M., Snyder, Michael P., Xu, Yong, Long, Jonathan Z.

“…Exercise confers protection against obesity, type 2 diabetes and other cardiometabolic diseases 1 – 5 . However, the molecular and cellular mechanisms that…”
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